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Chitosan: Synthesis, Properties and Applications Author: Teo Shi Yu Kenvin, 061932E07 Chitosan Chitosan is a  linear polysaccharide  composed of randomly distributed  β-(1-4)-linked D-glucosamine ( deacetylated unit ) and N-acetyl-D-glucosamine ( acetylated unit ).  Figure 1: Chemical structure of Chitosan. (C 6 H 11 O 4 N) n   Synthesis of Chitosan  ,[object Object],[object Object],[object Object],Chitosan is produced commercially by  deacetylation  of  chitin, which is the structural element in the exoskeletons of crustaceans. Figure 2: Deacetylation of chitin includes the removal of CH 3 CO group Properties of Chitosan The amino group in chitosan is positively charged and readily binds to negatively charged surfaces such as mucosal membranes.  ,[object Object],[object Object],[object Object],Chitosan has the quality of not having toxic or injurious effects on biological systems and it is an organic compound that can be broken down by a living body. ,[object Object],Applications of Chitosan ,[object Object],Chitosan is used in making of bandages and hemostatic agents due to its ability of clotting blood rapidly. Trimethylchitosan is used to transfect breast cancer cells and efficient in non viral gene delivery.  ,[object Object],Derivatives of chitosan, Trimethylchitosan is able to introduce foreign material into eukaryotic cells. i.e. gene delivery function ,[object Object],[object Object],Chitosan is used as seed coating and plant growth enhancer. ,[object Object],Chitosan is used as active mud coagulant, adhesive, adsorbent of the heavy metal ion and organic compound. ,[object Object],It improves flocculation and is used in filtration processes. It is also used as a  subsidiary material of the color fixer, patternizer, adhesive and stabilizer in plastic industry

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Poster Design for Polymers and Composite

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