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Musculature in
vertebrates
Presented by:-
Bhupen chandra koch
Roll no- 23
M.Sc 3rd
samester
Dept. of zoology
Gauhati university
The Muscular System
• Muscles are responsible for all movement
of the body
• There are three basic types of muscle
– Skeletal
– Cardiac
– Smooth
3 Types of Muscles
Three types of muscle
Skeletal Cardiac Smooth
Classification of Muscle
Skeletal-
found in limbs
Cardiac-
found in heart
Smooth-
Found in
viscera
Striated, multi-
nucleated
Striated, 1
nucleus
Not striated, 1
nucleus
voluntary involuntary involuntary
Characteristics of Muscle
• Skeletal and smooth muscle are elongated
• Muscle cell = muscle fiber
• Contraction of a muscle is due to movement
of microfilaments (protein fibers)
• All muscles share some terminology
– Prefixes myo and mys refer to muscle
– Prefix sarco refers to flesh
Shapes of Muscles
• Triangular- shoulder, neck
• Spindle- arms, legs
• Flat- diaphragm, forehead
• Circular- mouth, anus
Skeletal Muscle
• Most are attached by tendons to bones
• Cells have more than one nucleus
(multinucleated)
• Striated- have stripes, banding
• Voluntary- subject to conscious control
• Tendons are mostly made of collagen fibers
• Found in the limbs
• Produce movement, maintain posture,
generate heat, stabilize joints
Structure of skeletal muscle
• Each cell (fibre) is long and cylindrical
• Muscle fibres are multi-nucleated
• Typically 50-60mm in diameter, and up
to 10cm long
• The contractile elements of
skeletal muscle cells are
myofibrils
Skeletal muscle - Summary
• Voluntary movement
of skeletal parts
• Spans joints and
attached to skeleton
• Multi-nucleated,
striated, cylindrical
fibres
Smooth Muscle
• No striations
• Spindle shaped
• Single nucleus
• Involuntary- no conscious control
• Found mainly in the walls of hollow organs
Smooth muscle
• Lines walls of viscera
• Found in longitudinal or
circular arrangement
• Alternate contraction of
circular & longitudinal
muscle in the intestine
leads to peristalsis
Structure of smooth muscle
• Spindle shaped uni-nucleated cells
• Striations not observed
• Actin and myosin filaments are present(
protein fibers)
Smooth muscle - Summary
• Found in walls of
hollow internal
organs
• Involuntary
movement of
internal organs
• Elongated, spindle
shaped fibre with
single nucleus
Cardiac Muscle
• Striations
• Branching cells
• Involuntary
• Found only in the heart
• Usually has a single nucleus, but can have
more than one
Cardiac muscle
• Main muscle of heart
• Pumping mass of heart
• Critical in humans
• Heart muscle cells
behave as one unit
• Heart always contracts
to it’s full extent
Structure of cardiac muscle
• Cardiac muscle cells (fibres) are
short, branched and
interconnected
• Cells are striated & usually have 1
nucleus
• Adjacent cardiac cells are joined
via electrical synapses (gap
junctions)
• These gap junctions appear as
dark lines and are called
Cardiac muscle - Summary
• Found in the heart
• Involuntary rhythmic
contraction
• Branched, striated
fibre with single
nucleus and
intercalated discs
Muscle Control
Type of
muscle
Nervous
control
Type of
control
Example
SkeletalSkeletal Controlled
by CNS
Voluntary Lifting a
glass
Cardiac Regulated
by ANS
Involuntary Heart
beating
Smooth Controlled
by ANS
Involuntary Peristalsis
Types of Responses
• Twitch-
– A single brief contraction
– Not a normal muscle function
• Tetanus
– One contraction immediately followed by
another
– Muscle never completely returns to a relaxed
state
– Effects are compounded
Where Does the Energy Come
From?
• Energy is stored in the muscles in the form
of ATP
• ATP comes from the breakdown of glucose
during Cellular Respiration
• This all happens in the Mitochondria of the
cell
• When a muscle is fatigued (tired) it is
unable to contract because of lack of
Oxygen
How are Muscles Attached to
Bone?
