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Publication List

A.   Papers
1. The acid mediated intramolecular 1,3- dipolar cycloaddition of 2- Nitro- 1,1
     ethenediamine derived nitrile oxides for the synthesis of novel fused bicyclic
     isoxazoles; Page, Lee W.;
      Bailey, Matthew.; Beswick, Paul J.; Frydrych Simon.; Gleave, Robert J. for prospective
      publication in Tetrahedron Letters (with the Editors)
2.   The intramolecular amination of allenes; Feast, George C.; Page, Lee W.;
     Robertson, Jeremy.; "in press" and can be cited as Chem. Commun., 2010, 46, DOI:10.1039/
     b926179f
3.   Synthesis and evaluation of 3- amino- 6- aryl- pyridazines as selective CB2
     agonists for the treatment of inflammatory pain; Gleave, Robert J.; Beswick, Paul J.;
     Brown, Andrew J.; Giblin, Gerard M. P.; Goldsmith, Paul; Haslam, Carl P.; Mitchell, William L.;
     Nicholson, Neville H.; Page, Lee W.; Patel, Sadhana; Roomans, Susan; Slingsby, Brian P.;
     Swarbrick, Martin E.; Bioorganic & Medicinal Chemistry Letters (2010), 20(2), 465-468.
     CODEN: BMCLE8 ISSN:0960-894X. AN 2009:1591711 CAPLUS
4.   An unusual methylene aziridine refined in P21/c and the nonstandard setting
     P21/n; Feast, George C.; Haestier, James; Page, Lee W.; Robertson, Jeremy; Thompson,
     Amber L.; Watkin, David J.; Acta Crystallographica, Section C: Crystal Structure
     Communications (2009), C65(12), o635-o638. CODEN: ACSCEE ISSN:0108-2701. AN
     2009:1534462 CAPLUS
5.   2- Amino- 5- aryl- pyridines as selective CB2 agonists: Synthesis and
     investigation of structure- activity relationships. Gleave, Robert J.; Beswick, Paul J.;
     Brown, Andrew J.; Giblin, Gerard M. P.; Haslam, Carl P.; Livermore, David; Moses, Andrew;
     Nicholson, Neville H.; Page, Lee W.; Slingsby, Brian; Swarbrick, Martin E.; Bioorganic &
     Medicinal Chemistry Letters (2009), 19(23), 6578-6581. CODEN: BMCLE8
     ISSN:0960-894X. CAN 152:97308 AN 2009:1351270 CAPLUS
6.   Identification of [4- [4- (methylsulfonyl)phenyl]- 6- (trifluoromethyl)- 2- pyrimidinyl]
     amines and ethers as potent and selective cyclooxygenase- 2 inhibitors;
     Swarbrick, Martin E.; Beswick, Paul J.; Gleave, Robert J.; Green, Richard H.; Bingham,
     Sharon; Bountra, Chas; Carter, Malcolm C.; Chambers, Laura J.; Chessell, Iain P.; Clayton,
     Nick M.; Collins, Sue D.; Corfield, John A.; Hartley, C. David; Kleanthous, Savvas; Lambeth,
     Paul F.; Lucas, Fiona S.; Mathews, Neil; Naylor, Alan; Page, Lee W.; Payne, Jeremy J.;
     Pegg, Neil A.; Price, Helen S.; Skidmore, John; Stevens, Alexander J.; Stocker, Richard;
     Stratton, Sharon C.; Stuart, Alastair J.; Wiseman, Joanne O.; Bioorganic & Medicinal
     Chemistry Letters (2009), 19(15), 4504-4508. CODEN: BMCLE8 ISSN:0960-894X. CAN
     151:350051 AN 2009:845628 CAPLUS

B. Patents
1. Preparation of piperazine derivatives as cav2.2 calcium channel modulators;
     Beswick, Paul John; Campbell, Alister; Cridland, Andrew Peter; Gleave, Robert James; Heer,
     Jag Paul; Nicholson, Neville Hubert; Page, Lee William ; Vile, Sadie.; PCT Int. Appl.(2010),
     65pp. CODEN: PIXXD2 WO 2010007072 A1 20100121 AN 2010:85019 CAPLUS
2.   Preparation of piperazine derivatives as cav2.2 calcium channel modulators;
     Beswick, Paul John; Campbell, Alister; Cridland, Andrew Peter; Gleave, Robert James; Heer,
     Jag Paul; Nicholson, Neville Hubert; Page, Lee William ; Vile, Sadie.; PCT Int. Appl. (2010),
     111pp. CODEN: PIXXD2 WO 2010007073 A1 20100121 AN 2010:85023 CAPLUS
3.   Preparation of arylpyridazines as cannabinoid CB2 receptor agonists; Gleave,
     Robert; Mitchell, William Leonard; Page, Lee William ; Swarbrick, Martin; Walters, Dewi
     John.; PCT Int. Appl. (2007), 32pp. CODEN: PIXXD2 WO 2007022938 A2 20070301 CAN
     146:274380 AN 2007:227874 CAPLUS.
4.   Preparation of pyridazines as modulators of cannabinoid CB2 receptors; Gleave,
     Robert; Mitchell, William Leonard; Page, Lee William ; Swarbrick, Martin.; PCT Int. Appl.
     (2007), 44pp. CODEN: PIXXD2 WO 2007022937 A1 20070301 AN 2007:227298
     CAPLUS.
5.   Preparation of imidazopyridine derivatives as cannabinoid receptor ligands;
     Eatherton, Andrew John; Giblin, Gerard Martin Paul; Mitchell, William Leonard; Naylor, Alan;
     Page, Lee William ; Swarbrick, Martin; Sweeting, Jennifer Anne.; PCT Int. Appl. (2007),
     58pp. CODEN: PIXXD2 WO 2007017237 A1 20070215 CAN 146:251845 AN
     2007:173985 CAPLUS.

