The document discusses gene mutations and their effects. It defines a mutation as a change in genetic material that can affect chromosomes or genes. Mutations can occur during DNA replication from errors or environmental exposures. There are two main types of mutations - point mutations, which change a single nucleotide, and frameshift mutations, which insert or delete nucleotides, altering the coding. The document provides examples of different mutation types, like missense mutations changing amino acid sequences and nonsense mutations introducing stop codons. It includes an assessment with multiple choice questions testing understanding of mutation concepts.

1. ARAULLO HIGH SCHOOL
Teacher
Mr. Dwight Fernandez
SCIENCE 10
GENE MUTATIONS
Explain how mutations may cause changes in the
structure and function ofa protein (S10LT-IIId-37)

3. OBJECTIVES
analyze the changes that can occur in a
DNA sequence and its corresponding
effects.
differentiate the types of gene
mutations.
value how variation is part of our
uniqueness as human organisms.
At the end of the lesson, the students should
be able to:

6. is a change in genetic
material. It may affect
sets of chromosomes,
entire chromosomes, or
genes
MUTATION

7. It can occur during DNA replication if errors are made and not corrected in
time. Mutations can also occur as a result of exposure to environmental
factors such as smoking, sunlight, and radiation. Often cells can recognize
any potentially mutation-causing damage and repair it before it becomes a
fixed mutation.
MUTATION

8. POINT MUTATION
FRAMESHIFT MUTATION

9. THE BOY CUT HIS LIP AND ATE THE HOT DOG

10. THE BOY CUT HIS LIP AND ATE THE HOT DOG
MISSENSE SUBSTITUTION
THE BOY CUT HIS FIP AND ATE THE HOT DOG

11. It occurs when a mutation changes
the sequence of amino acids.
MISSENSE SUBSTITUTION

12. THE BOY CUT HIS LIP AND ATE THE HOT DOG
NONSENSE SUBSTITUTION
THE BOY CUT HIS

13. It occurs when a mutation changes an amino acid to
a stop codon. The Ribosomes stop translating and
proteins are not fully made.
NONSENSE SUBSTITUTION

14. THE BOY CUT HIS LIP AND ATE THE HOT DOG
SILENT SUBSTITUTION
THE BOY CUT HIS LIP AND ATE THE HOT DOG

15. It occurs when a mutation changes the nucleotide
sequence. However, it still produces the same kind of
protein or amino acid.
SILENT SUBSTITUTION

17. THE BOY CUT HIS LIP AND ATE THE HOT DOG
FRAMESHIFT BY INSERTION
THE BOY CUT HIS LIS PAN DAT ETH EHO TDO G

18. THE BOY CUT HIS LIP AND ATE THE HOT DOG
FRAMESHIFT BY DELETION
THE BOY CTH ISL IPA NDA TET HEH OTD OG

19. It occurs when one or more nucleotides are either
removed or inserted which completely changes the
sequence of codons.
FRAMESHIFT MUTATION

20. MUTATIONS ORGANIZER

22. ASSESSMENT

23. Point Mutation
Frameshift Mutation
Single Base-Pair Substitution Mutation
Both A and C
A type of mutation wherein one nucleotide is changed to a different
nucleotide.
1.
2.
3.
4.
MULTIPLE CHOICE

24. Frameshift Deletion Mutation
Substitution Nonsense Mutation
Substitution Missense Mutation
Substitution Silent Mutation
It occurs when a mutation changes the sequence of amino acids.
1.
2.
3.
4.
MULTIPLE CHOICE

25. Frameshift Deletion Mutation
Substitution Nonsense Mutation
Substitution Missense Mutation
Substitution Silent Mutation
Dave observed that one nucleotide was changed in the Mutated DNA.
However, the same amino acid was produced what mutation is this?
1.
2.
3.
4.
MULTIPLE CHOICE

26. Frameshift Deletion Mutation
Substitution Nonsense Mutation
Substitution Missense Mutation
Substitution Silent Mutation
It occurs when a mutation changes an amino acid to a stop
codon. The Ribosomes stop translating and proteins are not fully
made.
1.
2.
3.
4.
MULTIPLE CHOICE

27. Point Mutation
Frameshift Mutation
Single Substitution Mutation
Both A and C
This mutation occurs when one or more nucleotides are either removed
or inserted which completely changes the sequence of codons.
1.
2.
3.
4.
MULTIPLE CHOICE

28. Point Mutation
Frameshift Mutation
Single Base-Pair Substitution Mutation
Both A and C
A type of mutation wherein one nucleotide is changed to a different
nucleotide.
1.
2.
3.
4.
MULTIPLE CHOICE

29. Frameshift Deletion Mutation
Substitution Nonsense Mutation
Substitution Missense Mutation
Substitution Silent Mutation
It occurs when a mutation changes the sequence of amino acids.
1.
2.
3.
4.
MULTIPLE CHOICE

30. Frameshift Deletion Mutation
Substitution Nonsense Mutation
Substitution Missense Mutation
Substitution Silent Mutation
Dave observed that one nucleotide was changed in the Mutated DNA.
However, the same amino acid was produced what mutation is this?
1.
2.
3.
4.
MULTIPLE CHOICE

31. Frameshift Deletion Mutation
Substitution Nonsense Mutation
Substitution Missense Mutation
Substitution Silent Mutation
It occurs when a mutation changes an amino acid to a stop
codon. The Ribosomes stop translating and proteins are not fully
made.
1.
2.
3.
4.
MULTIPLE CHOICE

32. Point Mutation
Frameshift Mutation
Single Substitution Mutation
Both A and C
This mutation occurs when one or more nucleotides are either removed
or inserted which completely changes the sequence of codons.
1.
2.
3.
4.
MULTIPLE CHOICE

34. ARAULLO HIGH SCHOOL
Teacher
Mr. Dwight Fernandez
SCIENCE 10
GENE MUTATIONS
Explain how mutations may cause changes in the
structure and function ofa protein
(S10LT-IIId-37)