• Origin-attachment to a movable bone
• Insertion- attachment to an immovable
bone
• Muscles are always attached to at least 2
points
• Movement is attained due to a muscle
moving an attached bone
Structure of Skeletal Muscle:
Microstructure
• Sarcolemma
– Muscle cell membrane
• Myofibrils
– Threadlike strands within muscle fibers
– Actin (thin filament)
• Troponin
• Tropomyosin
– Myosin (thick filament)
Structure of Skeletal Muscle:
The Sarcomere
• Further divisions of myofibrils
– Z-line
– A-band
– I-band
• Within the sarcoplasm
– Sarcoplasmic reticulum
• Storage sites for calcium
– Transverse tubules
– Terminal cisternae
Sliding Filament Theory
• Rest – uncharged ATP cross-bridge complex
• Excitation-coupling – charged ATP cross-
bridge complex, “turned on”
• Contraction – actomyosin – ATP > ADP & Pi
+ energy
• Recharging – reload cross-bridge with ATP
• Relaxation – cross-bridges “turned off”
The Sliding Filament Model of
Muscle Contraction
THANK YOU

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Musculature in vertebrates

  • 1. Musculature in vertebrates Presented by:- Bhupen chandra koch Roll no- 23 M.Sc 3rd samester Dept. of zoology Gauhati university
  • 2. The Muscular System • Muscles are responsible for all movement of the body • There are three basic types of muscle – Skeletal – Cardiac – Smooth
  • 3. 3 Types of Muscles
  • 4. Three types of muscle Skeletal Cardiac Smooth
  • 5. Classification of Muscle Skeletal- found in limbs Cardiac- found in heart Smooth- Found in viscera Striated, multi- nucleated Striated, 1 nucleus Not striated, 1 nucleus voluntary involuntary involuntary
  • 6. Characteristics of Muscle • Skeletal and smooth muscle are elongated • Muscle cell = muscle fiber • Contraction of a muscle is due to movement of microfilaments (protein fibers) • All muscles share some terminology – Prefixes myo and mys refer to muscle – Prefix sarco refers to flesh
  • 7. Shapes of Muscles • Triangular- shoulder, neck • Spindle- arms, legs • Flat- diaphragm, forehead • Circular- mouth, anus
  • 8. Skeletal Muscle • Most are attached by tendons to bones • Cells have more than one nucleus (multinucleated) • Striated- have stripes, banding • Voluntary- subject to conscious control • Tendons are mostly made of collagen fibers • Found in the limbs • Produce movement, maintain posture, generate heat, stabilize joints
  • 9. Structure of skeletal muscle • Each cell (fibre) is long and cylindrical • Muscle fibres are multi-nucleated • Typically 50-60mm in diameter, and up to 10cm long • The contractile elements of skeletal muscle cells are myofibrils
  • 10. Skeletal muscle - Summary • Voluntary movement of skeletal parts • Spans joints and attached to skeleton • Multi-nucleated, striated, cylindrical fibres
  • 11. Smooth Muscle • No striations • Spindle shaped • Single nucleus • Involuntary- no conscious control • Found mainly in the walls of hollow organs
  • 12. Smooth muscle • Lines walls of viscera • Found in longitudinal or circular arrangement • Alternate contraction of circular & longitudinal muscle in the intestine leads to peristalsis
  • 13. Structure of smooth muscle • Spindle shaped uni-nucleated cells • Striations not observed • Actin and myosin filaments are present( protein fibers)
  • 14. Smooth muscle - Summary • Found in walls of hollow internal organs • Involuntary movement of internal organs • Elongated, spindle shaped fibre with single nucleus
  • 15. Cardiac Muscle • Striations • Branching cells • Involuntary • Found only in the heart • Usually has a single nucleus, but can have more than one
  • 16. Cardiac muscle • Main muscle of heart • Pumping mass of heart • Critical in humans • Heart muscle cells behave as one unit • Heart always contracts to it’s full extent
  • 17. Structure of cardiac muscle • Cardiac muscle cells (fibres) are short, branched and interconnected • Cells are striated & usually have 1 nucleus • Adjacent cardiac cells are joined via electrical synapses (gap junctions) • These gap junctions appear as dark lines and are called
  • 18. Cardiac muscle - Summary • Found in the heart • Involuntary rhythmic contraction • Branched, striated fibre with single nucleus and intercalated discs
  • 19. Muscle Control Type of muscle Nervous control Type of control Example SkeletalSkeletal Controlled by CNS Voluntary Lifting a glass Cardiac Regulated by ANS Involuntary Heart beating Smooth Controlled by ANS Involuntary Peristalsis
  • 20. Types of Responses • Twitch- – A single brief contraction – Not a normal muscle function • Tetanus – One contraction immediately followed by another – Muscle never completely returns to a relaxed state – Effects are compounded
  • 21. Where Does the Energy Come From? • Energy is stored in the muscles in the form of ATP • ATP comes from the breakdown of glucose during Cellular Respiration • This all happens in the Mitochondria of the cell • When a muscle is fatigued (tired) it is unable to contract because of lack of Oxygen
  • 22. How are Muscles Attached to Bone? • Origin-attachment to a movable bone • Insertion- attachment to an immovable bone • Muscles are always attached to at least 2 points • Movement is attained due to a muscle moving an attached bone
  • 23. Structure of Skeletal Muscle: Microstructure • Sarcolemma – Muscle cell membrane • Myofibrils – Threadlike strands within muscle fibers – Actin (thin filament) • Troponin • Tropomyosin – Myosin (thick filament)
  • 24.
  • 25. Structure of Skeletal Muscle: The Sarcomere • Further divisions of myofibrils – Z-line – A-band – I-band • Within the sarcoplasm – Sarcoplasmic reticulum • Storage sites for calcium – Transverse tubules – Terminal cisternae
  • 26. Sliding Filament Theory • Rest – uncharged ATP cross-bridge complex • Excitation-coupling – charged ATP cross- bridge complex, “turned on” • Contraction – actomyosin – ATP > ADP & Pi + energy • Recharging – reload cross-bridge with ATP • Relaxation – cross-bridges “turned off”
  • 27. The Sliding Filament Model of Muscle Contraction
  • 28.