Pharmacognosy is the study of biologically active compounds found in plants and animals, many of which have been used for thousands of years in traditional medicine and now form the basis for modern pharmaceuticals. Approximately 25% of medications originate from natural sources. Secondary metabolites produced by organisms often serve defensive functions but can have pharmacological effects in humans when isolated and dosed properly, such as hypericin from St. John's Wort for mood enhancement, echinacoside from Echinacea for immunity, and digoxin from foxglove to regulate heart rhythm. While isolated compounds allow for mass production and standardization, crude plant and animal materials may provide synergistic effects from multiple constituents.
Natural products as a crucial source of anti-inflammatory drugs: recent trend...LucyPi1
Abstract Natural active molecules are key sources of modern innovative drugs. Particularly, a great amount of natural active molecules have been reported to possess promising therapeutic effects on inflammatory diseases, including asthma, rheumatoid arthritis, hepatitis, enteritis, metabolic disorders and neurodegenerative diseases. However, these natural active molecules with various molecular structures usually exert anti-inflammatory effects through diversiform pharmacological mechanisms, which is necessary to be summarized systematically. In this review, we introduced the current major anti-inflammatory natural active molecules based on their chemical structures, and discussed their pharmacological mechanisms including anti-inflammatory molecular signaling pathways and potential target proteins, which providing a referential significance on the development of novel anti-inflammatory drugs, and also revealing new therapeutic strategies for inflammatory diseases.
Pharmacology An Introduction 6th Edition Hitner Test BankMichaelMichaelss
Full download : http://alibabadownload.com/product/pharmacology-an-introduction-6th-edition-hitner-test-bank/ Pharmacology An Introduction 6th Edition Hitner Test Bank
Natural products as a crucial source of anti-inflammatory drugs: recent trend...LucyPi1
Abstract Natural active molecules are key sources of modern innovative drugs. Particularly, a great amount of natural active molecules have been reported to possess promising therapeutic effects on inflammatory diseases, including asthma, rheumatoid arthritis, hepatitis, enteritis, metabolic disorders and neurodegenerative diseases. However, these natural active molecules with various molecular structures usually exert anti-inflammatory effects through diversiform pharmacological mechanisms, which is necessary to be summarized systematically. In this review, we introduced the current major anti-inflammatory natural active molecules based on their chemical structures, and discussed their pharmacological mechanisms including anti-inflammatory molecular signaling pathways and potential target proteins, which providing a referential significance on the development of novel anti-inflammatory drugs, and also revealing new therapeutic strategies for inflammatory diseases.
Pharmacology An Introduction 6th Edition Hitner Test BankMichaelMichaelss
Full download : http://alibabadownload.com/product/pharmacology-an-introduction-6th-edition-hitner-test-bank/ Pharmacology An Introduction 6th Edition Hitner Test Bank
Toxicology
Principles of Toxicology
Dose-response relationship
Risk = Hazard X Exposure
Factors that influence toxicity
Drug Toxicology
Therapeutic index
Therapeutic window
Idiosyncrasy
Pharmcogenetics
Drug allergy
Test for prediction drug allergy
Toxicology is a branch of biology, chemistry, and medicine that concerned with the study of the adverse effects of chemicals on living organisms.
Introduction of Pharmacognosy, Scope and Traditional system of MedicineSHIVANEE VYAS
The term Pharmacognosy comes from two Greek words: “Pharmakon" meaning drug or medicine, and "gnosis" meaning knowledge or study. Pharmacognosy also defined as the systemic study of crude drugs obtained from natural origin like plants, animals, minerals, and microbes. Pharmacognosy defined as the branch of science which involves details study of drug obtained from natural origin including name, collection, cultivation, macroscopy, microscopy, physical property, chemical constituents, therapeutic action and uses.
https://youtu.be/gxOVfntCCB8
ReMiND Pilot Project - strengthening ASHA performance through improved superv...mhensley_CRS
Catholic Relief Services partners with Dimagi Inc. and Vatsalya to implement the Reducing Maternal and Newborn Deaths (ReMiND) Pilot Project in 2 blocks of Kaushambi District in Uttar Pradesh (India). ReMiND has pioneered a supervision approach that uses Dimagi's CommCare technology and active use of real-time data generated from community health workers' and supervisors' use of mobile phones to improve the quality and timeliness of government community health workers' (called ASHAs) home visits to pregnant women, newborns and young children.
