This document discusses issues of alienation and disconnection in adolescence. It describes forms of alienation such as normlessness, powerlessness, social isolation, and meaninglessness. Adolescents who are poor and minority experience the greatest alienation. Being faced with responsibility but lacking authority can lead to disconnectedness. Outcomes of alienation may include internalizing problems like anxiety and depression or externalizing problems like aggression. Substance abuse is discussed as a form of self-medication for emotional distress.