The document discusses conditions for effectively deriving a Q-Matrix from assessment data using Non-Negative Matrix Factorization (NMF). It describes a study that used NMF to interpret a Q-Matrix and derive the underlying skills assessed by test questions in mathematics, biology, history and French. The study analyzed response data from 297 respondents to a 40 question test. NMF was able to effectively cluster test questions that assessed well delineated skills.