This document summarizes different drug classes used to treat gastrointestinal issues. It outlines several classes of drugs including antacids, H2 receptor antagonists, GI prostaglandins, proton pump inhibitors, prokinetic agents, and antispasmodic agents. For each class, it lists examples of specific drugs and common side effects. The potential serious side effects of some drugs are also mentioned.

1. Pharmacology II
Chapter 33

2. Drug Classes
• Antacids
• H2 Receptor Antagonists
• GI Prostaglandins
• Proton Pump Inhibitors
• Prokinetics Agents
• Antispasmodic Agents

3. Antacids
• Aludrox
• Baking soda
• Di-Gel
• Gelusil
• Maalox
• Mylanta
• Phillips Milk of Magnesia
• Rioopan
• Titralac
• Tums

4. H2 Receptor Antagonists
• Cimetidine Tagmet
• Ranitidine Zantac
• Nizatidine Axid
• Famotidine Pepcid
• Dizziness headache somnolence
• Diarrhea constipation
• SERIOUS: confusion, disorientation,
hallucination, gynecomastia Hepatoxicity!

5. GI Prostaglandins
• Misoprostol Cytotec
• Diarrhea dose related after 2 wks. of therapy
– Minimized by taking with meals, avoid Mg+
antacids, & @ bedtime
• Pregnancy

6. Proton Pump Inhibitors
• Esomeprazole Nexium
• Lansoprazole Prevacid
• Omeprazole Prilosec
• Pantoprazole Protonix
• Rabeprazole Aciphex
• Constipation dry mouth dizziness

7. Prokinetic Agents
• Metoclopramide Reglan
• Drowsiness fatigue lethargy dizziness
• SERIOUS: Extrapyramidal symptoms

8. Antispasmodic Agents
• Atropine
• Belldonna
• Dicyclomine Bentyl
• Glycopyrrolate Robinul
• Mepenzolate Cantil
• Methscopolamine Pamine
• Propantheline Pro-Bathine
• Scopolamine Scopace
• Blurred vision constipation urinary retention dry mouth,
nose, throat
• SERIOUS: confusion, depression, nightmares, hallucinations
• Orthostatic hypotension!!