This document summarizes research comparing the performance of single-core and multi-core processors when performing matrix multiplication. It finds that a multi-core processor, the Cell Broad Engine with 8 cores, was about 8 times faster than a single Power Processing Element core. However, performance began to decline for matrices larger than 2048x2048 due to data being swapped to disk. It also compares two multi-core programming models, Sequoia and Cellgen, finding Sequoia more stable but Cellgen having higher performance in other research.