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• The Parvoviruses, show a still further degree of dependence .
smallest of all human viruses
• Densovirinae
• Parvovirinae
• Parvovirus
• Dependoviruses
• Erythrovirus
• Bocavirus
Genus Viruses Diseases
Erythrovirus B19 Erythema infectiosum, fetal
infection, Aplastic anemia
Parvovirus RAV-1 Possibly implicated in rheumatoid
arthritis
Bocavirus Newly discovered respiratory and
enteric virus
Dependovirus Adeno-associated(AAV) types 1-5 AAV-2 possibly implicated in fetal
infections
• Erythema infectiosum
• Fetal infection
• Aplastic crisis
• Infectious rash is sometimes known as (fifth disease).
• Slapped cheek syndrome
teratogenic
hydrops fetalis
transfusion of the fetus with
concentrated erythrocytes.
Aplastic crisis(anemia)
• In chronic hemolytic anemia patients (SCA or thalassemia),
parvovirus infection may precipitate an aplastic crisis with very low
Hb and disappearance of circulating reticulocytes
fatal
Parvoviruses
Parvoviruses
Parvoviruses
Parvoviruses
Parvoviruses
Parvoviruses
Parvoviruses
Parvoviruses

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