Pharmacovigilance AND ADVERSE DRUG REACTIONS.
MONITORING REPORTING ROLE OF PHARMACIST.
CLASSIFICATION OF ADR. MECHANISM OF ADR
ROLE OF PHARMACIST IN MANAGING ADR. AUGMENTED, BIZZARE, CONTINOUS, DELAYED, END OF TREATMENT, ABCD, ABCDE.
Pharmacovigilance AND ADVERSE DRUG REACTIONS.
MONITORING REPORTING ROLE OF PHARMACIST.
CLASSIFICATION OF ADR. MECHANISM OF ADR
ROLE OF PHARMACIST IN MANAGING ADR. AUGMENTED, BIZZARE, CONTINOUS, DELAYED, END OF TREATMENT, ABCD, ABCDE.
Drug Information Services, Drug information Sources, Illegal DIC, Drug Information Bulletin, Classification of scientific literature, services offered bu drug information services
Use of computers in hospital pharmacy, biostatistics and research methodology...shaistasumayya2
Computers in pharmacy are used for the information of drug data, records and files, drug management (creating, modifying, adding and deleting data in patient files to generate reports), business details.
Pharmacovigilance is science of detection,
assessment, reporting and prevention of adverse
reactions to drug(s).
Major aims of pharmacovigilance are:
1. Early detection of hitherto unknown adverse
reactions and interactions
2. Detection of increases in frequency of (known)
adverse reactions
3. Identification of risk factors and possible
mechanisms underlying adverse reactions
4. Estimation of quantitative aspects of benefit/risk
analysis and dissemination of information needed to
improve drug prescribing and regulation.
Definition, Types of drug distribution systems, Dispensing of drugs to ambulatory (outdoor) patients, Distribution of controlled drug, Novel drug distribution methods
REVIEWING THE CLINICIANS PRESCRIPTION AND TREATMENT PROGRESSION IS THE FUNDAMENTAL RESPONSIBILITY OF PHARMACIST. THIS PRESENTATION WILL DEAL WITH VARIOUS ASPECTS OF REVIEWING PATIENT DRUGTHERAPY PLAN
Drug Information Services, Drug information Sources, Illegal DIC, Drug Information Bulletin, Classification of scientific literature, services offered bu drug information services
Use of computers in hospital pharmacy, biostatistics and research methodology...shaistasumayya2
Computers in pharmacy are used for the information of drug data, records and files, drug management (creating, modifying, adding and deleting data in patient files to generate reports), business details.
Pharmacovigilance is science of detection,
assessment, reporting and prevention of adverse
reactions to drug(s).
Major aims of pharmacovigilance are:
1. Early detection of hitherto unknown adverse
reactions and interactions
2. Detection of increases in frequency of (known)
adverse reactions
3. Identification of risk factors and possible
mechanisms underlying adverse reactions
4. Estimation of quantitative aspects of benefit/risk
analysis and dissemination of information needed to
improve drug prescribing and regulation.
Definition, Types of drug distribution systems, Dispensing of drugs to ambulatory (outdoor) patients, Distribution of controlled drug, Novel drug distribution methods
REVIEWING THE CLINICIANS PRESCRIPTION AND TREATMENT PROGRESSION IS THE FUNDAMENTAL RESPONSIBILITY OF PHARMACIST. THIS PRESENTATION WILL DEAL WITH VARIOUS ASPECTS OF REVIEWING PATIENT DRUGTHERAPY PLAN
Assessment of Good Pharmacy Practice (GPP) in Pharmacies of Community Setting...iosrphr_editor
The IOSR Journal of Pharmacy (IOSRPHR) is an open access online & offline peer reviewed international journal, which publishes innovative research papers, reviews, mini-reviews, short communications and notes dealing with Pharmaceutical Sciences( Pharmaceutical Technology, Pharmaceutics, Biopharmaceutics, Pharmacokinetics, Pharmaceutical/Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmacognosy & Phytochemistry, Pharmacology, Pharmaceutical Analysis, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics and Biotechnology of Pharmaceutical Interest........more details on Aim & Scope).
Content is king. It's the stuff pharmacy rock stars are made of, the ingredients you'll use to cook up something so delicious that your customers eagerly anticipate your next course. The right dose of great content will reinforce your brand, and spectacular content will promote word of mouth from your customers to their friends and family.
Join us as we dive into some of these recipes that you can whip up in minutes, making your friends think you've been slaving over a hot stove all day. Let's get to the sizzle.
