Not all but most important and most common tumors are covered along with DICOM images and reference taken from standard book only

1. NON GLIAL
TUMOR
BY DR AVINASH
DAHATRE
JR RADIOLOGY DEPT.

2. MIXED GLIAL NEURONAL AND
NEURONAL TUMOR
Glial neuronal tumor is a mixture of abnormal ganglion cell
and glial stroma.
Most common is ganglioma

3. GANGLIOMA
It is the unusual tumor containing neuronal and glial elements.
It is a small firm, neuronal mass.
E.g, Desmophyte cystic ganglioma is most common type in infants as they are large
cystic frontal lobe tumor.
AGE:- occurs in children of <30yrs.
Most symptomatic in second decade of life.
Seizure is most common symptom followed by increased intracranial pressure.
Tumor is slow growing and present for yrs.

4. T2WI
FLAIR T2

5. LOCATION:- can be anywhere but supratentorial most common, also seen in
temporal lobe
IMAGING:-
CT:- iso to Hypodense mural nodule often calcified.
MR imaging :- Hypointense in T1WI and Hyperintense on T2WI

6. COR T1 shows
hypointense supraoptic
lesion.
COR T1 + C
AXIAL T2 image showing
hyperintense lesion.

7. GANGLIOCYTOMA
Purely neuronal tumor.
Lacks Glial cells.
Shows clear evidence of brain malformation and dysplasia.

8. LHERMITTE’S DUCLOS
DISEASE
A/k/as dysplastic cerebellar ganglioma.
Characterized by folia hypertrophy.

9. There is
abnormal
population of
large neurons in
granular layer.
Myelination of
molecular layer.
CORTEX IS
THICKENED.

10. AXIAL ADC
AXIAL T2

11. DYSMORPHIC
NEUROEPITHELIAL TUMOR
(DNET)
Benign lesion.
Most commonly found in temporal lobe.
Shows 3 characterstic:-
i. Specific ganglioneuronal element
ii. Nodular component
iii. Cortical dysplasia

12. T1 Post contrast
T2WI AXIAL FLAIR AXIAL DWI AXIAL

13. CENTRAL NEUROCYTOMA
They are well defined sharply circumscribed lobulated intraventricular
mass adjacent to foramina of monro and septum pellucidum.
Necrosis and cyst formation is common.
Extensively vascularized which can lead to intraventricular
hemorrhage.
AGE OF ONSET:- Reported in 30yrs of age.
SYMPTOMS:- Headache and increase intracranial pressure.

14. LOCATION:- Most common site is lateral ventricle.
AXIAL T1WI POST CONTRAST AXIAL T1WI

15. appears isodense to
the cortical grey matter,
containing foci of
calcification as well as
cystic areas with
heterogeneous
enhancement on
postcontrast images

16. MENINGEAL AND
MESENCHYMAL TUMOR
MENINGIOMA
HEMANGIOBLASTOMA

17. MENINGIOMA:-
Most common non glial primary CNS tumor.
Most meningioma arise from meningothelial cell in
arachnoid granulation.
Few arise from dural fibroblastand others from
arachnoid.
NFII is major genetic factor.(Chr.22)
Meningioma also a/w sex hormones (estrogen,
progesterone,androgen)
Dural attachment can be like pedunculated, stalk like.

18. MENINGIOMA
TYPICAL
95% Benign
ATYPICAL
5-7%
ANAPLASTIC
1-2%Malignant
WHO CLASSIFICATION:-

19. MENINGIOMA:-
CHARACTERSTIC:-
Age :- 40-60yrs rare in children.
Male: female :- 2:1 to 4:1
Location:- 90% supratentorial and occurs where arachnoid granulation is present.
Meningiomas are sharply circumscribed, well delineated tumor which are
bossellated or lobulated.
Often necrotic or hemorrhagic.
Cystic and xanthomatous changes occurs.
Collar of thickened dura surround the base.

21. Plain anteroposterior radiograph,
performed in the patient seen in the
previous slide, demonstrates left frontal
lucency
CT image showing sharply
circumscribed round
hyperdense mass

22. T1-weighted MRI scan with contrast
shows a pineal region meningioma.
Axial, T1-weighted MRI scan (right)
reveals a homogenously enhancing,
dural-based lesion, the classic
appearance of a meningioma.
MRI:- >95% shows heterogenous enhancement & 60% have collar of
thickened enhancing tissue that surround dural attachment called
‘DURAL TAIL’.

23. MENINGIOMA MIMIC’S
SCHWANNOMA
GLIOMA
METASTASIS

24. HEMANGIOPERICYTOMA
They arise from contractile cell surrounding the cappilaries hence called as
angioblastic meningioma.
Age of onset:- 42yr
On CT:- appears heterogenous in pre and post contrast study.
Low density cystic necrotic area.
MRI:- On T1WI- Isointense to cortex
T2WI – Heterogenous
On PD – slight hyperintense

25. Fig.SAG T1-weighted MRI scan shows a
hemangiopericytoma that mimics an olfactory groove
meningioma.

26. HEMANGIOBLASTOMA
Vascular neoplasm associated with VHL (von hippel landau).
Arise from primitive vascular mesenchyme and hematopoetic stem
cell.
Approximate 7% are posterior fossa tumor.
Adult tumor, rare in children.
Location:- 80-85% cerebellum
3-13% Spinal cord
2-3% Medulla

27. Fig. AXIAL CECT
showing Cystic
lesion with non
enhancing walls
and vividly
enhancing mural
nodule in
cerebellum

28. AXIAL T2WI image showing
hyperintense lesion in right cerebellum
T1WI image with contrast demonstrate partially cystic
and enhancing solid mass in the inferior cerebellum with
associated mass effect.

29. PINEAL REGION
TUMOR
GERM CELL
NEOPLASM
GERMINOMA
10- 30yrs age
TERATOMA
2nd decade
CHORIOCARCINOMA
First decade
PINEAL CELL
NEOPLASM
PINEOCYTOMA
Benign
PINEOBLASTOMA
Malignant

30. MEDULLOBLASTOMA
Infratentorial PNET termed as medulloblastoma.
75 % are spherical midline posterior fossa mass.
25% lateral cerebellum
More common in children than in adult.
Age of onset:- < 15 yrs of age.

31. Fig. 1. Noncontrast CT head (A) demonstrates a mildly hyperattenuating focus (red
arrow) in the region of right cerebellar hemisphere. The lesion demonstrates
homogenous enhancement (blue arrow) seen on the contrast-enhanced CT (B). In
addition, mass effect of the right cerebellar hemisphere and brainstem, along with
near complete effacement of the fourth ventricle results in obstructive
hydrocephalus

32. METASTATIC
MEDULLOBLASTOMA
They disseminate at extra cranial site – primarily bone.
Typically lytic or osteoblastic lesion.
CECT shows linear enhancing disseminated foci.

33. PRIMARY CEREBRAL
NEUROBLASTOMA
They are supratentorial neuroblastoma.
Large bulky hemispheric mass with necrosis and cyst
formation.
Prominent vessel seen.
Age of onset:- <5yrs of age.
Location :- anywhere,
Most common site is frontal, parietal and next to
lateral ventricle.

34. SAG T1WI- Image demonstrate a large
mass centered deep in the left hemisphere
with prominent necrotic/cystic areas
centrally and diffusion restriction

35. REFRENCE:-
ANNE G OSBORN BOOK OF RADIOLOGY