Partition coefficients are a fascinating and important concept in many fields, from chemistry and environmental science to medicine and pharmacology. They tell us about how a substance will distribute itself between two immiscible phases, like how a drug might move between your blood and tissues, or how a pollutant might spread through soil and water. A partition coefficient, denoted as P or log P, describes the ratio of the concentration of a compound in one phase (usually organic) to its concentration in another phase (often water) at equilibrium. Higher values of P indicate a greater preference for the organic phase, meaning the compound is more lipophilic (fat-loving). Lower values of P suggest a higher affinity for the aqueous phase, implying the compound is more hydrophilic (water-loving).