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The truth between the lines – Community pharmacists in improving the health o...inemet
PharmaCon2007 Congress, Dubrovnik, Croatia "New Technologies and Trends in Pharmacy, Pharmaceutical Industry and Education" http://www.pharmacon2007.com
Abstract is available at http://www.pharmaconnectme.com
Pharmacy design to customers specification and FPD Group Ltd guidance. Bespoke joinery in antique pear finish. Dispensary shelving catering for over 20, 000 prescriptions per month. Controlled drug cabinets and pharmacy fridges supplied
History Taking
1.Name, age, sex, marital status, occupation, address (Demographics)
2. Presenting complaints
3. History of present illness
4. Systemic inquiry
5. Past history
6. Menstrual history
7. Treatment history
8. Family history
9. Personal and social history
10. Occupational history
Patients and their loved ones often hold critical knowledge that informs diagnosis. This toolkit from the Institute of Medicine offers patients, families and clinicians guidance on how they can collaborate to improve diagnosis.
Presentation on medication history interview and soap notessuchitrauppicherla
pharmacy practice is vital activity performed by pharmadians along with physicians to enhance the quality and span of life of patient .mediaction history interview is is an essential to know and presentation of case collected in universally accepted format .
Introduction: Medication adherence is defined by the World Health Organisation as “The degree to which the person's behaviour corresponds with the agreed recommendations from a health care provider
Factor Affecting Non-Adherance:Poor adherence or non-adherence to medical treatment severely compromises patient outcomes and increases patient mortality.
Non-adherence is a very common phenomenon in all patients with drug-taking behaviour.
The complexity of adherence is the result of an interplay of a range of factors, including patient views and attributes, illness characteristics, social contexts, access, and service issues.
Non-adherence: Non-adherence is the failure or refusal to comply with advice and can imply disobedience on the part of patient
5 step Factors: Social/economic and Economic Factors
Provider-patient/health care system factors
Condition-related factors
Therapy-related factors
Patient-related factors
Behavioural Factors:
Life style (smoking, alcohol, coffee use) Psychological and personality factors: anxiety, depression, coping style
Biological factors:
Gender, age, and genetic predisposition
Social and cultural factors:
Educational level, living situation, price of medication, policies.
Information Factors:
Have you received enough information? Satisfaction with the last visit?
Awareness factors:
Severity of the complaints (Baseline) quality of life,
Locus of control about patient adherence:
internal and external, stability and control about the cause of the complaints: internal and external, stability and controllability.
Stages to Overcome This Barrier
this power point help new clinical pharmacist to start practice ,understand the concepts of clinical pharmacy and give them all the tools to give good care to the patient
pharmacist patient education and counseling Hemat Elgohary
Lack of sufficient knowledge about their health problems and medications cause of patients’ non-adherence to their pharmaco-therapeutic regimens and monitoring plans so pharmacist need to have skills and knowledge to improve patient adherence and reduce medication-related problems
Medication Adherence- Introduction
Definition
Causes of medication non-adherence
Pharmacist role in the medication adherence
Monitoring of patient medication adherence.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
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TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
1. Responding to symptoms
in
Community phaRmaCy
Dr. : Siham Gafer Altayib
B.pharm. Khartoum University
MSc. Community pharmacy
Queen’s University Belfast
2. CouRse objeCtives :
1- To outline structured approach to responding to
symptoms
2- To enable the student to identify common minor
illnesses that can be treated in the pharmacy.
3. 3.To enable the student to identify major diseases
that should be referred to the doctor.
4.To equip the student with the necessary skills and
knowledge to manage minor ailments presenting in
the pharmacy.
4. Impact of pharmacy on patient care
In the United Kingdom, the Pharmacy identified five main
areas in which pharmacy makes major contributions
to health outcomes:
5. 1 Management of prescribed medicines:
– dispensing of medicine
– counseling
2 Management of chronic conditions:
– repeat prescribing
– monitoring therapeutic outcomes
– improvement in quality of life
6. 3 Management of common ailments:
– counseling
– recommendation of line of action
4 Promotion and support of healthy
lifestyles:
– health education
– health screening
7. 5 Advice and support for other healthcare
professionals:
– provision of information on clinical and technical
aspects of use of medicines
– participation in research and development programs
to transfer science into practice
9. Community pharmacists are the health professionals
most accessible to the public.
They supply medicines in accordance with a
prescription or, when legally permitted,
dispense them without a prescription.
