Parkinson's disease was first recognized in 1817 by James Parkinson. It affects approximately 1 in 500 people in the UK. The main problem with Parkinson's is reduced dopamine in the basal ganglia area of the brain, which controls muscle coordination. Common symptoms include tremors, rigid muscles, slow movement, impaired speech and posture, and loss of manual dexterity. Medication can help replace dopamine and relieve symptoms, but there is no cure currently.