This document discusses the layout of a pharmaceutical plant. It describes two main types of plant layouts: process/functional layout and product/straight line layout. It also lists factors that influence plant layout decisions such as type of process, space availability, and health and safety considerations. The document provides details on storage space requirements for raw materials, finished goods, and specialized storage facilities. It concludes with a brief section on sterile or aseptic area layout in pharmaceutical plants.

1. PRESENTED BY:
EHTESHAM
1422750 (QA)
MMCP
PHARMACEUTICAL PLANT
LAYOUT
PRESENTED
TO:-
DR MANISH
MMCP

2. INTRODUCTION:
Plant layout involve the location of
different department and
arrangement of machinery in each
department.
Plant layout involve the location of
different department and
arrangement of machinery in each
department.
Potential problems could be
analyzed rapidly and an alternative
solution could be found.

4. TYPES OF PLANT LAYOUT:
A.PROCESS LAYOUT OR FUNCTIONAL LAYOUT:
Functional layout are
arrangement of machines of a
particular class doing a particular
type of work or process as a
separate department.
B. PRODUCT OR STRAIGHT LINE LAYOUT:
product layout are arragement of
machine doing various operation in
a line as one department.

5. FACTOR INFLUENCING PLANT
LAYOUT:
1.Type of process and product
control:smooth and continuous
flow in the process is
desirable.The layout should be
flexible.
2. Operational convenience:-
Facilities(machinery,raw
material)are integrated in a
logical and balanced manner.

6. 3. Space available and space
required:-boxes and bags
contaning raw material and
good can be stacked one above
the others.This is essential for
warehouse.
4.Types of building:-Depending
on the space,the choice

7. 5.Helath and safety
consideration:-workin space
shold be safe,well ventilated
and free from dust,noise,fumes.
6.Waste disposal problems.

8. STORE SPACE
REQUIREMENTS:-
A.Store-Location:-Ideally, the
stores should be located
adjusted to the manufacturing
area and finished goods nearer
to the shipping area,so that
handling costs will be minimum.

9. Advantages:-
Stores has better supervision
and control.
It requires less personnel to
manage and involve reduced
cost.
Better layout of stores can be
planned

10. GENERAL STORE SPACE
REQUIREMENTS:-
1.Adequate storage for raw
material,intermediate
product,recycle material and
fuels are essential for the a
processing plant.
2.Adequate space facilities for
stocking incoming raw
material,for their

11. SPECIAL STORAGE SPACE
FACILITIES:-
I. Special product that require
low temperature
storage,special conditions
such as cool place,cold
storage,freeze etc are provide.
II. Highly toxic and dangerous
substance.
III. Narcotic drug and alcohol must

12. CONTAINERS FOR STORAGE
MATERIALS:-
1.Bulk storage of liquid is
generally handling by a closed
spherical tanks for preventing
the escape of volatile material
and minimizing contamination.
2.Liquid material are stored in
drum,cans and bottles.

13. STERILE OR ASEPTIC AREA
LAYOUT:-
Sterile medication product are
prepared in a specially designed
and constructed manufacturing
department.
The different operational such
as component preparation,filing
and sterilization are effectively
separated from one another.

14. REFERANCES:-
Cvs Subharamanyam
‘Pharmaceutical production
&management’vallabh
prakashan,first edition
2005,page no-12-29

15. THANK
YOU