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Our joints are subject to wear and tear and with increasing age the lining of joints, the cushioning cartilage, gradually degenerates. When cartilage has reached significant abrasion articular tissue will be affected and tissue trauma initiates a local inflammation. The consequence is a reduced flexibility of joints and predominantly pain. Inflammatory cells accelerate degeneration of joints by secreting reactive oxygen species (“oxidative
burst”), pro-inflammatory cytokines and degenerative enzymes matrix metalloproteinases (MMPs).
This process is paralleled by increasing pain which, left untreated, may reach excruciating levels.
Corticosteroids in dentistry and endodonticsDr. Ritu Gupta
this seminar provides information about the corticosteroids ,history,uses, functional anatomy of adrenal glands, it's drawbacks, cushing's habitus, dental implications, mineralocorticoids, glucocorticoids
Our joints are subject to wear and tear and with increasing age the lining of joints, the cushioning cartilage, gradually degenerates. When cartilage has reached significant abrasion articular tissue will be affected and tissue trauma initiates a local inflammation. The consequence is a reduced flexibility of joints and predominantly pain. Inflammatory cells accelerate degeneration of joints by secreting reactive oxygen species (“oxidative
burst”), pro-inflammatory cytokines and degenerative enzymes matrix metalloproteinases (MMPs).
This process is paralleled by increasing pain which, left untreated, may reach excruciating levels.
Corticosteroids in dentistry and endodonticsDr. Ritu Gupta
this seminar provides information about the corticosteroids ,history,uses, functional anatomy of adrenal glands, it's drawbacks, cushing's habitus, dental implications, mineralocorticoids, glucocorticoids
A presentation by Kim Ekelund at the 2017 meeting of the Scandinavian Society of Anaestesiology and Intensive Care Medicine.
All available content from SSAI2017: https://scanfoam.org/ssai2017/
Delivered in collaboration between scanFOAM, SSAI & SFAI.
The CDC recently released guidelines regarding the use of opioid medications in the treatment of chronic pain. The CDC recommends that clinicians should consider nonpharmacologic therapies like medical foods as a first line therapy to safely and effectively treat chronic pain.
Study of moringa_effect_on_gastric_and_duodenal_ulcersSilentdisco Berlin
Moringa is a plantfood of high nutritional value, ecologically and economically beneficial and readily available in the countries hardest hit by the food crisis. http://miracletrees.org/ http://moringatrees.org/
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THERAMINE is a safe and effective option for the dietary management of pain without the adverse side effects associates with opioids, NSAIDs or acetaminophen. The efficacy and safety of THERAMINE is supported by two double blind clinical trials and over a decade of clinical use. To learn more about THERAMINE please call (844) 474-3111 or visit www.medicalfoods.com.
anti oxidant & anti inflammatory from pine bark to help improving on cardiovascular health, diabetes, erectile dysfunction, melasma, muscle cramp, osteoarthritis, retinopathy
A presentation by Kim Ekelund at the 2017 meeting of the Scandinavian Society of Anaestesiology and Intensive Care Medicine.
All available content from SSAI2017: https://scanfoam.org/ssai2017/
Delivered in collaboration between scanFOAM, SSAI & SFAI.
The CDC recently released guidelines regarding the use of opioid medications in the treatment of chronic pain. The CDC recommends that clinicians should consider nonpharmacologic therapies like medical foods as a first line therapy to safely and effectively treat chronic pain.
Study of moringa_effect_on_gastric_and_duodenal_ulcersSilentdisco Berlin
Moringa is a plantfood of high nutritional value, ecologically and economically beneficial and readily available in the countries hardest hit by the food crisis. http://miracletrees.org/ http://moringatrees.org/
AppTrim® is a medical food manufactured in a cGMP certified facility in the United States, that is specially formulated to manage the increased nutritional requirements of obesity. AppTrim provides the specific amino acids and nutrients required by the body to stimulate the production of key neurotransmitters responsible for controlling appetite, hunger and satiety. AppTrim is clinically proven to reduce appetite, carbohydrate cravings and weight when used in addition to a daily exercise and nutrition plan
THERAMINE is a safe and effective option for the dietary management of pain without the adverse side effects associates with opioids, NSAIDs or acetaminophen. The efficacy and safety of THERAMINE is supported by two double blind clinical trials and over a decade of clinical use. To learn more about THERAMINE please call (844) 474-3111 or visit www.medicalfoods.com.
anti oxidant & anti inflammatory from pine bark to help improving on cardiovascular health, diabetes, erectile dysfunction, melasma, muscle cramp, osteoarthritis, retinopathy
Efficacy of Anti-Melanogenic and Anti-Ageing Properties of Glutathione with A...IJSRP Journal
Widespread concerns regarding the rise in prevalence of skin cancer and the adverse effects of both acute and chronic photo-damage due to exposure to UV rays, has led to various modes of treatment. The latest development in this regard is the findings about Glutathione and Polypodium dry extract as potential treatment components for skin conditions. Glutathione plays pivotal role in protecting cells against oxidative stressinduced cellular damage and in detoxifying Xenobiotics and drug metabolism. The added photo-protective effects of oral Polypodium with its antioxidant, immunoregulatory and antiinflammatory properties aid also in prevention of chronic skin damage, photoaging, and skin cancer led by UV exposure. Its decreased levels are associated with the common features of aging as well as of a wide range of pathological conditions, including neurodegenerative disorders.
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Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Integrating Ayurveda into Parkinson’s Management: A Holistic ApproachAyurveda ForAll
Explore the benefits of combining Ayurveda with conventional Parkinson's treatments. Learn how a holistic approach can manage symptoms, enhance well-being, and balance body energies. Discover the steps to safely integrate Ayurvedic practices into your Parkinson’s care plan, including expert guidance on diet, herbal remedies, and lifestyle modifications.
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
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Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.