2. Congratulations on
your cycle start!
Everyone at RMA
wishes you success.
Introduction to In-Vitro Fertilization (IVF) Cycle
In
Vitro
Fertilization
Introduction
Stimulation
&
Trigger
Oocyte
Retrieval
Embryology
&
Transfer
3. In Vivo
In Vitro
Introduction to In-Vitro Fertilization (IVF) Cycle
In
Vitro
Fertilization
Introduction
Stimulation
&
Trigger
Oocyte
Retrieval
Embryology
&
Transfer
4. • In Vitro Fertilization, or IVF
involves bringing sperm and egg
together in a laboratory dish.
• Embryos are made and the best
embryos are used to help couples
conceive.
Introduction to In-Vitro Fertilization (IVF) Cycle
In
Vitro
Fertilization
Introduction
5. • Reasons for IVF:
– Tubal factor
– Severe Male Factor
– Endometriosis
– Ovulatory dysfunction
– Ovarian failure
– Diminished ovarian reserve
– Fertility preservation
– Unexplained infertility
Introduction to In-Vitro Fertilization (IVF) Cycle
6. Introduction to In-Vitro Fertilization (IVF) Cycle
Please confirm the following is complete prior
to starting your IVF cycle:
Checklist Blood Work
Consents are signed
Cleared by Finance
Cycle medications from specialty pharmacy
7. Introduction to In-Vitro Fertilization (IVF) Cycle
Oocyte
Retrieval
Embryology
&
Transfer
Stimulation
&
Trigger
Introduction
There are many IVF protocols which
are tailored to each patient specific
diagnosis, age, diagnosis and prior
responses to stimulation medications.
Your physician may prescribe estrogen
pills or birth control pills for pre-
treatment prior. These medications
help to synchronize your follicles prior
to starting your stimulation injections.
8. Introduction to In-Vitro Fertilization (IVF) Cycle
Injection Training
• Take the time to watch RMA’s injection
training videos
• Hormonal injections are administered
for 8 to 12 days in order to grow the
ovarian follicles and allow the eggs to
mature
• Expect to administer approximately 2-4
injections daily
www.rmanj.com/injection-training-videos
*Ask your nurse what injections your physician will be prescribing.
9. Introduction to In-Vitro Fertilization (IVF) Cycle
• Frequent ultrasounds and blood
work will be needed every 1 to 3
days through this time to monitor
progress.
• Your Nurse will call you with results
and medication instructions by 7pm.
• Please only page if you have not
received a call by 7pm
10. Introduction to In-Vitro Fertilization (IVF) Cycle –Morning Monitoring
Location
Weekday
Monitoring Hours
Weekend/Holiday
Monitoring Hours
Basking Ridge Mon-Fri 6:00am – 7:30am
Sat/Sun 6:00am – 10:00am
open every day
Eatontown Mon-Fri 6:00am – 7:30am
Sat/Sun 6:00am – 8:00am
open on holidays
Marlton Mon-Fri 6:00am – 7:30am
Sat/Sun 6:00am – 8:00am
open on holidays except Christmas Day
Morristown
West Orange
Somerset
Springfield
Englewood
Princeton
Freehold
Mon-Fri 6:00am – 7:30am Closed
Lehigh Valley, PA Daily 7:00am-8:30am Daily 7:00am-8:30am
Please make sure you arrive within designated monitoring hours in order to obtain same-day
results.
You can monitor at the office of your choice, but please let your Nurse know which office you plan
to visit
There is a Nurse available beginning at 7am to meet with patients that have questions or need to
review trigger instructions. Please be aware that many patients need to get to work, so time is
limited in the morning. If you have more complex questions, please ask your Nurse about
scheduling a meeting time.
11. Introduction to In-Vitro Fertilization (IVF) Cycle
Ultrasounds Blood work
Injections
Pre-
Treatment
Stimulation
8-12 Days
Trigger
12. Introduction to In-Vitro Fertilization (IVF) Cycle
• Trigger Injection
– Novarel/Pregnyl/Ovidrel/Lupron
Trigger
– Stimulate ovulation (releasing of
eggs)
– ***Time specific injection
– Retrieval 36 hrs. later (i.e. 7pm
trigger time on Monday results in 7am
egg retrieval on Wednesday)
• Egg Retrievals take place in our
Basking Ridge office
13. Day of Egg Retrieval:
• Nothing to eat or drink after
midnight the day prior to retrieval
• Partners are not allowed in the
Operating Room
• No children allowed
• You will not be able to drive day of
retrieval. A responsible adult must
accompany you home.
Introduction to In-Vitro Fertilization (IVF) Cycle
Embryology
&
Transfer
Oocyte
Retrieval
Stimulation
&
Trigger
Introduction
14. Male Partner (if applicable)
• 2-5 days of abstinence if
producing a fresh semen
specimen on the day of
oocyte retrieval
Introduction to In-Vitro Fertilization (IVF) Cycle
15. Introduction to In-Vitro Fertilization (IVF) Cycle
Egg retrievals are performed approximately 36
hours after the scheduled trigger injection.
16. What to Expect on the Day of Your Egg Retrieval
• IV Sedation
• Egg retrievals are an ultrasound guided
procedure, which takes approximately 10-20
minutes
• Learn how many eggs are retrieved that day
17. Introduction to In-Vitro Fertilization (IVF) Cycle
Night of the Procedure
Call the office if you experience:
• Temperature above 101
• Persistent nausea or vomiting
• Severe abdominal pain or swelling
• Heavy vaginal bleeding
• Shortness of breath
• Fainting
• Pain, burning, redness and or swelling in
area around IV site
Vaginal spotting and/or mild abdominal cramping may occur and is normal.
18. The Next Day = Day 1
Fertilization Check
Introduction to In-Vitro Fertilization (IVF) Cycle
Embryology
Oocyte
Retrieval
Stimulation
&
Trigger
Introduction
20. Introduction to In-Vitro Fertilization (IVF) Cycle
• The day after your egg retrieval, a
nurse will call you with fertilization
results or number of eggs we were
able to freeze.
• The next embryology update will be
7 days following your egg retrieval
with how many embryos were
available to freeze.
21. Introduction to In-Vitro Fertilization (IVF) Cycle
Post Egg Retrieval
• Please call your nurse with day 1 of
your period following your egg
retrieval
• If your treatment plan involves
screening your embryos for
chromosomal abnormalities please
expect results in approximately 2
weeks from the day of embryo
biopsy.
22. Introduction to In-Vitro Fertilization (IVF) Cycle
Please contact your
nurse with any
questions or
concerns.
Editor's Notes
This is a gentle reminder that several things need to be done before the start of your IVF cycle. You will need to ensure your checklist is complete, consents are signed by both you and your partner if applicable, and that you are cleared by finance to begin your cycle. We also ask that you make sure you have all of your cycle medications in your possession as RMA does not keep any medications in our offices. Frequently, these medications require prior authorization by your insurance company and need to be purchased through a specialty pharmacy. We ask that you please plan accordingly.