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Publication List

  • 1. Publication List A. Papers 1. The acid mediated intramolecular 1,3- dipolar cycloaddition of 2- Nitro- 1,1 ethenediamine derived nitrile oxides for the synthesis of novel fused bicyclic isoxazoles; Page, Lee W.; Bailey, Matthew.; Beswick, Paul J.; Frydrych Simon.; Gleave, Robert J. for prospective publication in Tetrahedron Letters (with the Editors) 2. The intramolecular amination of allenes; Feast, George C.; Page, Lee W.; Robertson, Jeremy.; "in press" and can be cited as Chem. Commun., 2010, 46, DOI:10.1039/ b926179f 3. Synthesis and evaluation of 3- amino- 6- aryl- pyridazines as selective CB2 agonists for the treatment of inflammatory pain; Gleave, Robert J.; Beswick, Paul J.; Brown, Andrew J.; Giblin, Gerard M. P.; Goldsmith, Paul; Haslam, Carl P.; Mitchell, William L.; Nicholson, Neville H.; Page, Lee W.; Patel, Sadhana; Roomans, Susan; Slingsby, Brian P.; Swarbrick, Martin E.; Bioorganic & Medicinal Chemistry Letters (2010), 20(2), 465-468. CODEN: BMCLE8 ISSN:0960-894X. AN 2009:1591711 CAPLUS 4. An unusual methylene aziridine refined in P21/c and the nonstandard setting P21/n; Feast, George C.; Haestier, James; Page, Lee W.; Robertson, Jeremy; Thompson, Amber L.; Watkin, David J.; Acta Crystallographica, Section C: Crystal Structure Communications (2009), C65(12), o635-o638. CODEN: ACSCEE ISSN:0108-2701. AN 2009:1534462 CAPLUS 5. 2- Amino- 5- aryl- pyridines as selective CB2 agonists: Synthesis and investigation of structure- activity relationships. Gleave, Robert J.; Beswick, Paul J.; Brown, Andrew J.; Giblin, Gerard M. P.; Haslam, Carl P.; Livermore, David; Moses, Andrew; Nicholson, Neville H.; Page, Lee W.; Slingsby, Brian; Swarbrick, Martin E.; Bioorganic & Medicinal Chemistry Letters (2009), 19(23), 6578-6581. CODEN: BMCLE8 ISSN:0960-894X. CAN 152:97308 AN 2009:1351270 CAPLUS 6. Identification of [4- [4- (methylsulfonyl)phenyl]- 6- (trifluoromethyl)- 2- pyrimidinyl] amines and ethers as potent and selective cyclooxygenase- 2 inhibitors; Swarbrick, Martin E.; Beswick, Paul J.; Gleave, Robert J.; Green, Richard H.; Bingham, Sharon; Bountra, Chas; Carter, Malcolm C.; Chambers, Laura J.; Chessell, Iain P.; Clayton, Nick M.; Collins, Sue D.; Corfield, John A.; Hartley, C. David; Kleanthous, Savvas; Lambeth, Paul F.; Lucas, Fiona S.; Mathews, Neil; Naylor, Alan; Page, Lee W.; Payne, Jeremy J.; Pegg, Neil A.; Price, Helen S.; Skidmore, John; Stevens, Alexander J.; Stocker, Richard; Stratton, Sharon C.; Stuart, Alastair J.; Wiseman, Joanne O.; Bioorganic & Medicinal Chemistry Letters (2009), 19(15), 4504-4508. CODEN: BMCLE8 ISSN:0960-894X. CAN 151:350051 AN 2009:845628 CAPLUS B. Patents 1. Preparation of piperazine derivatives as cav2.2 calcium channel modulators; Beswick, Paul John; Campbell, Alister; Cridland, Andrew Peter; Gleave, Robert James; Heer, Jag Paul; Nicholson, Neville Hubert; Page, Lee William ; Vile, Sadie.; PCT Int. Appl.(2010), 65pp. CODEN: PIXXD2 WO 2010007072 A1 20100121 AN 2010:85019 CAPLUS 2. Preparation of piperazine derivatives as cav2.2 calcium channel modulators; Beswick, Paul John; Campbell, Alister; Cridland, Andrew Peter; Gleave, Robert James; Heer, Jag Paul; Nicholson, Neville Hubert; Page, Lee William ; Vile, Sadie.; PCT Int. Appl. (2010), 111pp. CODEN: PIXXD2 WO 2010007073 A1 20100121 AN 2010:85023 CAPLUS 3. Preparation of arylpyridazines as cannabinoid CB2 receptor agonists; Gleave, Robert; Mitchell, William Leonard; Page, Lee William ; Swarbrick, Martin; Walters, Dewi John.; PCT Int. Appl. (2007), 32pp. CODEN: PIXXD2 WO 2007022938 A2 20070301 CAN 146:274380 AN 2007:227874 CAPLUS. 4. Preparation of pyridazines as modulators of cannabinoid CB2 receptors; Gleave, Robert; Mitchell, William Leonard; Page, Lee William ; Swarbrick, Martin.; PCT Int. Appl. (2007), 44pp. CODEN: PIXXD2 WO 2007022937 A1 20070301 AN 2007:227298 CAPLUS. 5. Preparation of imidazopyridine derivatives as cannabinoid receptor ligands; Eatherton, Andrew John; Giblin, Gerard Martin Paul; Mitchell, William Leonard; Naylor, Alan; Page, Lee William ; Swarbrick, Martin; Sweeting, Jennifer Anne.; PCT Int. Appl. (2007), 58pp. CODEN: PIXXD2 WO 2007017237 A1 20070215 CAN 146:251845 AN 2007:173985 CAPLUS.