Para amino phenol (PAP) is a widely used intermediate in the pharmaceutical industry, primarily used to manufacture paracetamol. More than 80% of PAP worldwide is used for paracetamol production. China is a major producer and exporter of PAP, with notable producers including Taixing Yangzi, Liaoning Shixing, and Anuhi Bayi Chemical. India is also a major consumer of PAP, importing around 21,000 tons annually from China. PAP is manufactured directly from nitrobenzene and hydrogen in a single-step process using an aqueous acid and catalyst.

1. Para Amino Phenol
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2. Para amino phenol or 4-aminophenol (pAP) is
one of the most widely used intermediate in
the pharmaceutical industry.
Primarily, pAP is used in the manufacture of
paracetamol, a widely used over-the-counter
analgesic (pain reliever) and antipyretic
(fever reducer).
More than 80% of para amino phenol
worldwide is used for manufacturing
paracetamol. The pharmaceutical sector
while 7 % is used as rubber antioxidant and
5% is used in dyes and miscellaneous
purposes.

3. Paracetamol
manufacturing companies
came to be located in
emerging nations of China
and India.

4. China has a lot of manufacturers of PAP and paracetamol
However, the notable ones which
are large and established are the following p-
aminophenol producers:
• Taixing Yangzi – 35000 TPA
• Liaoning Shixing – 40000 TPA
• Anuhi Bayi Chemical – 60000 TPA
• Anqiu Luan Pharma – 10000 TPA
Out of the above producers, only Anuhi Bayi
Chemical uses the nitrobenzene hydrogenation
route. The other producers use PNCB route.

5. India is one of the major users of p-amino
phenol and is the second largest market for
this product after China
• The demand of PAP in India based on paracetamol
capacity that exists is close to 38,500 TPA.
• However, all the PAP and paracetamol capacity is
currently not being utilized.
Easy availability of competitive PAP from China,
pollution and credit terms are the major reasons for
the imports.
• India currently imports close to 21000 TPA of PAP. All
the imports of PAP happen from China.

6. Manufacturing Process:
• Para Amino Phenol is manufactured directly from
Nitrobenzene and Hydrogen in presence of aqueous
Sulphuric acid.
• Single step process for the preparation of p-
aminophenol by hydrogenation of nitrobenzene in
presence of an aqueous acid over a mono or
bimetallic catalyst
• Iron Reduction method - The higher iron content of
Chinese PAP has made China's manufacturers
difficult to find, for the surplus PAP, new overseas
markets except the Asian market, the major
destination of China's exported PAP. All the Chinese
PAP manufacturers except one adopt iron reduction
method.

9. Manufacturing process of Para amino phenol

12. Products&pricesintheMarketPlace

17. The main purpose of Para Amino Phenol
market research report To give detail
qualitative and quantitative analysis on the
business chain scenario, key market players,
market size, upstream raw material details,
product cost, and marketing channels.
Para Amino Phenol the market also provides
current trends, organizations, and
acquisitions, region-wise growth analysis
along with challenges that are concerning the
growth.
Key Players of Global Para Amino
Phenol (PAP) Market

18. Questions?