Overview Clinical Presentation Diagnosing Psoriasis Managing Psoriasis Case Studies

1. Psoriasis
Stem Cell Therapy
in
DR. SHARDA JAIN
Dr. Jyoti Aggarwal
Dr. Rashmi Jain
Dr.Indu Tyagi

2. Overview
4. Case Studies
3. Managing Psoriasis
2. Diagnosing Psoriasis
1. Clinical Presentation

4. What is Psoriasis?
–Inflammatory and hyperplastic disease
of skin
–Characterised by erythema and elevated
scaly plaques
–Chronic, relapsing condition
–Course of disease often unpredictable
but very demoralising to patient
.

5. psoriasis is an immune
system disorder but
also think that genetics
and the environment
contribute to flare-ups.
There are several
triggers that can make
psoriasis worse.

6. 5
19
21
29
31
71
79
94
0 10 20 30 40 50 60 70 80 90 100
Other
Fatigue
Burning sensation
Bleeding
Tightness of skin
Skin redness
Itching
Scaling
Percentage of respondents (n = 17,425)
Symptoms of psoriasis
6
Most frequently
experienced symptoms

7. Psoriasis affects emotional state
54
75
81
88
0 20 40 60 80 100
Depression
Feelingsof unattractiveness
Feelingsof embarrassment
Concernthat disease would
worsen
Percentage of 18-to-34-year-old respondentswith severe psoriasis

8. Prevalence
3-5% of Population
Any age
Both sexes equally Affected
1/3 present before 20yrs
Incidence-Underestimated

9. Common trigger factors for
Psoriasis
• Infections (e.g. streptococcal, viral)
• Skin trauma (Koebner phenomenon)
• Psychological stress
• Drugs (e.g. lithium, beta blockers)
• Sunburn
• Metabolic factors (e.g. calcium deficiency)
• Hormonal factors (e.g. pregnancy)

10. Clinical presentation:
Classic psoriasis
–Well-defined and
sharply demarcated
–Round/oval-shaped
lesions
–Usually symmetrical
–Erythematous,
raised plaques
–Covered by white,
silvery scales

11. Common sites
• Can affect any
part of the body –
typically scalp,
elbow, knees and
sacrum
• Extent of disease
varies

12. Types of psoriasis
• Chronic plaque
• Guttate
• Flexural
• Erythrodermic
• Pustular
–Localised and generalised
• Local forms
–Palmoplantar
–Scalp
–Nail (psoriatic
onychodystrophy)

13. 13
Chronic Plaque Psoriasis

18. Guttate psoriasis
– Numerous and
small lesions – ~ 1
cm diameter
– Pink with less scale
than plaque
psoriasis
– Commonly found on
trunk and proximal
limbs
1. 18

19. Flexural psoriasis
– Lesions in skin folds
articularly groin,
gluteal cleft, axillae
and submammary
regions
– Often minimal or
absent scaling

20. Erythrodermic psoriasis
– Generalised
erythema covering
entire skin surface
– Complications
include cardiac
failure, infections,
malabsorption and
anaemia
– Relatively
uncommon

21. Pustular psoriasis
–Two forms:
• Localised form
• Generalised form

22. Palmoplantar psoriasis
–Can be
hyperkeratotic
or pustular

23. Scalp psoriasis
– May extend beyond
hairline
– Patient scratching
may produce
asymmetric plaques

24. Nail psoriasis

25. 75% of people experience
mild disease that can be
treated effectively with
Topical Therapy.
Psoriasis

26. Systemic Agents-Methotrexate
• To suppress Immune system
• Well tolerated & safe for long
term maintainance dose in
Moderate & Severe Plaque
Psoriasis.

27. Tremendous Negative
Impact on quality of life of
both the Patient & Family
in Moderate & Severe
diseases.
Psoriasis

28. Profound Psychological Distress
Significant Depression
A High rate of thought
about Suicide

29. Co-morbidities
• 2/3 Severe Cases have atleast two
Co-morbidities
• Cardiovascular Diseases
Hypertention
Dislipedemia & CAD
• Psoriatic Arthiritis
• Crohn’s Diseases /Ulcerative Colitis
30%
30%
30%

30. There is
for PSORIASIPsoriasis

31. TOPICAL AGENTS
are typically used in mild
diseases which account
for nearly ¾ cases.

32. Stem Cell Therapy
is showing promise in
Auto-ImmuneDisorders
&
Severe Psoriasis
Resistant
to Conventional Treatment

33. HOW Does Stem
Cell Therapy Act
By Para Crine Effect
& Immuno modulation

34. SATISFIED CLIENT
Dr.Raghavan
(President of World
Ayurvedic Association)
-Arthiritis
-Psoriasis
Had a Bad Disease in
Legs, Back & Elbow joints

35. Madam I am 60%
Better and I never
enjoyed such good
sleep which I am
having now
-Dr.Raghavan (1st Oct.15)

36. SATISFIED CLIENT
Anu Bansal
(Teacher)
-Psoriasis
-Psoriatic Arthirits

40. MERA PAISA
VASOOL HOGAYA
-GOD BLESS YOU
DR.JAIN

41. SATISFIED CLIENT
Dr.Lakshmi Devi
-Psoriasis
-Anti-Ageing

42. BEFORE
Amazing Relief
-Dr.Lakshmi

43. SATISFIED CLIENT
Dr.Aggarwal (37yrs)
-Psoriasis
-Arthirits Hand & Toes

44. Dr.Aggarwal

45. UNBELIEVABLE
Relief
HOPE it LASTS
-Dr. Aggarwal

46. UNBELIEVABLE
RESULTS
You need, your own Experience

47. A bright future awaits you….
take the first step !
Are you ready
for a major break through
in your life ?
Safety : All are Great Gurus

48. ISO 14001:2004 (EMS)
…..Caring hearts, healing hands
ISO 9001:2008
HELPLINE-9650588339/
22414049
HELPLINE-9599044257
HELPLINE-9910081484
ISO 9001:2008
HELPLINE
9599044357