This document discusses radiology modalities used to assess the renal system. It covers ultrasound, x-ray, CT, MRI, and nuclear scans. Ultrasound and MRI do not use ionizing radiation, while nuclear scans are unique in assessing renal function. Common renal pathologies include cysts, stones, hydronephrosis, pyelonephritis, tumors, and congenital diseases. The document also reviews ureter and bladder conditions such as vesicoureteral reflux, cystitis, and benign prostate hypertrophy.
uses and indication of radiology in surgeryanimesh kunwar
1.Introduction
2.Diagnostic modalities in radiology
3.Role of radiological imaging in emergency surgical situation
4.Role of radiological imaging in elective surgical situation
5.Conclusion
A presentation about Intravenous Urography (Also known as Intravenous Pyeography).
The presentation contains 41 slides, and is divided into 4 parts :
1 - Introduction.
2 - The procedure.
3 - Examples for abnormal findings.
4 - Studies comparing IVU accuracy with KUB & USG with CT Scan.
This presentation was prepared and presented by me in the tutorials of the Radiology Department of Sebha Medical Center.
uses and indication of radiology in surgeryanimesh kunwar
1.Introduction
2.Diagnostic modalities in radiology
3.Role of radiological imaging in emergency surgical situation
4.Role of radiological imaging in elective surgical situation
5.Conclusion
A presentation about Intravenous Urography (Also known as Intravenous Pyeography).
The presentation contains 41 slides, and is divided into 4 parts :
1 - Introduction.
2 - The procedure.
3 - Examples for abnormal findings.
4 - Studies comparing IVU accuracy with KUB & USG with CT Scan.
This presentation was prepared and presented by me in the tutorials of the Radiology Department of Sebha Medical Center.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
This presentation explores a brief idea about the structural and functional attributes of nucleotides, the structure and function of genetic materials along with the impact of UV rays and pH upon them.
2. Radiology
Team 437
Objectives:
• Modality used for assessment of the urinary system
▫ X-ray
▫ US
▫ CT
▫ MRI
▫ Nuclear
• Normal anatomy
• Common pathologies
▫ Kidney
▫ Ureter
▫ Bladder
▫ Urethra
4. Radiology
Team 437
Ultrasound
Image Key:
White = stones and calcification.
Grey = soft tissue.
Black = fluid.
Pros (Advantages)
Portable
Inexpensive
No ionizing radiation
Cons (Disadvantages)
Time consuming
Operator dependent(depends
on the skill of the operator).
-Ultrasound: Sound waves that reflect off dense surfaces, giving us a
hyper–echoic view of the surface.
-Objects with less density appear in gray such as sub tissue
-Fluids such as water and urine will not reflect the sound wave
-The renal pelvis appears white because it is filled with fat
5. Radiology
Team 437
X-RAY
Pros (Advantages)
Inexpensive
Quick
Cons (Disadvantages)
Ionizing radiation
Not definitive
IVP
-Intravenous pyelogram commonly used on
the renal system
-patient is given contrast which appears bright
after entering the renal system
-you can tell if there is any stone or
obstruction in the ureter
-contrast is given Intravenously, and it ends up
being excreted by the kidneys
Not commonly used on the renal system.
IVP
Image Key:
White = bone and calcification.
Grey = soft tissue.
Black = air.
6. Radiology
Team 437
CT MRI
Stands for (Magnetic Resonance Imaging)
Multi leveled X ray, which gives a more definitive and
clearer images.
Pros (Advantages)
Quick
A lot of information(can view
.
(
small structures in the kidney
Cons (Disadvantages)
Ionizing radiation
Expensive
Image key: same as X ray
White = bones and calcification.
Grey = soft tissue.
Black = air.
Pros (Advantages)
No ionizing radiation(uses
magnetic fields).
A lot of information(can be
used in pregnancy).
Cons (Disadvantages)
Time consuming
Expensive
Image key:
White = high intensity.
Grey to black = low intensity.
7. Radiology
Team 437
Nuclear scans
-The patient is given radioactive materials which give
off gamma rays, these rays can be detected by special
cameras.
-This picture shows that the right kidney filtered the
radioactive material while the left one did not.
