The document describes various DNA, mRNA, and amino acid sequences and mutations between original and mutated sequences. It provides 5 examples of point mutations or frameshift mutations and asks to identify the type of each. It also provides 6 diagrams of chromosomal mutations and asks to identify the type of each chromosomal mutation shown. The mutations identified include missense, nonsense, silent, deletion, insertion, inversion, duplication, translocation.

2. Original DNA Sequence: TAC ACC TTG GCG ACG ACT
mRNA Sequence : AUG UGG AAC CGC UGC UGA
Amino Acid : MET – TRP - ASN - ARG - CYS - STOP
Mutated DNA Sequence: TACATCTTGGCGACGACT
mRNA Sequence :
Amino Acid :
Type of Mutation:
COMPLETE THE BASES BELOW. CLASSIFY EACH AS (FRAMESHIFT)DELETION,
INSERTION OR (POINT MUTATION) MISSENSE, SILENT NONSENSE.

3. Original DNA Sequence: TAC ACC TTG GCG ACG ACT
mRNA Sequence : AUG UGG AAC CGC UGC UGA
Amino Acid : MET – TRP - ASN - ARG - CYS - STOP
Mutated DNA Sequence: TACGACCTTGGCGACGACT
mRNA Sequence :
Amino Acid :
1.
Type of Mutation:
COMPLETE THE BASES BELOW. CLASSIFY EACH AS (FRAMESHIFT)DELETION,
INSERTION OR (POINT MUTATION) MISSENSE, SILENT NONSENSE.

4. Original DNA Sequence: TAC ACC TTG GCG ACG ACT
mRNA Sequence : AUG UGG AAC CGC UGC UGA
Amino Acid : MET – TRP - ASN - ARG - CYS - STOP
Type of Mutation:
COMPLETE THE BASES BELOW. CLASSIFY EACH AS (FRAMESHIFT)DELETION,
INSERTION OR (POINT MUTATION) MISSENSE, SILENT NONSENSE.

5. COMPLETE THE BASES BELOW. CLASSIFY EACH AS (FRAMESHIFT)DELETION,
INSERTION OR (POINT MUTATION) MISSENSE, SILENT NONSENSE.
Original DNA Sequence: TAC ACC TTG GCG ACG ACT
mRNA Sequence : AUG UGG AAC CGC UGC UGA
Amino Acid : MET – TRP - ASN - ARG - CYS - STOP
Mutated DNA Sequence: TACACCTTAGCGACGACT
mRNA Sequence :
Amino Acid :
2.
Type of Mutation:

6. COMPLETE THE BASES BELOW. CLASSIFY EACH AS (FRAMESHIFT)DELETION,
INSERTION OR (POINT MUTATION) MISSENSE, SILENT NONSENSE.
Original DNA Sequence: TAC ACC TTG GCG ACG ACT
mRNA Sequence : AUG UGG AAC CGC UGC UGA
Amino Acid : MET – TRP - ASN - ARG - CYS - STOP
Mutated DNA Sequence: TACACCTTGGCGACTACT
mRNA Sequence :
Amino Acid :
3.
Type of Mutation:

7. COMPLETE THE BASES BELOW. CLASSIFY EACH AS (FRAMESHIFT)DELETION,
INSERTION OR (POINT MUTATION) MISSENSE, SILENT NONSENSE.
Original DNA Sequence: TAC ACC TTG GCG ACG ACT
mRNA Sequence : AUG UGG AAC CGC UGC UGA
Amino Acid : MET – TRP - ASN - ARG - CYS - STOP
Mutated DNA Sequence: TACACCTTGGCGACACT
mRNA Sequence :
Amino Acid :
4.
Type of Mutation:

8. COMPLETE THE BASES BELOW. CLASSIFY EACH AS (FRAMESHIFT)DELETION,
INSERTION OR (POINT MUTATION) MISSENSE, SILENT NONSENSE.
Original DNA Sequence: TAC ACC TTG GCG ACG ACT
mRNA Sequence : AUG UGG AAC CGC UGC UGA
Amino Acid : MET – TRP - ASN - ARG - CYS - STOP
Mutated DNA Sequence: AACACCTTGGCGACGACT
mRNA Sequence :
Amino Acid :
5.
Type of Mutation:

9. EACH DIAGRAM SHOWS A POSSIBLE MUTATIONS OF CHROMOSOMES. USE THE
DIAGRAM TO IDENTIFY THE TYPE OF CHROMOSOMAL MUTATION.
DELETION, INVERSION, DUPLICATION, TRANSLOCATION, INSERTION.
1.
2.