Toxicology
Principles of Toxicology
Dose-response relationship
Risk = Hazard X Exposure
Factors that influence toxicity
Drug Toxicology
Therapeutic index
Therapeutic window
Idiosyncrasy
Pharmcogenetics
Drug allergy
Test for prediction drug allergy
Toxicology is a branch of biology, chemistry, and medicine that concerned with the study of the adverse effects of chemicals on living organisms.
Introduction of Pharmacognosy, Scope and Traditional system of MedicineSHIVANEE VYAS
The term Pharmacognosy comes from two Greek words: “Pharmakon" meaning drug or medicine, and "gnosis" meaning knowledge or study. Pharmacognosy also defined as the systemic study of crude drugs obtained from natural origin like plants, animals, minerals, and microbes. Pharmacognosy defined as the branch of science which involves details study of drug obtained from natural origin including name, collection, cultivation, macroscopy, microscopy, physical property, chemical constituents, therapeutic action and uses.
https://youtu.be/gxOVfntCCB8
ReMiND Pilot Project - strengthening ASHA performance through improved superv...mhensley_CRS
Catholic Relief Services partners with Dimagi Inc. and Vatsalya to implement the Reducing Maternal and Newborn Deaths (ReMiND) Pilot Project in 2 blocks of Kaushambi District in Uttar Pradesh (India). ReMiND has pioneered a supervision approach that uses Dimagi's CommCare technology and active use of real-time data generated from community health workers' and supervisors' use of mobile phones to improve the quality and timeliness of government community health workers' (called ASHAs) home visits to pregnant women, newborns and young children.
The quality and efficacy of Traditional Herbal Medicine can be influenced by correct collection of Raw Materials. In this presentation prepared by Dr. Eugene Zampieron, ND, we discuss collection details to assure the best quality and efficacy of traditional herbal remedies made at home. Tinctures, Extracts, Poultices, Salves and other Herbal Preparations are discussed.
The IOSR Journal of Pharmacy (IOSRPHR) is an open access online & offline peer reviewed international journal, which publishes innovative research papers, reviews, mini-reviews, short communications and notes dealing with Pharmaceutical Sciences( Pharmaceutical Technology, Pharmaceutics, Biopharmaceutics, Pharmacokinetics, Pharmaceutical/Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmacognosy & Phytochemistry, Pharmacology, Pharmaceutical Analysis, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics and Biotechnology of Pharmaceutical Interest........more details on Aim & Scope).
All manuscripts are subject to rapid peer review. Those of high quality (not previously published and not under consideration for publication in another journal) will be published without delay.
Pharmacognosy is "the study of the physical, chemical, biochemical and biological properties of drugs, drug substances or potential drugs or drug substances of natural origin as well as the search for new drugs from natural sources".
This presentations includes information about definition of pharmacology, history, nature and sources of drugs, different terms used in Pharmacology, Essential Drugs concept, Routes of Drug Administration, and Agonist and Antagonist.
American Journal of Multidisciplinary Research and Development is indexed, refereed and peer-reviewed journal, which is designed to publish research articles.
