Carl H. Rosner, CardioMag Imaging, Inc. - Speaker at the marcus evans Medical Device Manufacturing Summit Fall 2012, delivered his presentation entitled Modern Approaches to Heart Disease Detection
This document summarizes the findings of the AVOID study, which compared administering oxygen versus no oxygen to STEMI patients being transported for primary PCI. The study found that oxygen was associated with a 26% higher peak creatine kinase level, indicating larger infarct size on cardiac MRI. Oxygen was also linked to a higher rate of recurrent MIs but no difference in mortality. The AVOID study suggests administering oxygen to STEMI patients may increase infarct size and recurrent MIs compared to no supplemental oxygen.
1) The document provides guidelines for assessing patients presenting with symptoms of acute coronary syndrome (ACS). Signs and symptoms alone are not sensitive or specific enough for diagnosis.
2) An electrocardiogram (ECG) should be obtained as soon as possible and interpreted to identify changes suggestive of ACS. Cardiac biomarkers are also important for evaluation and need to be tested at 6 and 12 hours due to potential early negative results.
3) Chest pain observation units allowing clinical observation and serial testing are recommended to safely evaluate patients, reduce costs and lengths of stay compared to simple discharge decision rules. Imaging techniques also provide diagnostic and prognostic information but require consideration of risks.
This document summarizes guidelines for the diagnosis and treatment of acute coronary syndrome (ACS). It recommends prehospital ECG and notification to reduce time to treatment. For diagnostic markers, troponin combined with risk stratification can rule in or rule out ACS. It advises against routine supplemental oxygen for normoxic patients. For reperfusion, it emphasizes minimizing time to treatment and recommends primary PCI over fibrinolysis when it can be performed in a timely manner.
Lo mejor del Congreso ACC Chicago 2016
06/04/16 14:00 - 15:30h Casa del Corazón, Madrid
http://acc16.secardiologia.es
Lo mejor en insuficiencia cardiaca. #postACC16.
Dr. Alfonso Valle Muñoz, Hospital General Universitario Marina Alta, Denia (Alicante)
@ValleAlfonso
5 dan atar - anticoagulation and stroke prevention in afwebevo5
1. Anne is a 68-year-old woman with newly diagnosed paroxysmal atrial fibrillation and a CHA2DS2-VASc score of 2, placing her at intermediate risk for stroke.
2. Based on guidelines, NOAC therapy is recommended for stroke prevention given her risk factors of age and gender. All four NOACs would be suitable options for Anne based on her profile.
3. Given Anne's relatively low risk, a personalized approach focusing on patient education, involvement in decision-making, and lifestyle management is recommended. Regular follow-up will be important to monitor compliance, side effects, and adjust therapy if needed.
Perioperative cardiovascular assessment of patients undergoing noncardiac sur...kazi alam nowaz
Perioperative cardiovascular assessment is necessary for patients undergoing noncardiac surgery to evaluate medical status, cardiac risks, and recommend strategies to improve short and long term outcomes. Surgeries are stratified as low, intermediate, or high risk depending on the procedure. For patients at elevated risk, further testing like stress testing may be considered to guide management. Guidelines recommend continuing medications like beta blockers and statins perioperatively, as well as delaying surgery for patients with stents based on type. The timing and risks of surgery must be weighed based on a patient's cardiovascular condition and procedure.
The document discusses performing a pre-operative assessment of surgical patients to identify medical risks and stratify cardiac risk, outlines factors that increase perioperative cardiovascular risk including patient comorbidities, surgery type and functional status, and recommends tests and treatments to optimize patient safety for anesthesia and surgery.
This document discusses the use of B-type natriuretic peptide (BNP) testing in the evaluation of heart failure. It describes the physiology of BNP release and important caveats when interpreting BNP levels. Landmark trials are summarized that demonstrate the clinical utility of BNP for diagnosing heart failure, risk stratification of patients, and guiding heart failure management. The document recommends ordering BNP testing to help diagnose heart failure in patients with ambiguous signs and symptoms, as well as to track changes in patients' clinical status and risk over time.
This document summarizes the findings of the AVOID study, which compared administering oxygen versus no oxygen to STEMI patients being transported for primary PCI. The study found that oxygen was associated with a 26% higher peak creatine kinase level, indicating larger infarct size on cardiac MRI. Oxygen was also linked to a higher rate of recurrent MIs but no difference in mortality. The AVOID study suggests administering oxygen to STEMI patients may increase infarct size and recurrent MIs compared to no supplemental oxygen.
1) The document provides guidelines for assessing patients presenting with symptoms of acute coronary syndrome (ACS). Signs and symptoms alone are not sensitive or specific enough for diagnosis.
2) An electrocardiogram (ECG) should be obtained as soon as possible and interpreted to identify changes suggestive of ACS. Cardiac biomarkers are also important for evaluation and need to be tested at 6 and 12 hours due to potential early negative results.
3) Chest pain observation units allowing clinical observation and serial testing are recommended to safely evaluate patients, reduce costs and lengths of stay compared to simple discharge decision rules. Imaging techniques also provide diagnostic and prognostic information but require consideration of risks.
This document summarizes guidelines for the diagnosis and treatment of acute coronary syndrome (ACS). It recommends prehospital ECG and notification to reduce time to treatment. For diagnostic markers, troponin combined with risk stratification can rule in or rule out ACS. It advises against routine supplemental oxygen for normoxic patients. For reperfusion, it emphasizes minimizing time to treatment and recommends primary PCI over fibrinolysis when it can be performed in a timely manner.
Lo mejor del Congreso ACC Chicago 2016
06/04/16 14:00 - 15:30h Casa del Corazón, Madrid
http://acc16.secardiologia.es
Lo mejor en insuficiencia cardiaca. #postACC16.
Dr. Alfonso Valle Muñoz, Hospital General Universitario Marina Alta, Denia (Alicante)
@ValleAlfonso
5 dan atar - anticoagulation and stroke prevention in afwebevo5
1. Anne is a 68-year-old woman with newly diagnosed paroxysmal atrial fibrillation and a CHA2DS2-VASc score of 2, placing her at intermediate risk for stroke.
2. Based on guidelines, NOAC therapy is recommended for stroke prevention given her risk factors of age and gender. All four NOACs would be suitable options for Anne based on her profile.
3. Given Anne's relatively low risk, a personalized approach focusing on patient education, involvement in decision-making, and lifestyle management is recommended. Regular follow-up will be important to monitor compliance, side effects, and adjust therapy if needed.
Perioperative cardiovascular assessment of patients undergoing noncardiac sur...kazi alam nowaz
Perioperative cardiovascular assessment is necessary for patients undergoing noncardiac surgery to evaluate medical status, cardiac risks, and recommend strategies to improve short and long term outcomes. Surgeries are stratified as low, intermediate, or high risk depending on the procedure. For patients at elevated risk, further testing like stress testing may be considered to guide management. Guidelines recommend continuing medications like beta blockers and statins perioperatively, as well as delaying surgery for patients with stents based on type. The timing and risks of surgery must be weighed based on a patient's cardiovascular condition and procedure.
The document discusses performing a pre-operative assessment of surgical patients to identify medical risks and stratify cardiac risk, outlines factors that increase perioperative cardiovascular risk including patient comorbidities, surgery type and functional status, and recommends tests and treatments to optimize patient safety for anesthesia and surgery.
