Noma (necrotizing ulcerative stomatitis) is a rapidly spreading gangrenous infection that commonly affects malnourished or immunocompromised individuals. It is usually a secondary complication caused by conditions like measles, tuberculosis, or HIV/AIDS. Predisposing factors include unsafe drinking water and proximity to livestock. The infection begins near the mouth and causes soft tissue necrosis and a foul odor. It can spread to involve the palate, tongue, and sometimes genitals. Treatment aims to control the infection with antibiotics and improve the patient's nutritional status. The World Health Organization and International No NOMA Federation have worked to increase awareness and reduce the global prevalence of this devastating disease.