In addition to ensuring an accurate supply of
appropriate products,
10. their professional activities also cover:
1- counseling of patients at the time of dispensing of
prescription and non-prescription drugs
2- drug information to health professionals, patients
and the general public
3- and participation in health promotion
programs.
They maintain links with other health professionals in
primary health care.
12. Responding to symptoms is a major activity for the
community pharmacist.
Pharmacist receives every day loads and loads of requests
for advice about symptoms and the pharmacist supervises
a much greater number of over the counter (OTC) medicine
sales.
This role has always been important for the community
pharmacist.
13. • It was argued that in many cases pharmacists were not
asking enough or appropriate questions and therefore had
insufficient information to advice optimally the patient
about their symptoms.
.
14. • It was also criticized that the pharmacists do not
employ a safe and structured approach when
responding to patients’ symptoms and they fail to
differentiate between a symptom that might
suggest a more serious pathology or one which
can be easily managed with an OTC product.
15. For all these reasons, guidelines were issued
outlining a structured approach when dealing
with a patient requesting advice on symptoms.
It is essential for all pharmacists to be familiar
with these guidelines.
16. Approaches to differential diagnosis:
Acronyms :
This is a traditional way developed for
the community pharmacist to help them
remember what questions to ask to the
patient
17. In a busy pharmacy, interruptions may interfere with
dialogue between pharmacist and patient and the use of a
mnemonic to remind the pharmacists of the critical steps
involved in assessing the clinical significance of symptoms is
helpful.
• Use of a mnemonic will minimize the risk of missing
important information about the patient’s condition.
18. • There are three such methods which have been
suggested.
AS METHOD
WHAM
ENCORE
19. 1 WHAM :
The WHAM mnemonic was developed mainly for
use by counter assistants when responding to
symptoms.
It is shorter than the other techniques. The basis
of this mnemonic is:
20. W Who is the patient and what are the symptoms?
H How long have the symptoms been present?
A Action taken: what medicines have been tried?
M Medicines being taken for other problems?
21. Advantages :-
Establishes presenting compliant
Disadvantages :-
1- fails to consider general appearance of the
patient
2- no social life style factors taken into account
3- no family history
4- no history of previous symptoms
22. 2 ASMETHOD :-
The AS METHOD mnemonic identifies some of the main
questions which should be asked of each patient requesting
advice on symptoms. AS METTHOD translates as:
D Danger symptoms (which require referral to the doctor)?
23. A Age of the patient?
S Self or for someone else?
M Medicines the patient is taking?
E Extra medicines tried for the current symptoms?
T Time or duration of the symptoms?
T Taken anything for it or seen the doctor?
H History of any disease or condition?
O Other symptoms being experienced?
24. Advantages :-
establishes the nature of the problem & if the patient
has suffered from previous similar episodes
Disadvantages :
1- exact symptoms and severity not fully established
2- no social / life style factors taken into account
3- no family history
25. 3/ ENCORE :
ENCORE was developed as a structured approach to responding to
symptoms, in response to perceived shortcomings of community
pharmacists in this area of activity.
-Deficiencies highlighted by several surveys have included:
- Inadequate knowledge about specific therapies and products
- Suboptimal exploration with the patient of the symptoms
- Insufficient attention given to drug-drug interactions
- Omission of advice about referral to other experts when justified
- Generally insufficient communication with the patient.
26. 2ENCORE :
Letter meaning of the letter
E Explore
N No medication
C Care
O Observe
R Refer
E Explain
27. Advantages :
“ Observe “ section suggests taking into account the
appearance of the patient , does he or she looks poorly
Disadvantages :
1- section (no medication ) or ( refer ) add little to the
differential diagnosis process
2- no social / life style factors taken into account
3- no family history
28. The most popular Structured approach to responding to
symptoms is ENCORE :
Explore
Nature of symptoms
Obtain identity of patient
Concurrent medication or treatment
Exclude possibility of serious disease
Other associated symptoms
29. No medication
Remember that in many instances
medication is not necessary
Care
Geriatric patient
Pediatric patient
Lactating mothers
Pregnant women
30. Observe
Other tell tail signs
Demeanor of patient
Dramatization by patient
Refer Potentially serious cases
Persistent symptoms
Patient at increase risk
Explain
Discus with the patient why a
particular course of action is
suggested
31. E XPLORE
A)Nature of symptoms
The exact nature & site of the symptoms will often need clarification.
Dyspepsia and indigestion are used by patients to explain diverse non-
specific complaints.
Establishing the exact site of the gastric pain or discomfort would be
important.
