The document discusses the National Institutes of Health (NIH), which is the primary agency of the United States government responsible for biomedical and public health research. It provides an overview of NIH's structure and budget. Specifically, it notes that NIH is made up of 27 separate institutes and centers and has an annual budget of over $32 billion which is spent on both extramural (over 80% of budget to outside researchers) and intramural (internal NIH campus) research. It also outlines NIH's goal to support fundamental biomedical research and apply new knowledge to improve health outcomes.