This document discusses the relationship between personality, stress, and cardiovascular disease. It summarizes several studies that found higher levels of depression, neuroticism, and Type D personality among patients with coronary artery disease compared to healthy controls. Type D personality, characterized by negative affectivity and social inhibition, was found to be more common in patients with coronary artery disease. Stress is identified as a common factor linking depression and cardiovascular disease. The document also discusses the role of context and interpersonal relationships in health, suggesting cardiovascular health and function occurs within social environments and interactions with others.
L'ipertensione polmonare:come diagnosticarla e trattarlaASMaD
Presentazione a cura del Dottor Carmine Dario Vizza - XII° Congresso Nazionale FIMeG 2018 - The Silver Tsunami: l'anziano fra appropriatezza e farmaeconomia
#flozins
🫀DAPA 🆚placebo in HFpEF
Now we have a positive trial!
⬇️18% in CV☠️ death or
worsening HF among LVEF>40%
⬇️ 21%heart failure
💥Results same for LVEF> 60% 🆚LVEF<60%
Drug Treatment of Chronic Coronary Syndrome: Focus Issue on Ranolazinemagdy elmasry
Chronic Coronary Syndromes .Old and New Anti-anginal Drugs.Sodium channel blocker(Ranolazine)Angina / ischaemiac relief .
Voltage-gated sodium channels (NaVChs).Patient profile to guide drug treatment of
chronic coronary syndromes .Therapeutic algorithm for chronic stable angina according to heart rate and blood pressure.Treatment Options for Microvascular angina / Vasospastic angina.Ranolazine in arrhythmias
Ranolazine in ischemic reperfusion injury
Ranolazine in pulmonary hypertension
Ranolazine in heart failure
Ranolazine in the prevention of chemotherapy‑induced cardiotoxicity
Role in diabetes mellitus
Ranolazine in peripheral arterial disease
Ranolazine in myotonia‑congenita
Ranolazine in hypertrophic cardiomyopathy.Antiarrhythmic properties of ranolazine.Amiodarone +Ranolazine
Niklas Nielsen talks about the TTM trial as seen through a 2019 lens.
The video and references from the talk and all the rest of the goodness from The Big Sick 2019 in Zermatt is up at
https://scanfoam.org/
Depresi dan bunuh diri sebagai masalah kesehatan mental yang lazim untuk pasien hemodialisis. Tujuan: Para penulis meneliti faktor-faktor demografi dan psikologis yang terkait dengan depresi pada pasien hemodialisis dan dijelaskan hubungan antara depresi, kecemasan, kelelahan, kualitas kesehatan yang berhubungan hidup yang buruk, dan meningkatkan risiko bunuh diri.
L'ipertensione polmonare:come diagnosticarla e trattarlaASMaD
Presentazione a cura del Dottor Carmine Dario Vizza - XII° Congresso Nazionale FIMeG 2018 - The Silver Tsunami: l'anziano fra appropriatezza e farmaeconomia
#flozins
🫀DAPA 🆚placebo in HFpEF
Now we have a positive trial!
⬇️18% in CV☠️ death or
worsening HF among LVEF>40%
⬇️ 21%heart failure
💥Results same for LVEF> 60% 🆚LVEF<60%
Drug Treatment of Chronic Coronary Syndrome: Focus Issue on Ranolazinemagdy elmasry
Chronic Coronary Syndromes .Old and New Anti-anginal Drugs.Sodium channel blocker(Ranolazine)Angina / ischaemiac relief .
Voltage-gated sodium channels (NaVChs).Patient profile to guide drug treatment of
chronic coronary syndromes .Therapeutic algorithm for chronic stable angina according to heart rate and blood pressure.Treatment Options for Microvascular angina / Vasospastic angina.Ranolazine in arrhythmias
Ranolazine in ischemic reperfusion injury
Ranolazine in pulmonary hypertension
Ranolazine in heart failure
Ranolazine in the prevention of chemotherapy‑induced cardiotoxicity
Role in diabetes mellitus
Ranolazine in peripheral arterial disease
Ranolazine in myotonia‑congenita
Ranolazine in hypertrophic cardiomyopathy.Antiarrhythmic properties of ranolazine.Amiodarone +Ranolazine
Niklas Nielsen talks about the TTM trial as seen through a 2019 lens.
The video and references from the talk and all the rest of the goodness from The Big Sick 2019 in Zermatt is up at
https://scanfoam.org/
Depresi dan bunuh diri sebagai masalah kesehatan mental yang lazim untuk pasien hemodialisis. Tujuan: Para penulis meneliti faktor-faktor demografi dan psikologis yang terkait dengan depresi pada pasien hemodialisis dan dijelaskan hubungan antara depresi, kecemasan, kelelahan, kualitas kesehatan yang berhubungan hidup yang buruk, dan meningkatkan risiko bunuh diri.
lecture 27 from a college level introduction to psychology course taught Fall 2011 by Brian J. Piper, Ph.D. (psy391@gmail.com) at Willamette University, Seyle
Negative emotion and health why do we keep stalking bears, when we only find ...James Coyne
Describes the frustrating search for a link between specific negative emotions and health and why the search often fails. Integrates epidemiology and psychology.
