The document discusses the impact of nanotechnology on cosmetics, highlighting over 125 products utilizing nanomaterials as of September 2008. It addresses the potential risks and regulatory challenges posed by nano-sized materials, which may alter exposure risks and cross the boundary between cosmetics and drugs. Action points include the need for clear criteria for defining nanomaterials and enhanced transparency and knowledge-sharing in the industry.

1. Nanotechnology and
Cosmetics
FDA Nanotechnology Public Meeting
September 08 2008
Rockville, MD
Andrew D. Maynard
Chief Science Advisor, Project on Emerging nanotechnologies
Woodrow Wilson International Center for Scholars

2. Over 800 products
(Sept 2008)
125 cosmetics products
(Sept 2008)
62 added since October
2006
Applications range from
anti-ageing creams to
hair styling products
www.nanotechproject.org/consumer

3. A
n
t
i
A
g
i
n
g
C
l
e
a
n
s
e
r
C
o
m
p
l
e
x
i
o
n
C
o
n
d
i
t
i
o
n
i
n
g
C
o
s
m
e
t
i
c
D
i
s
i
n
f
e
c
t
a
n
t
B
r
e
a
s
t
E
n
l
a
r
g
e
m
e
n
t
E
x
f
o
l
i
a
t
i
o
n
H
a
i
r
S
t
y
l
i
n
g
M
o
i
s
t
u
r
i
z
e
r
P
e
r
f
u
m
e
P
l
u
m
p
e
r
W
h
i
t
e
n
i
n
g
M
u
l
t
i
p
l
e
U
n
s
p
e
c
i
f
i
e
d
Breasts
Cuticles
Eyes
Face
Skin
Hair
Hands
Lips
Neck
Multiple
Unspecified
20
0
10
A
r
e
a
o
f
A
p
p
l
i
c
a
t
i
o
n
Use
Number
Current State of Knowledge on Nano-Cosmetics
Product Functions & Application Areas
Source: PEN Consumer Products Inventory, September 2008. www.nanotechprojects.org/consumer

4. 0
10
20
30
40
50
Nano
Capsules
Metal
Metal
Oxide
Organic
Carbon
Mineral
Other
Number
of
Products
Current State of Knowledge on Nano-Cosmetics
Nanomaterial Category
Source: PEN Consumer Products Inventory, September 2008. www.nanotechprojects.org/consumer

5. 0
5
10
15
20
25
30
35
40 Silver
Fullerene
Gold
Silica
ZnO
Mica
Titanium
Collagen
Copper
Platinum
Alumina
Carbon
TiO2
Unspecified
Unclear
Mixture
Number
of
Products
Current State of Knowledge on Nano-Cosmetics
Principle Nanomaterials Used
Source: PEN Consumer Products Inventory, September 2008. www.nanotechprojects.org/consumer

6. Nano-Challenges
• Nano-sizing materials may change their risk
profile
– Exposure and dose may be influenced by particle
size, shape, and surface properties

7. www.nanotechproject.org/inventories/consumer/browse/products/6825/

8. Nano-Challenges
• Nano-sizing materials may change their risk
profile
– Exposure and dose may be influenced by particle
size, shape, and surface properties
– Hazard may depend on scale-associated properties
in addition to chemical identity

9. www.nanotechproject.org/inventories/consumer/browse/products/nano_gold_energizing_cream/

10. Nano-Challenges
• Nano-sizing materials may change their risk
profile
– Exposure and dose may be influenced by particle
size, shape, and surface properties
– Hazard may depend on scale-associated properties
in addition to chemical identity
• Nanotechnology has the potential to blur the
boundary between cosmetics and drugs

11. www.nanotechproject.org/inventories/consumer/browse/products/5204/

12. Action Points
• Criteria are needed for defining new materials
for legal or regulatory purposes
• Relevant regulatory trigger-points are needed
• Nanomaterial-specific knowledge is needed
– Through targeted research
– Through information-sharing by industry
• Transparency is essential