The radial nerve provides motor innervation to the posterior arm and forearm muscles and sensory innervation to the back of the hand. It is susceptible to injury at various points along its course from the axilla to the forearm. High radial nerve palsies occur near the radial groove of the humerus and cause loss of wrist and finger extension while sparing elbow extension. Low radial nerve palsies affect function below the elbow. Physical exam assesses affected muscle groups and sensory areas. Treatment involves splinting and may include injections or surgery to repair the nerve or transfer tendons.