The Most Contagious 2012 report discusses the evolution of branding and marketing, emphasizing the growing importance of purpose-driven approaches where brands operate as social citizens. It highlights trends such as the impact of social media, the integration of technology in retail, and the rise of crowdfunding platforms like Kickstarter. The document showcases successful examples of brands that have embraced their societal roles, offering meaningful services to consumers while navigating the changing landscape of business and communication.