10. EACH DIAGRAM SHOWS A POSSIBLE MUTATIONS OF CHROMOSOMES. USE THE
DIAGRAM TO IDENTIFY THE TYPE OF CHROMOSOMAL MUTATION.
DELETION, INVERSION, DUPLICATION, TRANSLOCATION, INSERTION.
3.
4.
ABC
GH
DEF
IJKL
ABC IJKL
GH DEF

11. EACH DIAGRAM SHOWS A POSSIBLE MUTATIONS OF CHROMOSOMES. USE THE
DIAGRAM TO IDENTIFY THE TYPE OF CHROMOSOMAL MUTATION.
DELETION, INVERSION, DUPLICATION, TRANSLOCATION, INSERTION.
5.
6.
ABC DEF ABC DEFCG

13. Original DNA Sequence: TAC ACC TTG GCG ACG ACT
mRNA Sequence : AUG UGG AAC CGC UGC UGA
Amino Acid : MET – TRP - ASN - ARG - CYS - STOP
Mutated DNA Sequence: TAC GAC CTT GGC GAC GAC T
mRNA Sequence : AUG CUG GAA CCG CUG CUG A
Amino Acid : MET – LEU – GLU – PRO – LEU – LEU
1.
Type of Mutation:
COMPLETE THE BASES BELOW. CLASSIFY EACH AS (FRAMESHIFT)DELETION,
INSERTION OR (POINT MUTATION) MISSENSE, SILENT NONSENSE.
FRAMESHIFT : INSERTION

14. COMPLETE THE BASES BELOW. CLASSIFY EACH AS (FRAMESHIFT)DELETION,
INSERTION OR (POINT MUTATION) MISSENSE, SILENT NONSENSE.
Original DNA Sequence: TAC ACC TTG GCG ACG ACT
mRNA Sequence : AUG UGG AAC CGC UGC UGA
Amino Acid : MET – TRP - ASN - ARG - CYS - STOP
Mutated DNA Sequence: TAC ACC TTA GCG ACG ACT
mRNA Sequence : AUG UGG AAU CGC UGC UGA
Amino Acid : MET – TRP – ASN – ARG – CYS – STOP
2.
Type of Mutation: POINT MUTATION : SILENT

15. COMPLETE THE BASES BELOW. CLASSIFY EACH AS (FRAMESHIFT)DELETION,
INSERTION OR (POINT MUTATION) MISSENSE, SILENT NONSENSE.
Original DNA Sequence: TAC ACC TTG GCG ACG ACT
mRNA Sequence : AUG UGG AAC CGC UGC UGA
Amino Acid : MET – TRP - ASN - ARG - CYS - STOP
Mutated DNA Sequence: TAC ACC TTG GCG ACT ACT
mRNA Sequence : AUG UGG AAC CGC UGA UGA
Amino Acid : MET – TRP – ASN – ARG - STOP
3.
Type of Mutation: POINT MUTATION : NONSENSE

16. COMPLETE THE BASES BELOW. CLASSIFY EACH AS (FRAMESHIFT)DELETION,
INSERTION OR (POINT MUTATION) MISSENSE, SILENT NONSENSE.
Original DNA Sequence: TAC ACC TTG GCG ACG ACT
mRNA Sequence : AUG UGG AAC CGC UGC UGA
Amino Acid : MET – TRP - ASN - ARG - CYS - STOP
Mutated DNA Sequence; TAC ACC TTG GCG ACA CT
mRNA Sequence : AUG UGG AAC CGC UGC GA
Amino Acid : MET – TRP - ASN - ARG - CYS
4.
Type of Mutation: FRAMESHIFT : DELETION

17. COMPLETE THE BASES BELOW. CLASSIFY EACH AS (FRAMESHIFT)DELETION,
INSERTION OR (POINT MUTATION) MISSENSE, SILENT NONSENSE.
Original DNA Sequence: TAC ACC TTG GCG ACG ACT
mRNA Sequence : AUG UGG AAC CGC UGC UGA
Amino Acid : MET – TRP - ASN - ARG - CYS - STOP
Mutated DNA Sequence: AAC ACC TTG GCG ACG ACT
mRNA Sequence : UUG UGG AAC CGC UGC UGA
Amino Acid : LEU – TRP - ASN - ARG - CYS - STOP
5.
Type of Mutation: POINT MUTATION : MISSENSE

18. EACH DIAGRAM SHOWS A POSSIBLE MUTATIONS OF CHROMOSOMES. USE THE
DIAGRAM TO IDENTIFY THE TYPE OF CHROMOSOMAL MUTATION.
DELETION, INVERSION, DUPLICATION, TRANSLOCATION, INSERTION.
1.
2.
INVERSION
DELETION

19. EACH DIAGRAM SHOWS A POSSIBLE MUTATIONS OF CHROMOSOMES. USE THE
DIAGRAM TO IDENTIFY THE TYPE OF CHROMOSOMAL MUTATION.
DELETION, INVERSION, DUPLICATION, TRANSLOCATION, INSERTION.
3.
4.
ABC
GH
DEF
IJKL
ABC IJKL
GH DEF
TRANSLOCATION
DUPLICATION

20. EACH DIAGRAM SHOWS A POSSIBLE MUTATIONS OF CHROMOSOMES. USE THE
DIAGRAM TO IDENTIFY THE TYPE OF CHROMOSOMAL MUTATION.
DELETION, INVERSION, DUPLICATION, TRANSLOCATION, INSERTION.
5.
6.
ABC DEF ABC DEFCG
INSERTION
TRANSLOCATION