The sleep cycle is controlled by centers in the lower brain and follows a circadian rhythm of about a day. Sleep involves non-REM and REM stages in cycles lasting around 90 minutes each night. During sleep, vital signs like blood pressure and heart rate decrease while growth hormones increase. Inadequate sleep can cause irritability and difficulty concentrating. Sleep disorders can be primary, caused by issues like insomnia or sleep apnea, or secondary due to illnesses, stress, medications and other lifestyle factors. Polysomnography tests are used to diagnose sleep issues.