Addiction is characterized as a chronic disease involving the brain's reward system and impaired ability to control behaviors. Anyone can become addicted depending on risk factors like stress, family history, self-esteem, exposure to drugs, and mental illness. The spectrum of substance use ranges from abstinence to severe addiction. Drugs affect the brain stem, limbic system, and cortex to produce effects like depression, aggression, and impaired thinking. Teenage brains are still developing and vulnerable to long-term effects of drugs on memory, health, and life outcomes like poor academic or job performance and relationship issues. Tobacco and alcohol are the most commonly abused substances among youth and pose serious health risks. Avoiding drugs and smoking is important