Journey to posttraumatic stress disorder Sajia Iqbal
Journey to PTSD covers what PTSD is, its symptoms, its severe conditions in globe, some theoritical causes leading PTSD, models' strength and weakness.
DEPRESIJA – značaj teme
On behalf of the course Co-Directors Profs. Geoffrey Reed and Mario Maj, we wish to thank you again for your participation in the ICD-11 Diagnostic Guidelines for Mental, Behavioural and Neurodevelopmental Disorders: An Online Comprehensive Course for Psychiatrists.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
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This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
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Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
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NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
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11. “The literature review on which this chapter
is based was originally conducted in the
context of the Psychocardiology Status
Conference.
Between 1998 and 2002, the members of
this panel wrote comprehensive reviews of
psychosocial aspects of CHD and met
several times a year to discuss and peer
review their work (Jordan, Barde, & Zeiher,
2001)”.
13. Type D Personality
Negative Affectivity Social Inhibition
Definition
tendency to experience negative emotions
across time/situations
tendency to inhibit emotions and behaviors
in social interaction
Manifestation
unhappy, tends to worry;
easily irritated;
closed and reserved;
tends to keep others at distance
Assessment DS14 subscale (7 items; ≥ 10 cut-off) DS14 subscale (7 items; ≥10 cut-off)
Sample items
“I often feel unhappy”
“I often find myself worrying about something”
“I am often irritated”
“I am a closed kind of person”
“I often feel inhibited in social interactions”
“I find it hard to start a conversation”
Pedersen & Denollet, 2006
14. Old wines, new bottles
Stress
Personality
Heart
Depression vs. Negative affectivity
Stable personality traits vs. Current state
Interpersonal Communication Context
15. Relationship between depression and
coronary heart disease
Olivera Vukovic1, Dušica Lecic-Toševski2, Jelena Stepanovic3
1 Institute of psychiatry, CCS 2 Institute for mental health; 3Institute of cardiovascular diseases
UVOD: Klinička depresija ne dovodi isključivo do gubitka zadovoljstva u svakodnevnim aktivnostima već komplikuje, a najverovatnije
predstavlja i faktor rizika za razvoj koronarne bolesti (KB). Predloženo je više mehanizama kojima se tumači priroda medjuodnosa ova
dva poremećaja. Cilj studije bio je da se ispita nivo depresivnosti i učestalost tipa D ličnosti kod pacijenata sa dijagnozom stabilne
koronarne bolesti u odnosu na kontrolnu grupu zdravih ispitanika.
• grupa 1 = 36 subjekata sa dijagnozom stabilne KB
muškarci 18 (50%); starost 55,34 (SD 7,32)
• grupa 2 = 30 zdravih subjekata
muškarci 24 (80%); starost 52,10 (SD 6,86)
REZULTATI I DISKUSIJA:
Instrumenti procene:
• Skala depresije, anksioznosti i stresa (DASS)
• D14 upitnik (DS14):
METOD:
0
20
40
60
80
non Tip D Tip D
grupa 1 grupa 2
Na osnovu iznetih rezultata pokazano je da su negativne emocije udružene sa KB. Stres predstavlja
zajednički imenitelj depresije i KB, te pretpostavljamo da udruženost ova dva poremećaja posreduje,
izmedju ostalih i specifična konstelacija ličnosti, tzv. ličnost sklona distresu (tip D ličnosti).
**
U grupi 1, prosečna vrednost subskale depresivnost DASS skale je statistički značajno viša u odnosu na srednju vrednost u grupi 2 (17,34±8,50 nasuprot 8,80±5,83;
p<0.01). Potvrdjeno je da postoji različita učestalost tipa D ličnosti u ispitivanim grupama. Naime, 24 (66,73%) ispitanika grupe 1 zadovoljava kriterijume za tip D
ličnosti, dok je u grupi 2 učestalost tipa D bila statistički značajno manja 12 (40.0%) (χ2[1]=4,69; p<0.05). U obe ispitivane grupe, vrednosti DASS i DS-14 visoko
koreliraju (u grupi 1 r=.746; p<0.01; u grupi 2 r=.761; p<0.01).
16.
17. Percentage of distressed CAD patients (n=79), stratified by depressive disorder and Type
D personality
41,2%
12,9%
58,8%
0
10
20
30
40
50
60
70
Depressed Type D Depressed non-Type D Non-Depressed Type D
Distressedpost-MIpatients(%) Type D personality in patients with coronary
artery disease, 2
Vukovic O, et al., Psychiatr Danub, 2014.
20. Figure 2. Resting and peak values of heart rate, systolic and diastolic blood pressure, and rate-pressure product in patients who developed myocardial ischemia (positive)
and who did not develop myocardial ischemia (negative) during mental stress (MS) test (math and anger recall). b/min = beats per minute.