This document discusses the use of B-type natriuretic peptide (BNP) testing in the evaluation of heart failure. It describes the physiology of BNP release and important caveats when interpreting BNP levels. Landmark trials are summarized that demonstrate the clinical utility of BNP for diagnosing heart failure, risk stratification of patients, and guiding heart failure management. The document recommends ordering BNP testing to help diagnose heart failure in patients with ambiguous signs and symptoms, as well as to track changes in patients' clinical status and risk over time.
2018 AHA ASA guideline - guidelines for the early management of patients with...Vinh Pham Nguyen
The document provides guidelines for the early management of acute ischemic stroke, covering prehospital stroke management and systems of care, emergency evaluation and treatment, and in-hospital supportive care. It recommends public education on stroke signs and calling 911, designating stroke centers and teams, and using telemedicine to expand access to stroke expertise. The goal is to optimize early management through improved systems and rapid treatment to increase utilization of therapies like IV alteplase and endovascular procedures.
This document discusses preanesthetic evaluation and laboratory tests. It outlines the goals of preanesthetic evaluation which include reducing risk, screening for comorbid conditions, establishing baselines, identifying special needs, and obtaining informed consent. It describes components that should be included like medical history, physical exam, and specific tests. Timing of evaluation is discussed. The document also summarizes evaluation considerations for different patient populations like those with cardiovascular or pulmonary diseases, the elderly, and pregnant patients. Common preoperative tests are listed along with their indications.
This document provides guidelines for pre-operative evaluation and risk assessment. It discusses evaluating patients' medication use, medical conditions, functional status, and surgery-specific risk. Key factors that increase cardiac risk include recent heart attack, heart failure, diabetes, and poor functional status. Testing may be warranted for intermediate-high risk surgery or patients with a predicted >1% risk of major cardiac events. Continuation of most medications is reasonable. Statins, aspirin, and beta-blockers in selected patients can reduce risk. Timing of elective surgery depends on prior stenting or heart attack. The goal is to identify and optimize modifiable risks to reduce complications.
This document provides guidance on preoperative evaluation and preparation of patients undergoing anesthesia and surgery. It discusses performing a thorough history and physical exam to assess any medical conditions or risks that could impact anesthesia. The goals are to reduce patient risk, modify care as needed, and improve surgical outcomes. Key organ systems to evaluate include respiratory, cardiovascular, neurological, and endocrine. Relevant lab tests may be ordered depending on physical findings. The document also provides guidelines on preoperative preparation for conditions like diabetes and use of steroids to optimize patient health and safety during the perioperative period.
2014 accaha guideline on perioperative cardiovascular evaluation and manageme...alierstum
This document summarizes guidelines for perioperative cardiovascular evaluation and management of patients undergoing noncardiac surgery. It defines levels of surgical risk and urgency, and provides recommendations for evaluating and managing active cardiac conditions, clinical risk factors, valvular heart disease, arrhythmias, and pulmonary vascular disease before surgery. A stepwise approach is outlined to estimate perioperative risk based on clinical risk factors, surgical risk level, and objective measures of functional capacity. Further testing is only recommended if it could impact decision-making about proceeding with the planned surgery.
Non cardaic surgery preoperative cardiac evaluation aha esc guideline 2015rajasekar nagarajan
The document provides guidelines for preoperative evaluation of patients with cardiac disease undergoing noncardiac surgery. It discusses evaluating factors like the urgency of surgery, cardiac stability, and surgical risk level. Functional capacity is an important predictor of perioperative risk. Testing like ECG, echocardiogram, stress testing and angiography are recommended depending on the patient's risk level and functional capacity. Coronary revascularization before surgery is only recommended if indicated by existing guidelines. Overall preoperative evaluation and management depends on balancing cardiac and surgical risk on an individual basis.
preoperative evaluation for residents of anesthesia part 1mansoor masjedi
The document discusses the importance of preoperative evaluation in anesthesia. It notes that anesthesiologists now perform many roles beyond just anesthesia in the operating room, including focused clinical exams, medical optimization, reducing patient anxiety, and informed consent. A thorough preoperative evaluation can reduce surgical risks, delays and cancellations. Key aspects of the evaluation include assessing medical history and physical exam findings, laboratory tests, EKG, and risk classification using the ASA system. The goals are to identify health risks, heart conditions, optimize medical issues, and modify perioperative risk.
L box contemporary non-invasive cardiology testingAlysia Smith
Presentation by Lyndon C. Box, MD, FSCAI for the March 4 -6, 2016 Cardiac and Thoracic Surgery Associates, Cardiovascular Summit at The Westin Riverfront Resort and Spa.
Use of tPA for the Management of Acute Ischemic Stroke in the ED: ACEP PolicySun Yai-Cheng
ACEP Clinical Policy
Use of Intravenous Tissue Plasminogen Activator for the Management of Acute Ischemic Stroke in the Emergency Department
Ann Emerg Med. 2015;66:322-333
Ponencia presentada por el Prof. Niklas Nielsen en el CardioTV Live ‘Control de temperatura tras el TTM2’, realizado en la Casa del Corazón el 20 de septiembre de 2021.
Esc guidelines endocarditis by prof deldagowebevo5
This document discusses infective endocarditis, including its prevalence, mortality rate, prevention, diagnosis, treatment, and timing of intervention. It provides an overview of antibiotic prophylaxis guidelines and limitations. Case examples are presented to demonstrate diagnostic imaging modalities like CT and PET-CT. The importance of an infective endocarditis team approach involving multiple specialties is highlighted. Specific clinical situations that require emergent versus urgent versus elective surgery are also examined.
This study evaluated the addition of ticagrelor at doses of 90 mg or 60 mg twice daily to low-dose aspirin in reducing cardiovascular events in patients with a history of myocardial infarction 1 to 3 years prior. Over a median follow-up of 33 months, both ticagrelor doses significantly reduced the primary composite outcome of cardiovascular death, myocardial infarction, or stroke compared to placebo. However, both ticagrelor doses increased the risk of TIMI major bleeding compared to placebo. The 60 mg dose resulted in lower rates of bleeding and dyspnea with similar efficacy compared to the 90 mg dose.
ACC AHA Guidelines on Perioperative Cardiac AssesementMenaga Vasudewan
The ACC/AHA guidelines provide recommendations for preoperative cardiac risk assessment and perioperative management of noncardiac surgery patients. The guidelines classify patients into different risk levels based on 5 factors, including coronary history, prior cardiac testing, comorbidities, functional status, and surgery risk. They provide a 9 step algorithm to determine which patients need further cardiac testing or optimization of medical therapy prior to surgery based on their risk level. The guidelines aim to identify patients at high risk for cardiac complications from surgery and make recommendations to reduce surgical risk and improve outcomes.
How to perform pre-anaesthetic assessmentVetSpoke LTD
Pre Anaesthetic assessment is the first stage of anaesthesia. It is important to know that entry anaesthesia involves risk. It is the anaesthetist task to evaluate every patient's risk to optimise the perioperative management, reduce the risk, and improve the anaesthetic safety of the procedure.
