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This is the presentation about "Nutritional Epidemiology". By lacking of different minerals in our food we may suffer different types of disease... The types of disease are mentioned in this presentation.
This is the presentation about "Nutritional Epidemiology". By lacking of different minerals in our food we may suffer different types of disease... The types of disease are mentioned in this presentation.
it contains info about infant and young child feeding guidelines ,breast feeding, complementary feeding, supplementary feeding, feeding in hiv aids, ims act etc
A discourse the ideal feeding practices from pregnancy to infancy with a closer look into malnutrition, breastfeeding, complementary feeding and related interventions.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
2. Nutrition Care Process
1. Nutrition Assessment
2. Nutrition Diagnosis
3. Nutrition Intervention
4. Nutrition Monitoring and Evaluation.
ADA. international Dietetics and Nutrition Terminology Reference Manual; 2011.
2
3. Nutrition Intervention
• is defined as purposefully planned actions
intended to positively change a nutrition-
related behavior, environmental condition, or
aspect of health status for an individual, target
group, or the community at large.
• It consists of two components: planning and
implementation.
ADA. international Dietetics and Nutrition Terminology Reference Manual; 2011.
3
4. NUTRITIONAL
INTERVENTIONS
HEALTH NONHEALTH
INTERGRATED
NURTITIONAL PACKAGE
OTHER
4
5. INTERGRATED NURTITIONAL PACKAGE
• A special nutrition intervention
programme, with inter- sectoral
collaboration, using life cycle
approach.(Currently only in 6
districts )
• The goal & objective of this package
aiming to reduce the prevalence of
low birth weight using the life cycle
approach
Implementation of integrated nutrition package
Circular letter no - 02.85/2010
5
6. Key Strategy- Life cycle approach
Pre-
pregnant
Women
Adolescent Pregnant
Girl Women
Infant &
Young Child Lactating
Pre school Mother
child
6
7. Nutrition Rehabilitation Programme (NRP)
• Is a component of INP
NRP
SAM MAM
Severe Acute Moderate Acute
Malnutrition Malnutrition
Ready to Use Therapeutic Corn Soya Blend or
Food(BP 100/Plumpy UNIMIX
nut) High energy biscuits
7
8. Opportunities
Through
Through Pre- • Home visits
• Home visits pregnant • Clinics
• School MI Women
Adolescent Pregnant
Girl Women
Through
Through • Home visits
• Home visits Infant & • Clinics
• Preschool MI Young Child Lactating
• CWC Pre school Mother
child
8
9. PRE PREGNANCY CARE
• Registration of eligible couples early
• Nutritional status assessment and
management (anaemia & wasting)
• Health screening
(DM,HT,BA,HEART DIS.)
• Folic acid supplementation
(400mcg/day)(?5mg)
• Family planning if necessary
• Rubella immunization 9
10. Care of Pregnant mother
• Early registration
• Domicilliary & clinic based care
• Nutritional assessment (BMI & Hb)
• Monitoring pregnancy weight gain
• Iron, folate, Vit C , calcium lactate
supplimentation
• De-worm treatment after first trimester
• Thiposha /corn soya blend(CSB) suppliments
10
12. Micronutrient supplementation for
pregnant mother
After 12 wks of POA
• Iron/folate – 01 tab
(60 mg elemental iron & 400 mcg folic acid )
• Vit C – 01 tab ( 50/100mg)
• Calcium lactate – 01 tab (300mg)
• One tablet of Mebendazole ( 500 mg )
Single dose
12
13. Care of lactating mother
• Vit A Mega dose
• Educate on diet
Extra servings of starch based foods at each meal
Consume extra piece of fish/egg/dried fish,extra servings of
pulses, vegetables and green leaves daily
• Postpartum visits
Screening for comlications
Nutrition education
Support for breast feeding
• Provision of micronutrients (iron ,Vit C, & Ca)
for lactating mothers – 6/12
• Promote family planning to space pregnancy
13
14. Infant & young children
• Code for breast feeding
• Baby friendly hospital initiative
• Lactation management centers
• Exclusive breast feeding for completion of 6
months & continue up to 2 years
• Complimentary feeding programs
• Growth monitoring & promotion
• Vit A mega dose , Thriposha/CSB, immunization
• ECCD
14
15. Growth monitoring & Promotion
Age group Weighing Measuring length
Birth to 2 years Once a month At 4,9,18,24 months
If any problem once in
two months
2-5 years If growing Once in 3 Every 6 months
well months
If any Once a month Every 3 months
problem
Growth monitoring – consist of measuring, recording and
interpreting an individual’s growth over a period of time
Promotion – providing interventions to maintain and optimize the
growth of normal children and preventing at risk children becoming
malnourished
15
16. Pre school children
• Growth monitoring & promotion
• ECCD
• Thriposha,CSB
• Food demonstrations
16
17. Thriposha Intervention Programme
• Thriposha program was initiated in 1973 by the Ministry of
Health, with the assistance of CARE, to combat the high
incidence of child malnutrition (protein-energy
malnutrition), low birth weight, and micronutrient
deficiencies of iron and vitamin A in key biological groups in
Sri Lanka.
• produces around 1.5 million packets of Thriposha every
month and they are distributed among around 750,000
pregnant women, breast feeding mothers, and underweight
children.
• For the current production amount which is only 60 % of the
requirement, about 10,000 tonnes of maize and 8,000 tonnes
of soya beans are required annually as ingredients.
• Sri Lanka government spends around Rs. 1.25 billion per year
for the production of Thriposha 17
18. Thriposha Intervention Programme
Target group
1. All pregnant (antenatal) mothers throughout their
pregnancy.