Pros (Advantages)
assess the function
Cons (Disadvantages)
Time consuming
radioactive materials
8. Radiology
Team 437
Summary
-Ultrasound and MRI are the only ones with no ionizing radiation
-Nuclear scan is the only one that can asses the function(not only the anatomic structure)
12. Radiology
Team 437
Urinary bladder
-Black in Ultrasound(because it’s fluid)
-We use it to asses the amount of urine in
bladder
-Smooth muscle of the bladder
-Tumors will cause irregularities
14. Radiology
Team 437
Cysts
It is benign, common and predominantly incidental.
-Here it’s cyst not tumor, why?
Because it has well demarcated fluid inside
Anechoic circular mass , clear borders.
Hypo-dense clear border
mass in right kidney.
Cysts: are sac-like structures that may be filled
with gas, liquid, or solid materials.
15. Radiology
Team 437
Stones
• Radio-opaque (calcium , struvite)
(can be seen in X-RAY)
• Radio-lucent (uric acid , cysteine)
(can’t be seen in X-RAY)
The best modality for the diagnosis
of renal stones is non-contrast CT
Struvite: (magnesium ammonium phosphate)
-Contrast CT will mask the stones because
the whole area will become bright
-In the other hand non-contrast CT will only
make the stones appear bright as you can
see in the picture.
16. Radiology
Team 437
Pelvic brim junction: intersection of
iliac arteries and ureter
Uretropelvic junction.
Stones
-Here we have a stone in the
Uretropelvic junction -Here we have a stone in the Pelvic
brim junction
17. Radiology
Team 437
Hydronephrosis
-A block in the drainage of the renal system which causes
the urine to accumulate in the renal pelvis.
-When there is a complete obstruction to the ureter by a
stone , the kidney eventually fills with urine and become
swollen along the ureter
Pyelonephritis
• It is the infection of the kidney.
• Acute pyelonephritis results from
bacterial invasion of the renal
parenchyma. Bacteria usually reach
the kidney by ascending from the
lower urinary tract.
• CT scan for a patient with
pyelonephritis, we do it only if the
patient doesn't respond to the
treatment or he had a recurrent
pyelonephritis.
-You can notice how the
kidney pelvis is dilated or
extended if you compare
it to the normal
ultrasound
18. Radiology
Team 437
End-stage renal
disease (ESRD)
-ESRD causes Kidney atrophy
-In the picture below we can see
atrophy in the left kidney
-The right kidney is trying to
compensate, that’s why it’s
hypertrophied
Tumors
1-Benign
most common type is
angiomyolipoma.
2-Malignant
most common type is
renal cell carcinoma.
21. Radiology
Team 437
vesicoureteral reflux disease
-This disease characterized by backflow of the urine
-How do we diagnose it ?
By giving the patient contrast , after that we will see it go
from the ureter back to kidney
Ureter pathology
22. Radiology
Team 437
Cystitis
Image 1: an inflamed urinary bladder
(thick surrounding walls).
Image 2: This bladder has gas bubbles that
could be due to inflammation or infection
from ‘gas producing’ bacteria.
Benign Prostate
Hypertrophy
Bladder
Prostate
-Hypertrophied prostate causing the
bladder to be compressed
Urinary bladder
pathologies
23. Radiology
Team 437
Quiz
1)What modality is cheap and with no Ionized radiation?
A- Ultrasound
B- X-ray
C- CT-scan
D- MRI
2)What modality is used to assess the function?
A- Nuclear scan
B- X-ray
C- MRI
D- CT scan
3)What modality is used with a lot of information and no Ionized radiation?
A- X-ray
B- Ultrasound
C- MRI
D- CT scan
4)What type of stones we can see under X-ray?
A- Radio-opaque
B- Radio-lucent
5)What is the best modality used to diagnose renal stones?
A- Contrast CT
B- Non-Contrast CT
6)What is the most common type of benign and malignant kidney tumors?
A- Transitional cell carcinoma/Renal cell carcinoma
B- Angiomyolipoma/Renal cell carcinoma
1-A 2-A 3-C 4-A 5-B 6-B
24. Radiology
Team 437
THANK YOU
Contact us
on:
@Radiology437
Radiology437@gmail.com
Team
Leaders:
Team
members:
Faisal
Alqusaiyer
Rawan
Alharbi
Abdullah
alsergani
Abdullah
Alomar
Mohannad
alamri
Afnan almustafa
For checking our
work.
Revised
by:
Homoud al
zaid
Adel
Mohammad alasqah
Abdulrahaman Altalasi
Abdullah Almeaither