For more information, Please visit:
https://www.vetspoke.com/
The document outlines the objectives and components of an anesthesia and CPR course for medical students. It covers pre-anesthesia assessment, orientation to anesthesia equipment, post-operative care, ICU rounds, and the role of anesthesiologists in the pre-operative period. Key topics include pre-anesthesia evaluation, anesthesia principles, medical history taking, risk stratification, airway evaluation, preoperative testing, informed consent, and documenting the preoperative visit.
The ALPHEUS trial compared ticagrelor to clopidogrel in reducing periprocedural myocardial injury in 1900 stable coronary patients undergoing high-risk elective PCI. Patients received a loading dose of either ticagrelor 180mg or clopidogrel 300-600mg before PCI, followed by 30 days of maintenance therapy. The primary outcome of periprocedural MI or major myocardial injury within 48 hours did not differ between groups. No differences were found in secondary outcomes including death or MI at 30 days. Ticagrelor did not increase major bleeding but was associated with more minor bleeding and dyspnea. The study concluded that higher platelet inhibition from ticagrelor did not translate to reduced per
The document discusses pre-anesthetic evaluation. It defines pre-anesthetic evaluation as the clinical foundation that guides preoperative patient management to reduce perioperative morbidity and enhance outcomes. It outlines the focused steps of pre-anesthetic evaluation which include taking a proper history and physical exam, documenting comorbidities, addressing patient anxiety, ordering investigations, discussing perioperative care plans, arranging postoperative care, and suggesting delaying or cancelling surgery if needed. The benefits outlined are more selective test ordering, reduced patient anxiety, improved acceptance of regional anesthesia, fewer cancellations, shorter hospital stays, and lower costs.
The document discusses preoperative care and provides guidelines on evaluating various body systems. It emphasizes performing a thorough history and physical examination to identify any medical conditions or risks. It also recommends specific tests and optimizations for different organ systems like cardiovascular, respiratory, gastrointestinal and others. The goal is to optimize the patient's health and minimize risks so they can undergo surgery safely.
1) A 7-year-old male child presented with a severe head injury after falling 4 stories, with an initial normal CT scan but gradually rising intracranial pressure.
2) The patient underwent an emergency decompressive craniectomy due to refractory elevated ICP, which improved his condition and he was successfully extubated on the third postoperative day.
3) An audit of over 2000 head injury patients at this trauma center over 18 months found that 53% had severe injuries, with an overall mortality of 22%, rising to 36% for severe injuries.
The document discusses the role of cardiac imaging in assessing patients with coronary artery disease (CAD). It provides examples of how cardiac imaging with techniques like myocardial perfusion scintigraphy (MPS), positron emission tomography (PET), and magnetic resonance imaging (MRI) can influence patient outcomes. Randomized controlled trials show that imaging-guided management and assessment of ischemia can improve outcomes compared to usual care. Imaging also enables equal diagnostic outcomes at lower cost compared to invasive procedures. Overall, cardiac imaging is presented as having a natural partnership with cardiology for evaluating CAD and guiding treatment.
The goal of this research project is to develop innovative, uncooled, unshielded sensors to record magnetic fields from the brain and heart for medical applications like magnetoencephalography and magnetocardiography. These new sensors will use nanoscale magnetoelectric composites and novel signal processing to allow detection of magnetic fields without cooling and determination of field direction. Researchers from various fields will collaborate to study the physical principles, fabrication, validation and applications of these sensors to advance medical research in neurology, cardiology and other areas.
El documento describe cómo el neuromarketing estudia los procesos cerebrales y cambios emocionales de las personas durante la toma de decisiones de compra. Identifica factores que influyen en la decisión de compra y herramientas como fMRI y EEG para medir las emociones de los consumidores. También establece variables que delimitan la influencia del neuromarketing en el proceso de decisión.
2018 AHA ASA guideline - guidelines for the early management of patients with...Vinh Pham Nguyen
The document provides guidelines for the early management of acute ischemic stroke, covering prehospital stroke management and systems of care, emergency evaluation and treatment, and in-hospital supportive care. It recommends public education on stroke signs and calling 911, designating stroke centers and teams, and using telemedicine to expand access to stroke expertise. The goal is to optimize early management through improved systems and rapid treatment to increase utilization of therapies like IV alteplase and endovascular procedures.
This document discusses preanesthetic evaluation and laboratory tests. It outlines the goals of preanesthetic evaluation which include reducing risk, screening for comorbid conditions, establishing baselines, identifying special needs, and obtaining informed consent. It describes components that should be included like medical history, physical exam, and specific tests. Timing of evaluation is discussed. The document also summarizes evaluation considerations for different patient populations like those with cardiovascular or pulmonary diseases, the elderly, and pregnant patients. Common preoperative tests are listed along with their indications.
This document provides guidelines for pre-operative evaluation and risk assessment. It discusses evaluating patients' medication use, medical conditions, functional status, and surgery-specific risk. Key factors that increase cardiac risk include recent heart attack, heart failure, diabetes, and poor functional status. Testing may be warranted for intermediate-high risk surgery or patients with a predicted >1% risk of major cardiac events. Continuation of most medications is reasonable. Statins, aspirin, and beta-blockers in selected patients can reduce risk. Timing of elective surgery depends on prior stenting or heart attack. The goal is to identify and optimize modifiable risks to reduce complications.
This document provides guidance on preoperative evaluation and preparation of patients undergoing anesthesia and surgery. It discusses performing a thorough history and physical exam to assess any medical conditions or risks that could impact anesthesia. The goals are to reduce patient risk, modify care as needed, and improve surgical outcomes. Key organ systems to evaluate include respiratory, cardiovascular, neurological, and endocrine. Relevant lab tests may be ordered depending on physical findings. The document also provides guidelines on preoperative preparation for conditions like diabetes and use of steroids to optimize patient health and safety during the perioperative period.
2014 accaha guideline on perioperative cardiovascular evaluation and manageme...alierstum
This document summarizes guidelines for perioperative cardiovascular evaluation and management of patients undergoing noncardiac surgery. It defines levels of surgical risk and urgency, and provides recommendations for evaluating and managing active cardiac conditions, clinical risk factors, valvular heart disease, arrhythmias, and pulmonary vascular disease before surgery. A stepwise approach is outlined to estimate perioperative risk based on clinical risk factors, surgical risk level, and objective measures of functional capacity. Further testing is only recommended if it could impact decision-making about proceeding with the planned surgery.
Non cardaic surgery preoperative cardiac evaluation aha esc guideline 2015rajasekar nagarajan
The document provides guidelines for preoperative evaluation of patients with cardiac disease undergoing noncardiac surgery. It discusses evaluating factors like the urgency of surgery, cardiac stability, and surgical risk level. Functional capacity is an important predictor of perioperative risk. Testing like ECG, echocardiogram, stress testing and angiography are recommended depending on the patient's risk level and functional capacity. Coronary revascularization before surgery is only recommended if indicated by existing guidelines. Overall preoperative evaluation and management depends on balancing cardiac and surgical risk on an individual basis.
preoperative evaluation for residents of anesthesia part 1mansoor masjedi
The document discusses the importance of preoperative evaluation in anesthesia. It notes that anesthesiologists now perform many roles beyond just anesthesia in the operating room, including focused clinical exams, medical optimization, reducing patient anxiety, and informed consent. A thorough preoperative evaluation can reduce surgical risks, delays and cancellations. Key aspects of the evaluation include assessing medical history and physical exam findings, laboratory tests, EKG, and risk classification using the ASA system. The goals are to identify health risks, heart conditions, optimize medical issues, and modify perioperative risk.