2. All lactating (postnatal) mothers for a period of six
months after delivery.
3. Children above 6 months of age to 5 years who are
• Underweight
• Loss of weight for 3 consecutive months
• Hospitalized children who fall into above categories.
18
19. Ingredients present in Thriposha
Ingredients %
Maize 66
Soya 30
Full cream milk powder 3
Vitamin premix o.1
Mineral premix 0.9
Report on Evaluation of Thriposha Food Supplementation
Programme 2008 Submitted by Department of Applied
Nutrition Wayamba University of Sri Lanka 28 August 2008
19
20. Ingredients present in Thriposha
Report on Evaluation of Thriposha Food Supplementation Programme 2008 Submitted by
Department of Applied Nutrition Wayamba University of Sri Lanka 28 August 2008 20
21. Supplementation of Thriposha
Thriposha is a cooked ready to eat supplementary food
50 g = 150 kcal
Age Triposha Sugar Oil/Coconut Kcal
Tbs Tsp /Tbs
Child 6-9 mons 3 With breast 01 Oil Tsp 200
milk
Child 10-12 mons 3 1 Tsp 01 Oil Tbp 250
Child 1-5 yrs 3 1 Tbs 01 Co.nut Tbs 300
Pregnant Women 3 1 Tbs 02 Coconut 350
Tbs
Lactating Mothers 3 1 Tbs 02 Coconut 350
Tbs
Intergrated nurtitional package manual 2010
21
22. Supplements for school children
In Grade 7 & 10, all 01 tab of Mebendazole(500mg)-at the on set
children 01 tab of Ironfolate/Ferrous Sulfate + 01 tab of Vit C
(2009 all children - once a week for 24 weeks
from grade 6 above ) - during school holidays the tablet should be
given to the child with instruction
Children who are 01 tab of Mebendazole(500mg)-at the on set
clinically anaemic 02 tabs of Ironfolate/Ferrous Sulfate + 01 tab of Vit C
- for 1 month or till their Hb% levels normal
After that same treatment for another 2 months to
replenish the iron stores
All children in 1,4,7,10 Vit A mega dose(100 000)
All children in 1,4 01 tab Mebendazole
All children (<200)
22
23. Issues in Thriposha Programme
1. Sharing - the supplement may be consumed by the entire
family rather than the target beneficiary;
2. Substitution - when the supplement is given for the under-
five child, the mother may reduce the child's regular
food, resulting in no increase in nutrient intake;
3. Distortion of growth monitoring - since Thriposha eligibility
is linked to recording of the child as under weight on the
growth card, weights may not be recorded accurately;
4. Dependency - the free distribution of the food may reinforce
a dependent attitude on the part of the recipient;
5. Sustainability - the production of Thriposha is dependent on
supply o f raw materials and imported commodities (Milk
powder) and they are quite expensive.
23
24. School children & adolescents
• School medical inspection
• Immunization
• Ferrous folic acid supplementation
• Growth monitoring
• Dental care
• Hygiene promotion
• School health clubs
• School feeding programmes
(milk,mid-day meal)
• Canteen policy
• School exercise programme
24
28. Vitamin A Megadose Supplementation
Revised Schedule
Vitamin A Megadose Supplementation Revised Schedule
Circular no 01-05/2009
28
29. Corn Soya Blend or UNIMIX
• A supplementary food
• Admission criteria
children aged 6 months – 5 years with Moderate Acute Malnutrition
(MAM)(weight for height/length less between -2SD to -3 SD) in districts
with INP
• If child is having wt/ht less than – 3SD
Therapeutic feeding Programme of the Nutrition Rehabilitation
Programme – Ready to Use Therapeutic Food (BP 100/Plumpy nut)
• Discharge criteria-
1. when child reach above – 1 SD for WT/HT and remain so at two
consecutive Programme distributions
2. Not improved even after 3 months – refer to paediatrician
29
30. Corn Soya Blend or UNIMIX
how to use
• Mix with some drinking water to make a paste
• Bring the boil for 10 minutes ( no more – no less) and serve
UNIMIX/CSB 3 full tablespoons
Water 1 cup
Sugar 1 table spoon ( after 9/12)
Oil /margarine/butter or 1 table spoon
Coconut 3 tablespoons
50 g daily provide 150-190 kcal/day
1500g per month per child
30
31. Issues in CSB Programme
• Not focused on targeting
group (not using the
admission criteria properly)
• Not adhere to the discharge
criteria
• Problems in growth
monitoring – because use of
WT/HT instead of WT/AGE
31
32. Multiple Micronutrients (Sprinkles)
• Home based fortification
• Target
All infants & young children between 6 to 24 months
• Exclude
Children completing 24 months to be excluded
• Dose
15 sachets to be consumed within 30 days(EOD/DAILY)
• Duration
For a period of 4 consecutive months (120days) for each
child from the date of commencement
32
33. Multiple Micronutrients (Sprinkles)
(Nutritional Anemia Formulation)
Micronutrient Amount
Iron 12.5 mg
Zinc 5 mg Zn & Iron deficiency
generally co -exist
Folic Acid 160 µg
Vitamin A 300 µg RE Children continue to get
Vit A mega dose
Vitamin C 30 mg Enhance iron absorption
33
34. Multiple Micronutrients - Administration
• Whole sachet should be added to half a cup of semi
solid or solid food – one per day
• Mixed well and fed to the child within 30 min
because the vitamins and minerals in the Sprinkles
will cause the food to noticeably darken.
• Should be never mixed with water or any other fluids
as it is not water soluble
34
35. Issues in Multiple Micronutrients (Sprinkles)
• Poor compliance
• Poor knowledge on method of use
• Discouraged by hospital setup
35