Digital and offset printing are the two main types of professional printing. Digital printing prints directly from digital files onto paper without plates, while offset printing uses plates to transfer ink from a plate to a rubber blanket to paper. Offset is best for larger print runs due to lower per-unit costs, while digital is faster with on-demand printing and customization. The offset printing process involves pre-press work to create plates from digital files, running the plates through a printing press, and finishing steps like trimming, folding and binding. Proper file preparation for offset includes using CMYK color, high resolution images, correct bleed and trim settings.