Presentation by Prof Chris Rowe, ADNet, to the 'Unlocking value from publicly funded Clinical Research Data' workshop, cohosted by ARDC and CSIRO at ANU on 6 March 2019.

2. Three Initiatives and Two Support Packages

3. ADNeT in a Nutshell
• Clinical Quality Registry (CQR) for newly diagnosed
dementia or “mild cognitive impairment”
• Memory Clinics – expand, standardize and support
• Clinical Trial sites – expand and support
• Longitudinal (n=4,000) and Trial ready (n=500) cohorts –
blood, MRI, cognition, amyloid and tau PET, +/- CSF every 2 years

4. ADNeT Tech
1.Provide IT infrastructure and support for the key ADNeT initiatives
2.Develop and harmonise innovative diagnostic technologies (i.e. PET
and MRI imaging and blood and CSF biomarkers).

5. The Australian Imaging Biomarkers and Lifestyle
Study of Ageing
.
Commenced late 2006

6. 0m 18m 36m 54m 72m 90m 108m 126m
CN 1476 1034 776 684 523 419 376 219
MCI 394 174 107 79 59 34 28 19
AD 427 286 219 127 68 44 30 6
Other 17 7 10 12 8 6 3 2
Total 2314 1501 1112 902 658 503 437 246
Cumulative
Withdrawn 468 681 838 986 1066 1129 1153
% Follow up
complete 81% 68% 61% 49% 40% 37% 21%
AIBL cohort : Number of assessments

7. 3,500 researchers granted access to AIBL data via
www.adni.loni.usc.edu
Includes access granted to 112 companies e.g.:
Abbott Labs, Abiant, ADM diagnostics, Astra Zeneca, Avid, BioClinica, Biogen Idec, Bristol-Myers Squibb, Cogstate Cytokinetics, Eisai, Elan, Eli Lilly, GE Health Care,
General Resonance, Genetech, Imorphics, Iris Biotechnologies, Janssen, Johnson Johnson, M and M Scientific, Merck & Co, Mimvista, Pentara Corp, Pfizer, Philips,
Predixion software, Rancho Biosciences, Servier, Siemens, Soft team solutions, UCB, United Biosource Corp.
AIBL has also received 250 Expressions of Interest for access to more detailed data.
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