1- Pain in the region of the abdomen just below the sternum usually
indicates that its origin is the upper elements of the GIT (oesophagus,
stomach and upper small intestine).
32. 2- A burning pain in this region radiating towards the throat
would be indicative of oesophagus.
3- “Sharp” may indicate a precisely-located pain, originating
from a gastric or peptic ulcer.
4- “Burning” may refer to gastric or oesophagitis.
5- Symptoms felt in the central region of the abdomen are
indicative of a condition further down the gut such as
gastro-enteritis and constipation
33. B) Obtain identity of patient
• It is always necessary to establish who the request is for. Assuming
the person asking for advice is the person suffering the symptoms is
not always correct.
For example, a wife may be requesting advice on a symptom which her
husband is experiencing, or vice versa. Although their ages are similar,
the symptoms of gastritis would be of greater concern in a male since
he will have a greater chance of suffering from coronary heart disease
than his wife. Conversely, gallstones conditions.
• Parents or grandparents will report the symptoms on behalf of a child.
It is important to be aware of this if a medicine is to be recommended,
since many preparations are contraindicated in children.
34. C) Concurrent Medication
• It is essential to establish if the patient is taking any medicines, whether
prescribed by a doctor or purchased OTC.
• There are four obvious reasons for this:
1- A medicine may be causing the symptoms
2- A medicine may indicate a disease state which could have a bearing on
management
3- The patient may already be taking a medicine the pharmacist is about to
recommend and which is not providing relief.
4- Medications that are recommended may interact with existing treatment.
35. D) Exclude possibility of a serious disease
Knowing if the patient has a history of disease may give important information.
Obese patients tend to suffer more frequently from gastritis than non-obese
people. This is often due to physical pressure on the stomach.
Large meals can cause symptoms due to the physical distension of the stomach.
Hiatus hernia is a condition in which the lower oesophagus or part of the stomach
slides through the diaphragm. This situation leads to more reflux of gastric acid.
36. E) Other Associated symptoms
• Other symptoms being experienced can help in the verification or
rejection of a ‘working diagnosis’.
• An ‘upset stomach’ may be a complex array of symptoms which
include: epigastric discomfort, pain, bloating, belching, feeling of
fullness, heartburn and nausea.
It may also be associated with vomiting but care must be taken in such
situations where vomiting is present since this may indicate a blockage
or, if the vomit is found to contain blood; it might indicate a bleeding
ulcer. Both of these conditions would require referral.
37. • The severity of pain must be established. Pain which
awakens the patient out of sleep is indicative of peptic ulcer
for example.
• Discomfort on swallowing food or drinks may be
experienced in gastritis. When a real difficulty in
swallowing (dysphagia) is experienced, the patient must
be referred to the doctor. This may indicate a physical
blockage due to carcinoma or due to the production of
scar tissue from repeated gastric reflux.
38. • Loss of weight in someone suffering from an ‘upset stomach’ must be
concerned as it may indicate carcinoma or bleeding ulcer.
Blood produced from bleeding ulcer can lead to the production of ‘tarry’ stool
which is difficult to pass.
• The aggravation of symptoms when bending down or on some sudden
physical exertion is usually indicative of dyspepsia.
Lying down allows acid to enter the oesophagus and aggravate the symptoms
which is why patients are sometimes recommended to raise the head of the bed.
•
39. The severity of pain must be established. Pain which awakens the patient
out of sleep is indicative of peptic ulcer for example.
• Discomfort on swallowing food or drinks may be experienced in gastritis.
When a real difficulty in swallowing (dysphagia) is experienced, the patient
must be referred to the doctor. This may indicate a physical blockage due to
carcinoma or due to the production of scar tissue from repeated gastric
reflux.
40. N O MEDICATION
If over indulgence of specific foods or alcohol can be identified as a possible
cause, then advice to avoid them may be all that is necessary.
C ARE
Special Care Group
Certain groups of patients, because of their vulnerability to the complications
of disease or their susceptibility to adverse drug reactions, will require special
consideration before a management strategy is decided. The four main groups
are:
41. The four main groups are:
1.The Geriatric Patient
They suffer from many more diseases than younger people and
therefore receive more medication than other groups of patients.
85 %of the elderly suffer from at least one chronic condition and the
average number of drugs taken by an elderly patient is 3.2.
42. • It is not unusual to see some elderly patient receiving 10 to 12 preparations
and consequently the risk of adverse drug reactions is very much greater
in the elderly.
• Pharmacist should always be aware that prescribing an OTC without
proper consideration of the patient’s current medication could worsen the
condition through drug interaction.