L box contemporary non-invasive cardiology testingAlysia Smith
Presentation by Lyndon C. Box, MD, FSCAI for the March 4 -6, 2016 Cardiac and Thoracic Surgery Associates, Cardiovascular Summit at The Westin Riverfront Resort and Spa.
Use of tPA for the Management of Acute Ischemic Stroke in the ED: ACEP PolicySun Yai-Cheng
ACEP Clinical Policy
Use of Intravenous Tissue Plasminogen Activator for the Management of Acute Ischemic Stroke in the Emergency Department
Ann Emerg Med. 2015;66:322-333
Ponencia presentada por el Prof. Niklas Nielsen en el CardioTV Live ‘Control de temperatura tras el TTM2’, realizado en la Casa del Corazón el 20 de septiembre de 2021.
Esc guidelines endocarditis by prof deldagowebevo5
This document discusses infective endocarditis, including its prevalence, mortality rate, prevention, diagnosis, treatment, and timing of intervention. It provides an overview of antibiotic prophylaxis guidelines and limitations. Case examples are presented to demonstrate diagnostic imaging modalities like CT and PET-CT. The importance of an infective endocarditis team approach involving multiple specialties is highlighted. Specific clinical situations that require emergent versus urgent versus elective surgery are also examined.
This study evaluated the addition of ticagrelor at doses of 90 mg or 60 mg twice daily to low-dose aspirin in reducing cardiovascular events in patients with a history of myocardial infarction 1 to 3 years prior. Over a median follow-up of 33 months, both ticagrelor doses significantly reduced the primary composite outcome of cardiovascular death, myocardial infarction, or stroke compared to placebo. However, both ticagrelor doses increased the risk of TIMI major bleeding compared to placebo. The 60 mg dose resulted in lower rates of bleeding and dyspnea with similar efficacy compared to the 90 mg dose.
ACC AHA Guidelines on Perioperative Cardiac AssesementMenaga Vasudewan
The ACC/AHA guidelines provide recommendations for preoperative cardiac risk assessment and perioperative management of noncardiac surgery patients. The guidelines classify patients into different risk levels based on 5 factors, including coronary history, prior cardiac testing, comorbidities, functional status, and surgery risk. They provide a 9 step algorithm to determine which patients need further cardiac testing or optimization of medical therapy prior to surgery based on their risk level. The guidelines aim to identify patients at high risk for cardiac complications from surgery and make recommendations to reduce surgical risk and improve outcomes.
How to perform pre-anaesthetic assessmentVetSpoke LTD
Pre Anaesthetic assessment is the first stage of anaesthesia. It is important to know that entry anaesthesia involves risk. It is the anaesthetist task to evaluate every patient's risk to optimise the perioperative management, reduce the risk, and improve the anaesthetic safety of the procedure.
For more information, Please visit:
https://www.vetspoke.com/
The document outlines the objectives and components of an anesthesia and CPR course for medical students. It covers pre-anesthesia assessment, orientation to anesthesia equipment, post-operative care, ICU rounds, and the role of anesthesiologists in the pre-operative period. Key topics include pre-anesthesia evaluation, anesthesia principles, medical history taking, risk stratification, airway evaluation, preoperative testing, informed consent, and documenting the preoperative visit.
The ALPHEUS trial compared ticagrelor to clopidogrel in reducing periprocedural myocardial injury in 1900 stable coronary patients undergoing high-risk elective PCI. Patients received a loading dose of either ticagrelor 180mg or clopidogrel 300-600mg before PCI, followed by 30 days of maintenance therapy. The primary outcome of periprocedural MI or major myocardial injury within 48 hours did not differ between groups. No differences were found in secondary outcomes including death or MI at 30 days. Ticagrelor did not increase major bleeding but was associated with more minor bleeding and dyspnea. The study concluded that higher platelet inhibition from ticagrelor did not translate to reduced per
The document discusses pre-anesthetic evaluation. It defines pre-anesthetic evaluation as the clinical foundation that guides preoperative patient management to reduce perioperative morbidity and enhance outcomes. It outlines the focused steps of pre-anesthetic evaluation which include taking a proper history and physical exam, documenting comorbidities, addressing patient anxiety, ordering investigations, discussing perioperative care plans, arranging postoperative care, and suggesting delaying or cancelling surgery if needed. The benefits outlined are more selective test ordering, reduced patient anxiety, improved acceptance of regional anesthesia, fewer cancellations, shorter hospital stays, and lower costs.
The document discusses preoperative care and provides guidelines on evaluating various body systems. It emphasizes performing a thorough history and physical examination to identify any medical conditions or risks. It also recommends specific tests and optimizations for different organ systems like cardiovascular, respiratory, gastrointestinal and others. The goal is to optimize the patient's health and minimize risks so they can undergo surgery safely.
1) A 7-year-old male child presented with a severe head injury after falling 4 stories, with an initial normal CT scan but gradually rising intracranial pressure.
2) The patient underwent an emergency decompressive craniectomy due to refractory elevated ICP, which improved his condition and he was successfully extubated on the third postoperative day.
3) An audit of over 2000 head injury patients at this trauma center over 18 months found that 53% had severe injuries, with an overall mortality of 22%, rising to 36% for severe injuries.
The document discusses the role of cardiac imaging in assessing patients with coronary artery disease (CAD). It provides examples of how cardiac imaging with techniques like myocardial perfusion scintigraphy (MPS), positron emission tomography (PET), and magnetic resonance imaging (MRI) can influence patient outcomes. Randomized controlled trials show that imaging-guided management and assessment of ischemia can improve outcomes compared to usual care. Imaging also enables equal diagnostic outcomes at lower cost compared to invasive procedures. Overall, cardiac imaging is presented as having a natural partnership with cardiology for evaluating CAD and guiding treatment.
The goal of this research project is to develop innovative, uncooled, unshielded sensors to record magnetic fields from the brain and heart for medical applications like magnetoencephalography and magnetocardiography. These new sensors will use nanoscale magnetoelectric composites and novel signal processing to allow detection of magnetic fields without cooling and determination of field direction. Researchers from various fields will collaborate to study the physical principles, fabrication, validation and applications of these sensors to advance medical research in neurology, cardiology and other areas.
El documento describe cómo el neuromarketing estudia los procesos cerebrales y cambios emocionales de las personas durante la toma de decisiones de compra. Identifica factores que influyen en la decisión de compra y herramientas como fMRI y EEG para medir las emociones de los consumidores. También establece variables que delimitan la influencia del neuromarketing en el proceso de decisión.
CHUUTI HOUSE IS A NEW COCEPT OF LEARNING AT HOME ,NEW HOBBY CENTRE AT RESIDENTIAL PLACE #182 SWASTIK VIHAR PATIALA ROAD ZIRAKPUR .9872895727,9779790833.ACTIVITY ART & CRAFT,YOGA,CAROM,CHESS,CALIGRAPHY,DECORATIVE ART,HOME FURNISHING AND MANY MORE.
