This document summarizes research on bionic eye technologies, including the Argus II and Alpha IMS retinal prosthesis devices. It provides background on common eye diseases like retinitis pigmentosa and age-related macular degeneration. Clinical trials show that the Argus II and Alpha IMS devices helped some patients detect light, objects, and even read to varying degrees. However, challenges remain in providing long-term power and interfacing with the brain. Overall, bionic eyes demonstrate the potential to restore vision but further developments are needed to improve functionality.
in this presentation we have worked in the theme of bio MEMS in the midical staffs specially in bionic eye
this technologie help blind peopls to get there vision back
thanks to Pr.brandly in 1960 how invented the first device which colled bionic eye
IT IS THE NEW SIDE OF LIFE SCIENCE WHICH CAN IMPROVE THE FUNCTIONALITY OF DAMAGE PART OF THE EYE , IN THIS PPT VARIOUS TECHNIQUES ARE DESCRIBED ON BIONIC EYE.
Bionic eye is a device that can provide sight-detection of light.
Researches working for the Boston Retinal Implant Project have been developing Bionic eye implant that could restore the eye sight of people who suffer from age related blindness.
It is based on a small chip that is surgically implanted behind the retina, at the back of the eye ball.
Ultra thin wires strengthens the damaged optic nerve.
The user should wear special eye glasses battery powered camera and a transmitter.
in this presentation we have worked in the theme of bio MEMS in the midical staffs specially in bionic eye
this technologie help blind peopls to get there vision back
thanks to Pr.brandly in 1960 how invented the first device which colled bionic eye
IT IS THE NEW SIDE OF LIFE SCIENCE WHICH CAN IMPROVE THE FUNCTIONALITY OF DAMAGE PART OF THE EYE , IN THIS PPT VARIOUS TECHNIQUES ARE DESCRIBED ON BIONIC EYE.
Bionic eye is a device that can provide sight-detection of light.
Researches working for the Boston Retinal Implant Project have been developing Bionic eye implant that could restore the eye sight of people who suffer from age related blindness.
It is based on a small chip that is surgically implanted behind the retina, at the back of the eye ball.
Ultra thin wires strengthens the damaged optic nerve.
The user should wear special eye glasses battery powered camera and a transmitter.
There are millions of blind people who are hoping that medical technology would enable them to see the world one day. Well, the day is not far when the use of a bionic eye would be a routine medical procedure, which gives near perfect vision. Blind people would ultimately be able to recognize faces with the device. U.S and German scientists have designed a bionic eye to allow blind people to see again. The word “bionic” is derived from BIo+electrONIC.A bionic eye or visual prosthesis is a form of neural prosthesis intended to partially restore lost vision or amplify existing vision. It usually takes the form of an externally-worn camera that is attached to a stimulator on the retina, optic nerve, or in the visual cortex, in order to produce perceptions in the visual cortex. In simple words we say that itis an eye that works by itself, our brain controls it just like a real eye.Mr. Gregg Suaning created the design of bionic eye.A new artificial retina, an array of electrodes implanted on the back of the eye, has participants who had the implant for at least three months, 10 of the patients subsequently tested were able to identify the direction of moving objects.
There are millions of blind people who are hoping that medical technology would enable them to see the world one day. Well, the day is not far when the use of a bionic eye would be a routine medical procedure, which gives near perfect vision. Blind people would ultimately be able to recognize faces with the device. U.S and German scientists have designed a bionic eye to allow blind people to see again. The word “bionic” is derived from BIo+electrONIC.A bionic eye or visual prosthesis is a form of neural prosthesis intended to partially restore lost vision or amplify existing vision. It usually takes the form of an externally-worn camera that is attached to a stimulator on the retina, optic nerve, or in the visual cortex, in order to produce perceptions in the visual cortex. In simple words we say that itis an eye that works by itself, our brain controls it just like a real eye.Mr. Gregg Suaning created the design of bionic eye.A new artificial retina, an array of electrodes implanted on the back of the eye, has participants who had the implant for at least three months, 10 of the patients subsequently tested were able to identify the direction of moving objects.
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rapportfinale-170503124839.pptx
1. 1
Academic year 2016/2017
Republic of Tunisia
University of Sousse
Higher Institute of Applied Sciences and
Technology
BIO MEMS technology and application :
Bionic eye
Elaborated by : El –AGUECH Mohamed Amin
TALBI Malek
Supervised by: Dr. GUEDRI Lamia
3. Develop technology to be effective for
visual disabilities: BIONIC-EYE
Blindness:40million
Low
vision:128million
Normal vision
Common goal
[1]
3
4. Motivation :
What Is a Bionic Eye?
Huge revolution in the field of
medicine: Hope for the blind
Replaces functionality for a part or the
whole eye
Chips specifically designed to imitate
retina characteristics
4
The first prototype : Brindley in 1960s who improvised a device on the cerebral cortex
6. Progressive degeneration of the rod photoreceptor cells in
the retina.
