Rehabilitation

1. PhD, Associate Professor Yaroslava
Marunkevych
NATIONAL PIROGOV MEMORIAL MEDICAL UNIVERSITY, VINNYTSYA
DEPARTMENT OF PSYCHIATRY, NARCOLOGY AND PSYCHOTHERAPY WITH
THE COURSE OF POSTGRADUATE EDUCATION
GENERAL PRINCIPLES OF TREATMENT
AND REHABILITATION OF MENTAL
DISORDERS

2. General principles of treatment of
mental disorders.

3. Types of therapy in psychiatry:
1. Pharmacological treatment.
2. Psychotherapy.
3. Biological therapy (electroconvulsive
therapy).
4. Psychosurgery.
5. Social therapy and rehabilitation.

4. Types of pharmacological treatment:
Active
Stabilizing
Supportive
Struggle with side effects
(cyclodol)

5. Classification of psychoactive
medicines:
①Neuroleptics.
②Tranquillizers.
③Antidepressants.
④Mood stabilizers.
⑤Psychostimulants.
⑥Nootropics.

6. The classificatoin of neuroleptics according
to the pharmacological effect:
①Neuroleptics with primary sedative effect:
Chlorpromazine, Olanzapine.
②Neuroleptics with general antipsychotic effect:
Haloperidol, Risperidone, Clozapine.
③Neuroleptics with stimulating component:
Flupentixol.

7. Neuroleptics.
Classification:
①Typical (Haloperidol, Chlorpromazine,
Chlorprothixene).
②Atypical (clozapine, risperidone, quetiapine,
amisulpride, paliperidone, ziprasidone,
aripiprazole, sulpiride, sertindole, olanzapine).

8. Side effects of neuroleptics:
 Acute dystonia.
 Parkinsonism.
 Akathisia.
 Dyskinesia.
 Malignant neuroleptic
syndrome (therapy:
bromocriptine,
dantrolene).
 Endocrine
disorders:(hyperprolacti
nemia: gynecomastia,
galactorrhea, infertility;
obesity; impotence;
metabolic syndrome).
 Cardiovascular
disorders.
 Agranulocytosis.
Typical Atypical

9. Classificatoin of Tranquillizers:
①With sedative effect and drug dependence
(Diazepam, Phenazepam, Gidazepam).
②Without sedative effect and drug
dependence (Mebicar, Buspirone).

10. Classification of antidepressants:
1. MAO inhibitors: moclobemide.
2. Tricyclic antidepressants: amitriptyline, imipramine.
3. Tetracyclic antidepressants: Mianserin, Mirtazapine, Maprotilin.
4. Selective serotonin reuptake inhibitors: fluoxetine, paroxetine,
trazodone, citalopram, escitalopram.
5. Serotonin-Norepinephrine reuptake inhibitors: venlafaxine,
duloxetine.
6. Plant antidepressants: Hypericum.

11. Side effects of antidepressants:
① Anticholinergic effects (dry mouth, constipation,
disturbance of accommodation, dysuria).
② Cardiovascular (tachycardia, hypotension).
③ Gastrointestinal (nausea, vomiting).
① Hematological (leukocytosis, leukopenia, eosinophilia,
thrombocytopenia).
② Central (sedation or agitation, dizziness, drowsiness or
insomnia, etc.).
③ Allergic reactions.

12. Mood stabilizers
I. Lithium:
 Lithium carbonate.
 Lithium oxybutyrate.
II. Anticonvulsants:
 Carbamazepine.
 Sodium valproate.
 Lamotrigine.

13. Psychostimulants
1. Methylphenidate.
2. Sidnocarb.
3. Caffeine.
Dependence!

14. Nootropics
1. Neuromethabolic stimulants: piracetam,
GABA, glycine, cerebrolysin, actovegin.
2. Antioxidants: tocopherol.
3. Vasotropic drugs: vinpocetine, cinarisin,
ginkgo biloba.
4. Stimulators of memory and learning
processes:
a. Acetylcholinesterase inhibitors:
galantamine, donepezil, rivastigmine.
b. NMDA-receptor blockers: memantine.