This document discusses the importance of transforming and harmonizing energy quality in ourselves, products, and services. It notes that the heart generates the strongest electromagnetic field, driven by emotions, and that the brain's energy field can be measured by magnetoencephalography. Further, it suggests that products, people, and services should attract manifestations that vibrate at the same energy level. The goal is to consciously measure, monitor, and harmonize energy fields among people, products, and services. Additional information is available at the provided website.
MCG provides evidence-based care guidelines and software solutions to help providers, payors, and patients. Their solutions help determine the appropriate level and location of care, manage care to optimize recovery, and ensure successful transition from the hospital back into the community through monitoring and patient education. MCG independently develops their guidelines and solutions by comprehensively assessing the latest research and data to provide confident decision making support for right care.
Magnetoencefalografia y magnetocardiografia Marcelo Silami
This document discusses magnetoencephalography (MEG) and magnetocardiography (MCG). MEG is used in areas like epilepsy, Alzheimer's, and Parkinson's to help with pre-surgery planning. MCG has a sensitivity of 90.5% and specificity of 84.6% for detecting coronary artery disease in patients with normal electrocardiograms, outperforming tests like exercise electrocardiograms, Holter monitoring, and PET. The document provides references on uses of MCG like prenatal diagnosis of long QT syndrome and its current and future applications in clinical cardiology.
Electrocardiogram i.e ECG gives the exact idea about the proper functioning of the heart by specifying the PQRS waveform.This presentation specifies the methods of ECG measurement which are generally used.
The document discusses different types of noise that affect measurement accuracy, including thermal noise, shot noise, flicker noise, and interference. It explains how noise arises from random fluctuations in instruments and how it is characterized by its peak-to-peak amplitude and root-mean-square value. The key point is that the ratio of the signal to noise determines measurement ability, and factors like cooling, filtering, and modulation can be used to reduce noise and improve this ratio.
Magnetoencephalography (meg) and diffusion tensor imagingAdonis Sfera, MD
The document discusses using magnetoencephalography (MEG) and diffusion tensor imaging (DTI) to better diagnose mild traumatic brain injury (mTBI) and post-traumatic stress disorder (PTSD). Conventional imaging like CT and MRI often miss injuries from mTBI and find nothing abnormal for PTSD. MEG can detect abnormal low-frequency brain signals from injured areas in mTBI patients. DTI can find reduced anisotropy in white matter tracts, providing evidence of axonal injuries linked to areas generating MEG signals. Combining MEG and DTI findings provides stronger evidence of neuronal injury in mTBI than conventional imaging alone. MEG may also detect hyperactivated brain networks involved in PTSD
The document introduces FCI's MEG-Array connector system, which uses ball grid array (BGA) attachment. Key features include providing bandwidth of up to 5GHz for differential pairs, demonstrated solder joint reliability of over 22 years, and applications in servers, storage, switching, transmission, and industrial/medical equipment. FCI's patented BGA design provides perfect ball position and self-centering/leveling during reflow soldering to compensate for placement errors and ensure reliable connections.
Slides from an invited talk I gave at the MEG Basics series in the winter of 2012. Covers the theory behind signal processing techniques used in magnetoencephalography (MEG), including:
- Signal Space Projection (SSP)
- Signal Space Separation (SSS)
- Temporally-extended Signal Space Separation (tSSS)
- Principle Component Analysis (PCA)
- Independent Component Analysis (ICA)
Study of the release of heat by targeted gold nanoparticles exposed to RF fields. Study the physical properties of gold nanoparticles influence their RF thermal delivery which will aid in the further development of nanoscale materials for the treatment of cancer and various biomedical applications
1. Magnetoencephalography (MEG) is a functional neuroimaging technique that records magnetic fields produced by electrical currents in the brain to form a map of brain activity.
2. MEG uses very sensitive magnetometers like SQUIDs and SERF devices to detect magnetic fields from neural activity that are approximately 10 femto-Teslas in strength.
3. MEG measurements require magnetic shielding to reduce interference from external magnetic fields like the Earth's field, which is achieved using magnetically shielded rooms made of aluminum and mu-metal layers.
MEG measures magnetic fields produced by electrical activity in the brain. It provides high spatial resolution to localize brain regions activated during specific cognitive tasks and can help localize epileptic seizures. While MEG was first developed in the 1970s, advances over decades now allow it to map brain rhythms, language processing, connectivity between regions, and development from prenatal periods to learning. Key applications include epilepsy evaluation, mapping functional areas near brain tumors to guide surgery, and monitoring stroke recovery and chronic pain.
This document provides an overview of electrocardiograms (ECGs) including what they are used for, how they work, and how to interpret the different parts of an ECG tracing. An ECG is a test that records the heart's electrical activity through electrodes placed on the skin. It can be used to diagnose heart conditions by examining features such as intervals, waves, rates, and voltages. A normal ECG shows distinct P, QRS, and T waves along with standardized intervals between them. Abnormalities in the tracing can indicate issues like arrhythmias, enlarged heart chambers, or poor blood flow.
Salient features of the book are -
- The book provides a shortcut to understand and remember certain specific formulae and points you require to interpret the 12-lead ECG.
- Treatment protocols (in green boxes) for most of the important conditions are also included.
- View sample ECGs as you read along the topics.
- The content is explained in a very simple language to provide good conceptions, written from a student’s point of view.
- People can gain their belief in the book after going through sample ECGs which would be available at www.themedicalpost.net/ecg
- The book competes with the other books available in the market in simplicity, summaries, treatment protocols, live diagrams and regularly updated sample ECGs on the website.
La segmentación de mercado es el proceso de dividir un mercado en grupos más pequeños con características y necesidades similares. Estos segmentos son grupos homogéneos que probablemente responderán de manera similar a las estrategias de marketing. La segmentación sirve para determinar las características generales del consumidor objetivo de un producto. Existen diferentes tipos de segmentación como la geográfica, demográfica y conductual.
The document provides information about electrocardiography (ECG) including its history, how an ECG machine works, how to perform an ECG, ECG waveform interpretation, and common cardiac rhythms and abnormalities. It discusses key aspects of an ECG such as rate, rhythm, cardiac axis, P waves, PR interval, and common rhythms including normal sinus rhythm, atrial fibrillation, ventricular tachycardia, and more.
This document outlines the agenda and background for a proposal defense on examining the correlations between African American students' beliefs and academic outcomes. The study aims to explore how teachers' beliefs and school cultures affect African American students' attitudes, achievement, discipline referrals, and special education services. It will use a quantitative research design and collect data on students' and teachers' beliefs using instruments measuring stereotype threats, classroom environment, and discipline behaviors.
Exploring the Landscape: Choices and Decisions in IHD by Mustafa Toma, MD SM ...Providence Health Care
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3. Several cases are presented and treatment options of medical management, percutaneous coronary intervention (PCI), and coronary artery bypass grafting (CABG) are discussed in the context of each case based on symptoms, anatomy, and evidence from clinical trials.
The ICHOM Standard Set for Coronary Artery Disease defines outcomes that matter most to patients, including cardiovascular disease progression, patient-reported health status, acute complications, and survival. The document provides an overview of the standard set and measurement approach developed by physicians, measurement experts, and patients to improve understanding and treatment of coronary artery disease globally.