21.
22. Blood pressure reactivity from
resting baseline to task
F[2,77]=4,11; p=0,04; partial η2=0,19 F[1,77]= 1,41; p=0,23; η2=0,007
Condition: 1 = Baseline period, 2 = Rest, 3 = Mental arithmetic task, 4 = Anger recall task.
p=0,01
p =0,003
p=0,03
p=0,00
Vukovic O, et al. 2011.
23.
24. Potencijali
Ljudi poseduju osobine koje se
mogu ostvariti samo u okviru
određjenih sredina, koje mogu
ali i ne moraju biti deo njihove
svakodnevice!!!
Psihološki kvaliteti nisu
inherentne karakteristike, već
zahtevaju socijalno okruženje da
bi se ispoljili
Kaganova (1998) analogija
Kategorija potencijalno opasnih objekata
25. Contextual cardiology
Interpersonal cardiovasular systems
Health is an interpersonal matter, and heart develops
and functions in interaction with other hearts
Should our understanding, diagnosis, and treatment
of the cardiovascular system be done in the context
of our patients’ interpersonal interactions?
It seems possible that these styles, particularly in the
context of interpersonal relationships, could have a
significant impact on the cardiovascular system.
Pearsall, 2007
26. Health in context
“I ka `olelo no ke ola
I ka `olelo no ka make”
“Our words bring life, our
words cause death”
Smith et al. 2012
27. Broken heart syndrome
First report of tako-tsubo cardiomyopathy -
Takotsubo-like left ventricular (LV)
dysfunction described by Dr Sato (Satoh et
al., 1990.) Increase in the Number of Publications on
MEDLINE Concerning Takotsubo Cardiomyopathy
28.
29.
30. Happy heart syndrome
Patient 1 Birthday party
Patient 2 Son's wedding
Patient 3 Meeting after 50 years with friends from high school
Patient 4 Preparing 50th wedding anniversary (pleasant anticipation)
Patient 5 Positive job interview
Patient 6 Wedding
Patient 7 Favourite driver won race car competition
Patient 8 Becoming grandmother
Patient 9 Surprise farewell celebration
Patient 10 Son's company opening
Patient 11 Favourite rugby team won game
Patient 12 Emotional speaking during a friend's birthday
Patient 13 Celebrating 80th birthday
Patient 14 Winning several jackpots at the casino
Patient 15 Celebration of normal PET-CT scan
Patient 16 Visiting opera with her family
Patient 17 Family party
Patient 18 Unexpected visit from favourite nephew
Patient 19 Grandchildren visiting from London (abroad)
Patient 20 Becoming great grandmother
31. The SAGE Handbook of Personality
and individual differences
Stress and its multiple faces
Dusica Lecic Tosevski2, 3, Olivera Vukovic1,2, Bojana Pejuskovic1,2, Nadja P. Maric1,4
1 School of Medicine, University of Belgrade, Belgrade, Serbia
2 Institute of Mental Health, Belgrade, Serbia
3 Serbian Academy of Sciences and Arts
4 Clinic for Psychiatry, Clinical Center of Serbia, Belgrade, Serbia
Zeigler-Hill, V., & Shackelford, T. K. (in press). The SAGE handbook
of personality and individual differences: Volume 3. Applications
of personality and individual differences. London: SAGE.
Editor's Notes
Note: Depression: assessed by the BDI > 10; Type D: assessed by the DS14 scale (NA ≥ 10 and SI ≥10).
Marital Discord and Coronary Artery Disease - prospektivna studija sprovedena na University of Utah u periodu od 2002 do 2005 koja je obuhvatila 150 bračnih parova, životne dobi od 60 do 70 godina bez istorije srčane bolesti
6-minutna verbalnu interakciju izmedju bračnih parova o temama oko kojih se parovi nisu slagali i procenjivali ... dva dana kasnije, oba supružnika su radila CT grudnog koša i nalazi ilustruju šta se može nauliti o srcima u kontekstu interpesonalnih veza u kojima oni egzistiraju (tzv. “naupaka efekat”).
komentari hostilnih supruga (žena!) (npr “Ponekad si neverovatn glup”), veći stepen/obim kalcifikacija ili „krtost“ njihovih kardiovaskularnih arterija. Pogotovo visok nivo kalcifikacije nadjen je kod žena koje su govorile na hostilan način tokom interakcije sa supružnicima koji su odgovarali takodje na hostilan način.
rečenice kontrolišućih žena i muževa (npr. “Uradiću ono što želiš, da te skinem sa kičme ”), veći stepen kalcifikacije u koronarnim k.s. muževa. Istraživači su zaključili da hostilne reči tokom bračne rasprave dovode do veće kalcifikacije koronarni žena Kontrolišuće reči tokom nesuglasica dovode do kalcifikacije u koronarkama muževa, ali ne i žena.