• The aging CNS makes elderly more susceptible to the effect of some
drugs and the physiological changes in various organs reduce the
excretion of drugs from the body
43. 2. The Paediatric Patients
Very young children, especially those in their first months of life are particularly
susceptible to the complications of what in older children would be regarded
as ‘minor condition’.
Neonates have a larger surface area to volume ratio compared to older
children and adults and are for example, at particular risk of dehydration from
diarrhoea.
.
44. Additionally, all children differ from adults in their response to
medicines.
Pharmacist will have difficulties in obtaining accurate information
about the symptoms since this will often be imparted by parents on the
children’s behalf, and often in their absence.
The assessment will be very subjective, reflecting the parents’ anxiety
or alternatively a lack of appreciation of the severity of the condition
45. 3. The Pregnant Patients
All drugs can potentially have an effect on the foetus during pregnancy.
In the first three months of gestation the risk of malformation being
highest from week three to week 11.
During the second and third trimesters, the effects of drugs tends to
be on growth and functional development of the foetus.
46. Drugs taken just before term or during labour can have an effect on the
neonate after delivery.
Many women do take medicines during pregnancy as the condition is often
associated with frequent symptoms.
The pharmacist should inform the patient that there is a lack of information on
the effect of most OTC medicines in pregnancy.
Certain medicines are known to cause definite adverse effects and therefore
should be avoided.
47. 4. Lactating Mothers
All mothers are being actively encouraged to breast-feed their babies.
Toxicity can occur in the infant if drugs are excreted in the breast milk.
Drugs which appear in milk in significant amounts to cause effect include
Aspirin, sedating antihistamines, caffeine, iodides, phenolphthalein and vitamin
A. Products containing these drugs, therefore, should be avoided in breast-
feeding mother.
48. O BSERVE
• A very important rule when dealing with patients presenting with
symptoms is to observe their general appearance. ‘Does the patient
look ill?’. This is the most valuable physical sign.
• A patient who is suffering from a bleeding peptic ulcer will look much
more ill than a patient who is suffering from simple dyspepsia.
49. • Non-verbal dramatisation, such as facial grimacing or the beating of a
clenched fist onto the area where discomfort or pain is being experienced, can
give useful information.
For example, a clenched fist beat onto an area indicates a sharp pain, whereas a
flattened hand rubbed around a general area would indicate discomfort.
50. R EFER
Potentially serious cases such as patients with peptic ulcer disease
(associated with pain) and gastric malignancy
(associated with anorexia) should be referred to a doctor. Tarry stools
may be seen in both conditions.
51. Recurrent and persistent symptoms require referral to the doctor.
Generally, if a symptom has lasted more than 10-14 days, the patient will
require referral.This recommendation will not apply in every case.
Someone suspected to be suffering from a heart condition should be
referred immediately. On the other hand, a patient who is under constant
supervision of a doctor will not need further referral unless there is a clear
condition deterioration.
Patients over the age of 40 are at increased risk of both peptic ulcer disease
and malignancy.
52. Example :
My daughter has diarrhea . Can you recommend something
I can give her ?
further information :
2 years old ,has diarrhea for one day – 4 bowel
movement in past 24 hours ( once a day is normal for
her ) . Stools are so loose but not liquid . No change in
diet at home but went to a party yesterday and don’t
Know what she ate there .
53. Explore :
( nature of symptoms , other associated symptoms , concurrent
medication and treatment , exclude possibility of serious disease )
-Determine how old is the patient
-How bad the diarrhea
-How long it has lasted
-What treatment had been tried
-The appearance of the stool
-If any one else in the family has been affected
54. No medication :
Except for rehydration , no medication is required
Antidiarrheal are contraindicated in infants
Exclude use of laxative
Care :
-As 2 years old dehydration is a real risk and a rehydration fluid
should be recommended particularly if elasticity of the skin
appears abnormally low
-Children under 3 years required referral if the condition
continues for more than 2 days
55. Observe and refer :
-A child who is very drowsy
-Diarrhea ( 3-4 motions ) with vomiting
-Diarrhea with fever may be serious
-Any sign of blood or bile
-persistent-,low grade diarrhea may accompany
amebic or giardial infection
56. Explain :
-Explain why oral rehydration (ORT) is the best treatment
-Why referral is advised
-In particular stress the need to seek medical help if the
condition persist
-ORT sachets should be made up with the correct volume of
water and once reconstituted , must be stored in the fridge and
drunk with in 24 hours