This document describes a heart disease and stroke prevention program from Cenegenics Medical Institute. The program uses advanced testing methods like genetic screening, ultrasound scans, and blood/urine biomarkers to comprehensively assess cardiovascular risk factors beyond what standard tests provide. It aims to prevent heart attacks, strokes, and other issues by identifying risks early. The evaluation involves blood draws, scans, and a physician consultation to review results and create a prevention plan. The program highlights its unique combination of advanced testing from partner laboratories to provide the most thorough risk assessment available.
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Los fármacos recomendados para iniciar el tratamiento antihipertensivo en este paciente son:
- Candesartán: por su demostrada capacidad para disminuir la hipertrofia ventricular izquierda y reducir la proteinuria, lo que es importante dado que el paciente presenta diabetes e hipertrofia ventricular.
- Telmisartán: al igual que el candesartán, ha demostrado reducir la proteinuria en pacientes diabéticos. Además, posee efecto antioxidante y antiaterogénico que son beneficiosos en este tipo de pacientes.
- V
Heart is the most important organ of a human body. It circulates oxygen and other vital nutrients through blood to different parts of the body and helps in the metabolic activities. Apart from this it also helps in removal of the metabolic wastes. Thus, even minor problems in heart can affect the whole organism. Researchers are diverting a lot of data analysis work for assisting the doctors to predict the heart problem. So, an analysis of the data related to different health problems and its functioning can help in predicting with a certain probability for the wellness of this organ. In this paper we have analysed the different prescribed data of 1094 patients from different parts of India. Using this data, we have built a model which gets trained using this data and tries to predict whether a new out-of-sample data has a probability of having any heart attack or not. This model can help in decision making along with the doctor to treat the patient well and creating a transparency between the doctor and the patient. In the validation set of the data, it’s not only the accuracy that the model has to take care, rather the True Positive Rate and False-Negative Rate along with the AUC-ROC helps in building/fixing the algorithm inside the model.
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Dr. Don Redelmeier presented on a study evaluating the use of catheter ablation for atrial fibrillation. The study included patients from the USA, EU and Australia between 2008-2016 who had symptomatic AF, intolerance to antiarrhythmics, and an LVEF ≤ 35%. The main result was that catheter ablation reduced the risk of all-cause mortality compared to antiarrhythmic drug therapy. However, the study had some limitations, including the potential for blinding failure and inadequate reporting of adverse effects. Overall the study scored 75% on the Sackett scale for validity and clinical applicability.
1) The document discusses the history and drivers of technology adoption in healthcare settings, including improving quality, safety, efficiency and empowering patients.
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3) Key stakeholders in healthcare IT certification are identified, including clinicians, vendors, payers, consumers, and government agencies.
World Heart Day 2023-Reperfusion Strategy.pptxdesktoppc
On the occasion of World Heart Day, a seminar was presented on reperfusion strategies for ST-elevation myocardial infarction (STEMI). Primary percutaneous coronary intervention (PCI) is the preferred reperfusion strategy when possible, as it improves outcomes over fibrinolysis. However, fibrinolysis may be considered in the "golden hour" if PCI cannot be performed within 120 minutes. A pharmaco-invasive approach involving initial fibrinolysis followed by urgent PCI can also be used when timely primary PCI is not available. The seminar discussed guidelines for optimal reperfusion times and management of STEMI to minimize heart damage.
Acute coronary syndrome result from a sudden blockage in a coronary artery. this blockage causes unstable angina or heart attack (MI), depending on the location and amount of blockage.
people who experience an ACS usually have chest pressure or ache, shortness of breath and fatigue.
People who think they are experiencing ACS should call for emergency help.
Doctors use ECG and blood test (troponin level) to determine whether a person is experiencing an ACS.
Treatment varies depending on the type of syndrome but usually include attempts to increase blood flow to affected area.
Remote Ischaemic Conditioning: A Paper Review & Uses in Paramedic Practicebgander23
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Cardiac Electrophysiology at the Minneapolis Heart Institute®Allina Health
By Raed H. Abdelhadi, MD. Examples of the cases seen by and the unique capabilities of the Complex Electrophysiology team at Minneapolis Heart Institute®.
The document provides information about cardiology and innovations in the field. It discusses:
1) Cardiology is concerned with diseases of the cardiovascular system. CVDs are the leading cause of death globally. In India, over 54.5 million people have CVDs.
2) The history of cardiology in India and globally, including important figures and firsts like the first open-heart surgery, pacemaker, and heart transplant.
3) Components of cardiac catheterization laboratories, their purpose, equipment, and staff requirements. Administrative issues regarding utilization, performance evaluation, and quality assurance are also covered.
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JNC8 Guidelines for Management of HypertensionAhmed Mahdy
This document discusses evidence-based treatment strategies for hypertension. It summarizes recent clinical trials that have evaluated optimal blood pressure goals for different populations, such as those with diabetes or coronary artery disease. The document notes that while guidelines recommend lower blood pressure targets for certain high-risk groups, some trials have found no clear cardiovascular benefit and even potential harm from overly intensive control. It emphasizes using the hierarchy of evidence and balancing clinical evidence with patient preferences in individualizing treatment.
The document discusses various diseases of the adrenal glands, including adrenal insufficiency, Cushing's syndrome, hyperaldosteronism, pheochromocytoma, and congenital adrenal hyperplasia. It provides details on the causes, clinical presentations, diagnoses, and treatments for each condition. Key learning points are emphasized, such as the need for lifelong glucocorticoid replacement therapy in adrenal insufficiency and the importance of excluding pheochromocytoma prior to surgery due to risk of hypertensive crisis. Clinical cases are presented and answered to demonstrate application of knowledge.
This document summarizes recent advancements in healthcare devices and pharmaceutical products by Abbott Laboratories. It discusses Abbott's nutrition care products including oral rehydration drinks, diabetes care technologies like continuous glucose monitors, diagnostics tests like BinaxNOW tests for COVID-19, heart health devices, and neuromodulation systems for pain management like Proclaim DRG neurostimulation. Abbott was established in 1910 and specializes in products for cardiovascular health, diagnostics, diabetes, and pain treatment, impacting over 100,000 people globally.
Similar to Modern Approaches to Heart Disease Detection - Carl H. Rosner, CardioMag Imaging, Inc. (20)
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A global, multifaceted media, corporate marketing and information company, employing 3000 professionals in 59 worldwide locations. Our activities are wide ranging, providing up-to-the-minute information for businesses and professionals worldwide.
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Country of origin labelling (COOL) aims to provide transparency around where foods originate from but its implementation is complex. COOL regulations differ between countries and can be challenging for food businesses to comply with due to globalized supply chains. While COOL does not directly relate to food safety, adhering to its rules helps ensure strong traceability systems. There is ongoing debate around the costs and benefits of COOL for both consumers and businesses.
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Undeclared allergens continue to be a major challenge in the global food industry due to complex supply chains and changing consumer habits. Allergens can contaminate foods at many stages of production from farms to packaging. Strict management practices are needed to control for allergens, including accurate labeling and segregating allergenic and non-allergenic production areas, but contamination risks remain. Emerging issues like new "free from" product demands and packaging that is not easily distinguishable further complicate allergen management. Vigilant monitoring of all supply chain participants is key to reducing the risk of unexpected allergens in foods.
