oleander PPT for students of FMT

1. Dr.PREETI .R.UDGAVE
KarvIr(Oleander)

2. Identification
Synonyms-
Hayari
Haymar
Ashwamar
Kanir
Chandatak
Kaner
Ashwantk
 English-Oleander,Rose laurel
 Latin name-Nerium odorum (white)
Cerbera thevetia(Yellow)

3.  Family-Apocyanaceae
 Type of poison-Cardic Poison
 Active Principle-
 White-
 Nerin Consisting of 3 glycosides
Neriodorin,Neriodorein &Karabin.
 Yellow-
 Thevetin,Cerberin(in milky juice)
 Thevotoxin(Karnels of seeds)
 Nerifolin & Peruvoside.

4. Mode of Action
 Yellow -Neriodorin Acts Like Digitalis & Can cause
death due to cardiac failure.
 Neriodorein acts as Picrotoxin and can cause
muscular twitching .
 Karabin acts on the heart like digitalis and on the
spinal cord as strychnine.
 White -Thevetin is a Powerful Cardiotoxin .
 Thevotoxin and Nerifolin are less poisonous and acts
like digitalis.
 Cerberine acts like strychnine.
 It acts as a whole Cerebrocardiac poison.

5. fatalality
 White-
 Fatal dose-5 to 15 leaves
15gms of root
 Fatal period -24 to 36 hrs
 Yellow-
 Fatal dose- 8 to 10 seeds
15 to 20mg 0f root
5-15 leaves
 Fatal period-2 to 24 hrs

6. Poisonous Effects
 White Oleander-
 When taken orally-
Peculiar taste in the Mouth
Vomiting ,Abdominal pain Frothy salivation, Restlessness
Slow and Weak Pulse, Hurried respiration, Difficulty in
swallowing ,Lock jaw ,Muscular twitching of extremities like
Tetanic spasm ,Exhaustion ,Drowsiness ,Dilated Pupils,
Coma and Death from Heart Failure
 When Smoke from Burning Plant inhaled-
Cough, Frothy salivation Dysphasia Fibrillary twitching of
muscles slow weak and feeble pulse low BP hurried Stertorus
respiration
 Contact with the plant and its flower may cause contact
dermatitis and respiratory problems

7.  Yellow oleander-
• Burning sensation of Mouth
• tingling of the tongue ,Dryness of the Throat
• Vomiting Diarrhea Headache Faintness Dizziness
• Dilated pupils ,loss of muscle power ,
• Weak feeble Pulse
• Low BP Hurried Stertorus respiration
• Irregular Action of Heart somewhat resembling that to
Digitalis
• Drowsiness Tetanic convulsions
• Coma Collapse
• Death due to Peripheral Circulatory Failure.

8. Treatment
 White-
 Stomach wash with weak KMNO4 or Tannic acid
solution
 Decontamination
 Morphine or Pethidine 5mg IM for Pain
 Correction of Cardiac Arrhythmias with Lidocaine
&Phenytoin
 Control of Vomiting & Diarrhea
 Sedation to Control Spasm
 Correction of Fluids & Electrolytes Disturbances
 Absolute bed rest
 Symptomatic treatment

9.  Yellow -
 Decontamination
 Stomach wash with weak KMNO4 or Tannic acid solution
followed by Animal Charcoal suspended in water
 IV administration of Molar solution of Sodium lactate to
combat Acidosis & 5% glucose solution with 1.2mg of
atropine
 2ml of Adrenaline 1:1000 & 2mg of Nordrenaline to
counteract Heart Block & low B.P
 Choral hydrate ,Potassium bromide ,
 Barbiturate preparation for convulsion
 Stimulants ,Analeptics
 Symptomatic

10.  Mahish dadhi + churnit sita
 Vaman with akanth takrapan
 Vamnottar ghritpan
 Shital jalabhishek,shit upchar
 Mahish dugdh +sambhag sharkara
 Arktwak panyat vatun dene
 Haritaki churn +takra
 Koshn navneet

11. P M Appearance
 White-
• Petechial hemorrhages on the heart are characteristic
feature
 Nerium odorum resist heat &can therefore be detected
even from the burnt remains of the dead body.
 Yellow-
• signs of gastrointestinal irritation
 Congestion of various organs
 Generalized enlargement of veins &Subendocardial
Ecchymosis
 It resist putrefaction & can be detected even years after
death in exhumed putrefied bodies.

12. Medicolegal Aspects
 White-
 Suicidal poison
 Abortifacient
 Accidental –when used as Love Philter
 When used to reduce swelling ( decoction of leaves)
 Root paste for Venereal dise.treatment,Cancerous conditions,
other growths
 Cattle poison
 Yellow-
 Suicidal
 Accidental by quacks
 Used for illegal abortions
 Cattle poison
 Homicidal rare

13. Kalpa
 Karviradyatail
 Karvir yog
 Kasisadi taila
 Sarbakarmika agada
 Karvir is advised to use as lepa in luta visha(AS)

14. THANK YOU