Pharmacological Applications of Isorhamnetin: A Short Reviewijtsrd
Isorhamnetin (30-Methoxy-3, 40, 5, 7-tetrahydroxyflavone) is a flavonol, and it belongs to a group of plant secondary metabolites known as flavonoids. It is present in mans daily diet and is known for its biological activities such as antioxidant, antiviral, anticancer, antimicrobial, and anti-inflammatory effects. Isorhamnetin has been reported for its antioxidant and antiviral applications hence it is not only used as such, but it also has various derivatized forms which has potentials for development into drugs for the treatment of diseases caused by oxidative stress and lethal viruses. The present review reflects the pharmacological importance of isorhamnetin. S Kandakumar | Dr V Manju"Pharmacological Applications of Isorhamnetin: A Short Review" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-1 | Issue-4 , June 2017, URL: http://www.ijtsrd.com/papers/ijtsrd2202.pdf http://www.ijtsrd.com/biological-science/biochemistry/2202/pharmacological-applications-of-isorhamnetin-a-short-review/s-kandakumar
Pharmacological Applications of Isorhamnetin: A Short Review
Pharmacognosy
1. Pharmacognosy
Perhaps 25% of all pharmaceutical medications have their origin in natural materials obtained from
plants and animals. For thousands of years, cultures throughout the world have passed down
knowledge regarding the use of these materials in the management of disease and optimal health.
Often, this knowledge was transferred in oral traditions, from one generation to the next.
The Emerging Science of Pharmacognosy
Over the past century, advances in chemistry detroit real estate agent and refined research
procedures have allowed for the intense analysis of plant and animal materials for biological activity.
Constituents may now be identified, isolated, and then examined objectively. This field of study
which includes traditional use and pharmacological activity is termed pharmacognosy.
Organisms Create Chemicals for Activities like Defense
These compounds are usually classified as secondary metabolites. Secondary metabolites are
chemicals that don't directly participate in the metabolism of an organism but provide important
functions like defense. For instance, nicotine, an alkaloid from tobacco plants (Nicotiana attenuata)
appears to poison herbivores that eat it, suppressing their growth and decreasing lifespan.
These secondary metabolites may elicit positive effects in the treatment of health conditions when
dosed adequately.
Secondary Metabolites have Pharmacological Effects
2. Secondary metabolites from plants and animals often have diverse effects on other living organisms.
Some examples include:
Hypericin: anthroquinone derivative of St John's Wort (Hypericum perforatum), immunity and mood
enhancement
Echinacoside: phenylethanoid found in various Echinacea species, immune enhancement
Azadirachtin: tetratriterpenoid derivative of neem (Azadirachta indica), inhibits feeding of various
insects
Digoxin: cardiac glycoside of foxglove (Digitalis purpurea), regulates rhythm and strengthens beat of
heart
Exendin-4: a hormone-like protein derived from Gila monster (Heloderma suspectum) saliva,
hypoglycemic effects
Isolated Compounds verses Crude Materials
Crude materials are a complex mix of chemical compounds with varying and often synergistic
effects. Controversy exists regarding the use of isolated compounds verses crude forms of materials.
Proponents of isolated constituents often speak on the varying potency and relative scarcity of plants
and animals. Other complexities impacting the use crude materials include adulteration, use of
wrong species, and improper harvesting procedures. Isolated compounds often may be mass
produced using organisms or laboratory methods.
Opponents of isolated constituents point to the increased chance of adverse effects when using
isolated compounds, and the synergistic effects associated with the soup of constituents in crude
materials.
Sources:
Bond, "Exenatide (Byetta) as a novel treatment option for type 2 diabetes mellitus," Baylor
University Medical Center Proceedings 19, no. 3 (July 2006): 281-4.
Brockman, H. et al. 1939 Hypericin, the photodynamically active pigment from Hypericum
perforatum. Naturwiss.27:550-555
Edith Beckmann Gemma E. Veitch and Gemma E. Veitch, Edith Beckmann, Brenda J. Burke, Alistair
Boyer, Sarah L. Maslen, Steven V. Ley, "Synthesis of Azadirachtin: A Long but Successful Journey,"
Angewandte Chemie International Edition 46 (2007): 7629.
Goodman, RM Rossen, DS Cannom, AK Rider and DC Harrison, "Effect of digoxin on atioventricular
conduction." Circulation 1975;51;251-256
Yu Wu et al., "Protective effects of echinacoside on carbon tetrachloride-induced hepatotoxicity in
rats," Toxicology 232, no. 1-2 (March 22, 2007): 50-56.
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