The document discusses the importance of developing a strong food safety and quality culture within food businesses. It states that a good culture can improve productivity, quality, reduce costs and provide competitive advantages. It identifies several key requirements for establishing a strong culture, including senior management commitment, clear strategies and policies, defined roles, integrated teams, training, measurements, and adapting to changes. The document emphasizes that culture requires constant attention and commitment to develop and maintain.
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Modern Approaches to Heart Disease Detection - Carl H. Rosner, CardioMag Imaging, Inc.
1. Modern Approaches to Heart Disease Detection
pp
Medical Device Presentation
Carl H. Rosner
November 2012
CardioMag Has Developed A Key to
Prevention and Avoidance of Heart Attacks
CONFIDENTIAL/PROPRIETARY NOTICE: This presentation contains p p
p proprietary information of CardioMag Imaging, Inc. It is for use only as directed by
y g g g, y y
CardioMag, and may not be used for any other purpose or disclosed to others or reproduced, in whole or in part, without CardioMag’s prior written authorization.
Statements presented in this presentation which are not historical fact are forward looking statements which involve various important assumptions, risk,
uncertainties and other factors set forth herein, including but not limited to, obtaining additional FDA clearance, market acceptance, insurance companies
reimbursement policies on particular diagnostic applications and the growth of customer acceptance. Given these uncertainties, readers of this presentation are
cautioned not to place any undue reliance on such forward looking statements. The Company disclaims any obligation to update any such forward looking
statements in this document to reflect future events or developments.
2. OVERVIEW of Presentation
• Causes of Heart Disease
• Progress Over Past Decade
• Heart Disease in America
• List of Cardiology Societies
• More Statistics
• Approach to Patient Evaluation/Treatment
• Ideal Solution to Avoid Heart Attacks and Possibly Other Procedures
• IT IS HERE! - MagnetoCardioGraphy (MCG)
• Existing Technologies
• MCG Equipment View
• Test Information
• Economic Benefits
• Clinical Results
• Publications
• Suitable for Testing Everybody, Especially Women, Athletes and Children
• Conclusion
3. GENERAL AGREEMENT: Causes of Heart Disease (CVD)
I. KEY PROBLEM – As People Age – Their Heart Ages
II. FAMILY HERITAGE – Plus Individual Characteristics and Behavior
- High Blood Pressure
- High Cholesterol
- Diabetes
- Obesity
- Physical Inactivity / OR too much
- Poor Diet
- Excessive Alcohol Use
- Smoking
- Inadequate Sleep
4. INTRODUCTION
ENORMOUS PROGRESS OVER PAST DECADE IN:
Exciting New Technologies Continually Being Pursued
• Evaluating Heart Disease Non-Invasively
Non Invasively
• Treating Heart Disease with Pharmaceuticals
• Treatments of Heart Disease with Invasive Procedures
• Opening Clogged Arteries with Stents
• By-Pass Operations – Replacing Arteries
• Replacements of Entire Hearts
YET
1. Almost 1 Million Americans per year have Heart Attacks
or Stroke – of whom almost 500,000 DIE.
1.
1 Cardiologists know that about 90 Percent of Heart Attacks are
Preventable!!
2. What Needs To Be Done to Accomplish Such A Goal?
5. Heart Disease in America – The Epidemic
The Hidden Epidemic: Heart Disease in America
“Heart disease is the number one killer in
America and one of the nation’s greatest
health challenges for both men and women.
More than half of all people who die of heart
disease succumb suddenly without warning -
and the other half have the disease lurking in
their body for many years before it strikes. “
Phillip, 44, worked out played golf, and died suddenly of a massive heart attack.
Pat,
Pat 57, did ’t know she h d hi h bl d pressure and di b t – until th lled t h h t attack.
didn’t k h had high blood d diabetes til they d to her heart tt k
Robin, 42, knew that an inherited form of high cholesterol put her at risk, but her first of multiple heart
attacks caught her by surprise.
7. GENERAL AGREEMENT: Reduce Heart Disease (CVD)
III. Cardiologists’ Approach Today (Generally)
- Check Blood Pressure once a year
- Check Weight
- Measure EKG Diagram – 12 Leads
- Admonish patient to observe healthy life styles
- Recommend Daily Dose of Aspirin
- Prescribe – if Necessary – Cholesterol lowering drugs
- Prescribe – if Necessary – Blood Pressure lowering drugs
- If indicators are serious – proceed to invasive procedures such
as CT, Nuclear Stress Tests, Angiography or more
IV.
IV Newer Methods (Work in Progress)
- Functional MRI
- Meditation
- Stem Cells Plus Others
8. CARDIOLOGY AND CARDIOVASCULAR PROFESSIONAL
SOCIETIES AND ASSOCIATIONS
• The American Heart Association
• American College of Cardiology
• Heart Failure Society of America (HFSA)
• American Society of Echocardiography (ASE)
• Alliance of Cardiovascular Professionals (ACVP)
• American College of Chest Physicians (ACCP)
• Society f I
S i t of Invasive Cardiovascular P f
i C di l Professionals (SICP)
i l
• American Association of Heart Failure Nurses (AAHFN)
• Cardiovascular Credentialing International (CCI)
• American Society of Nuclear Cardiology (ASNC)
• National Heart, Lung and Blood Institute
• WomenHeart
• World Heart Federation
• The National Heart Forum
• Cardia Arrhythmias Research and Education Foundation (CARE)
• Children’s Heart Association
9. Existing Technology Limitations
The quick tests (EKG, blood tests)
• lack accuracy – delayed results
y y Indications of a heart attack include
sweating, anxiety and chest pains
The expensive tests (SPECT, MRI, CT)
• Take too long - Cells DIE if MI
• Require specialists to perform
• Not usually available 24/7
• S
Some also i
l involve i j ti of
l injection f
radioactive chemicals
• Some involve very heavy doses of
x-rays or Gamma rays
10. MORE STATISTICS
1. The U.S. spends about $300 Billion on Heart
Disease Annually! y
2. Twice as many women than men die from Heart
Attacks.
3. The initial test for Heart Disease is the over 100
year old EKG (which is about 40 – 50 percent
accurate).
4. Heart Dysfunction often leads to Stroke.
5. Many more men and women die from Heart
Disease than from Cancer.
11. MAGNETOCARDIOGRAPHY (MCG) EXPLAINED
New Approach To Heart Health Testing
MagnetoCardioGraphy is the continuous recording of the magnetic fields
created by cardiac electric activity.
MCG sensors do not contact the patient who can remain dressed.
MCG is entirely non-invasive with no injections or radiation required.
Test results for existence or absence of Cardiac Dysfunction are displayed
within 15 minutes from beginning of procedure.