Retinitis pigmentosa (RP):
Hereditary Genetic Disease
Peripheral Rods degenerate
Gradually progresses towards
center of eye
Tunnel vision results
6
8. Age related macular degeneration(AMD):
Genetically Related
Cones in the macula region degenerate
Loss of central vision
Peripheral Retina spared
Common among old people
8
11. Experimental visual device restore functional vision
rectifies RP and AMD to an extent
Two of retinal prosthesis :
Epiretinal implantaion :ARGUS II
device
Subritinal implantaion : Alpha
IMS device
11
12. 12
ARGUS II : [2]
The first approved device in clinical trials : USA and Europe.
Components : 3 external components and 3 internal components.
Micro -Camera
Visual Processing Unit: VPU
Wireless
transmitter
Electronics case
Wriless antenna
Multi-electrode array (60electrodes)
With this system working with a camera, the patient has to turn
the whole head and not just the eyes to look around.
13. 13
Who is eligible ?
Age 25 or older
Bare light or no light perception in
both eyes
Being able to receive the
recommended post-implant
clinical follow-up, device fitting,
and visual rehabilitation .
14. 14
Alpha IMS device : [3]
Foil substrate Power supply cable
Alpha-IMS has been involved in clinical trials in Europe and Hong Kong.
It does not depend on an external camera but a totally implantable
structure
Return electrode
Ceramic housing
CMOS chip
(1500 electrodes )
15. Eligibility ? Same Criteria as the Argus II device.
Number of micro electrodes:1500
16 electrodes
15
+200electrodes +1000 electrodes
17. •9 females
•21 males
Number of
patients
•58
•+- 10
Main age
• 35,2
• +-11,5
Years since
diagnosis the
problems
Argus II statistics :
17
18. Tests :
Orientation and Mobility:
Finding the door
50
40
30
20
10
0
60
after 3
manths
after 6
manths
faile Colonne1
Room with walls of uniform color Faisluuccress
Success
18
19. After 5 years:
19
60% of patients (18/30) had experienced no device- or
surgery-related SAEs*
Only 1 patient had a SAE after the 3rd year of
implantation
1 case of retinal detachment was noticed after 4,5 years
One patient died at 6 years after implantation of natural
causes unrelated to the Argus II.
*SAE : Serious Adverse Event
20. • 13 females
• 16 males
Number of
patients
• 58
• +- 8,2
Main age
• 35,2
• +-11,5
Years since
diagnosis the
problems
Alpha IMS statistic :
20
21. Test :
Ability to see objects and shapes
Reading letters and words
ability to read newspaper
headlines.
patients could see light, doors,
and windows
could detect whether a light was
on or off
patients did not respond to
implantation
21
Test’s results :
23. Limits
Advantages
The technology may enable
people to recognize faces
and facial expressions.
Water-proof and corrosion- proof
: The chip is enclosed in a titanium casing
Expected Durability : 10 years
The unfortunate people who were
born blind do not have the
neurological capability to process
the data received via the wire.
The optic nerve must be at
least partly functional or else
the data will not be fully
processed.
23
25. The results provide proof of principle that a subretinal (IMS)
and epritinal (Argus) implant can restore reliably measurable
visual function.
25
to do more than
Now Bionic devices are developing
replacing defective parts.
26. Providing
26
power to run bionic implants and
making connections to the brain's control system
pose the two great challenges for biomedical
engineering.
We are now looking at devices like bionic arms,
tongues, noses etc.
28. 1 Brig A Banarji , Col VS Gurunadh, Col S Patyal , Col TS Ahluwalia, Maj Gen DP
Vats, SM, VSM, Col M Bhadauria : Visual Prosthesis : Artificial Vision
2Tai-Chi Lin, Hua-Ming Chang , Chih-Chien Hsu , Kuo-Hsuan Hung , Yan-Ting
Chen , Szu-Yu Chen , Shih-Jen Chen : Retinal prostheses in degenerative retinal
diseases , Journal of the Chinese Medical Association (2015)
3Katarina Stingl , Karl Ulrich Bartz-Schmidt , Dorothea Besch , Caroline K.
Chee , Charles L. Cottriall , Florian Gekeler a , Markus Groppe , Timothy L.
Jackson , Robert E. MacLaren , Assen Koitschev , Akos Kusnyerik , James
Neffendorf , Janos Nemeth , Mohamed Adheem Naser Naeem , Tobias
Peters h , James D. Ramsden l , Helmut Sachs , Andrew Simpson , Mandeep
S. Singh , Barbara Wilhelm , David Wong , Eberhart Zrenner(2015) .
Subretinal Visual Implant Alpha IMS. Vision Research
28