12. INITIAL VALUE PROPOSITION
11.2 million chest pain visits to the Emergency Room each year
7 million admissions 4.2 million discharged
4,900,000 no ACS* 700,000 MI 210,000 missed MI†
Billions of $ in excess costs >1 in 9 will die in 30 days
MCG can save MCG can save a life
$5000 per patient every thirty minutes
*Acute Coronary Syndrome †Myocardial Infarction
13. SYSTEM PARAMETERS NEEDED TO REDUCE HEART DISEASE
• Organize Prevention Program (Develop Compensation)
• Early Detection of Cardiac Dysfunction
• Early Treatment (Still Relatively Inexpensive)
• Regular Monitoring of Functional Cardiac Changes
• Patient Can Remain Dressed
• Test Procedure Less Than 10 – 15 Minutes
• Results Available in Real-Time Immediately Thereafter
• Equipment Can be Operated by Nurse/Technician
• Test Totally Safe – No Injections or Radiation
• Test Over 90 Percent Accurate
• Test Recordings In Visual Color Format
• Remotely Readable
• FDA Approved – Needs Recognition By Medical Societies
• Insurance Needs to Pay For Tests
• Periodic Tests d Early Treatment A id H t Att k
P i di T t and E l T t t Avoid Heart Attacks
14. The CardioMag MCG System*
* FDA Cleared
•No radiation
No
•No biohazards
•No injections
•24x7 operation
•Patient at rest
•15 minute test
•Quantitative results
Q tit ti lt
CLEEARED
15. CardioMag’s New Cardiac Diagnostic Technology
Offers Major Benefits To:
• PATIENTS – No Radiation, Non-Invasive Test
• CARDIOLOGISTS – Earn More Money
• HOSPITALS – Increased Incomes
• INVESTORS – High Return on Investment
g
• INSURANCE CO’S – Reduced Expenses/Costs
10 Minute Test is Safe Results are Immediate
Safe,
5th Year Goal – Population Screening: Early Detection of Heart Disease
16. Company Information
• CardioMag Imaging Inc. formed in 1999; Delaware Incorporation
• 2004 – FDA Clearance, CE mark in Europe for MCG
Clearance
• 2005 – Med. Device Reg. in China, Russia
• 2005 – Raised $ 7,200,000 (Net) – London / AIM Exchange
• 2006 – Left AIM Exchange – No Realistic Benefits
• 2007 - Audited Statements Available Since 2001
• 2008 - Marketable Systems Available For Installation
• 2012 - More Patents – US and Internationally
CardioMag Has: 12,000,000 Shares Outstanding
Approx.
Approx 120 shareholders
$23 Million Tax Loss CarryForward
CardioMag is inviting a limited number of sophisticated investors to join the
Company’s shareholders.
17. The MCG Measurement
Preparation
• Remove metallic items
• Connect 3 ECG leads
• Rough positioning
• Fine positioning using
laser pointer
• Lower sensors
• Lock bed
oc
19. Heart disease = fingerprint in MCG
Example: Colour magnetic field maps during repolarization
Normal 100% LCX 3 vessel disease
Normal := homogeneous, stable, correct orientation
Abnormal := inhomogeneous, dynamic, wrong orientation
20. Economic Benefits to Hospitals / Clinics
•Scanner th
S throughput up to 5000 per year ( <15 min / patient t t )
h t t 15 i ti t test
– Just $300 per test yields $1,500,000 revenue
•Improved worker productivity (less lost time out of office)e)
p p y( ) )
•Catch disease earlier while amenable to aggressive medical therapy
•Faster turnover of beds (avoid ER overcrowding)
Faster overcrowding),
more efficient use of resources
• Capture more DRG value – Avoid multiple diagnostic procedures
g
•Increase Cathlab Volume, especially with patients needing intervention
•Keep lower risk cardiology patients from being sent to another hospital
•Avoid litigation (inadvertent discharge of patient with MI)
21. Published Clinical Results - Example
Park et al*: “The high predictive values of the admission
MCG could make it possible to more accurately and in a
very early stage select [ACS] patients who should proceed
quickly to invasive coronary angiography.”
Sensitivity
y 95.1 %
Specificity 92.8 %
PPV 97.8 %
NPV 84.8
84 8 %
No. of Patients 185
Published in : A.N.E. 10(3):1–12, April 2005
*Jai-Wun Park, Peter M. Hill, Namsik Chung, Paul G. Hugenholtz, and Friedrich Jung
Hoyerswerda Hospital, Germany; Johns Hopkins University; Yonsei University, Seoul, Korea; Erasmus University,
Rotterdam, The Netherlands; Institute for Heart - and Circulation Research, Hoyerswerda, Germany; University of
Saarland, Homburg/Saar, Germany
22. Publications/Talks are Increasing
• Magnetocardiography study on ventricular depolarization-current pattern in patients with brugada syndrome
and complete right-bundle branch blocks [Pacing Clin. EP]
• Comparison of magnetocardiography and electrocardiography: a study of automatic measurement of
dispersion of ventricular repolarization [Europace]
• QRS duration in high-resolution methods and standard ECG in risk assessment after first and recurrent
myocardial infarctions [Pacing Clin. EP]
• Magnetocardiographic assessment of healed myocardial infarction [ANE]
• Three-dimensional recovery time dispersion map by 64-channel magnetocardiography may demonstrate
the location of a myocardial injury and heterogeneity of repolarization [Int Jrl CV Imaging]
• Magnetocardiography changes in coronary artery disease patients with normal or unspecialized resting
electrocardiogram [Chinese Jrl of CV Disease]
• Magnetocardiographic diagnosis for myocardial ischemia and arrhythmias [Clin Disease Science]
• Increased intra-QRS fragmentation in magnetocardiography as a predictor of arrhythmic events and
intra QRS
mortality in patients with cardiac dysfunction after myocardial infarction [Jrl CV EP]
• Magnetocardiographic markers of functional hemodynamic overloading of the right atrium [Aviakosm
Ekolog Med ]
• Identification of patients with coronary artery disease using magnetocardiographic signal analysis
[Biomed Tech]
• Non-invasive resting magnetocardiographic imaging for the rapid detection of ischemia in subjects
presenting with chest pain [Cardiology]
• Electrical space-time abnormalities of ventricular depolarization in patients with Brugada syndrome and
patients with complete right-bundle branch blocks studied by magnetocardiography [Pacing Clin. EP]
23. Athletes Advised to Take Heart Tests
Screening could be an entry requirement for competitions
Athletes should be screened for heart conditions before taking part in sporting competitions, a coroner has said.
Columbia Football to Participate in Heart Screening Program
Screening and treatment are necessary to meet
the i i
th rising problem of obesity in th U it d
bl f b it i the United
States, the task force said …
24. A SOLUTION FOR 21ST CENTURY
CARDIOLOGISTS ‘SEE’ HEART FUNCTIONS
25. CONCLUSION
• Magnetocardiography (MCG): a sophisticated new technology that
provides rapid, unique and valuable information about early signs of
heart disease in a safe and Radiation-Free Patient and Physician
Radiation Free
environment.
– The technique relies on analyzing magnetic fields generated by the
heart s
heart’s electrical activity and quantitatively measuring dynamic
behavior of ventricular repolarization.
– Using this information a physician can determine the earliest of risk
that a patient might have coronary artery disease and -- for some
patients -- the relative risk of sudden cardiac death.
• MCG Complements and adds to Existing Technology
• MCG creates a New Market Space in large Cap-Ex Area of Cardiac
Diagnostics to favorably impact HealthCare Costs, saving $ Billions.
26. Thank You
13 British American Blvd.
Latham, NY 12110
L th
518-381-1000
www.cardiomag.com