Presentation by Miki Halberthal, CEO, Rambam Health Care Campus, for the mHealth Israel community, May, 2020. Includes Rambam financials, sector growth, innovation into practice, ingredients of success, overview of Rambam Innovation Hub, tech transfer, bio bank, clinical research, clinical trials, medtech, CoVID response, etc

1. The future of Hospitals
Webinar: Hospitals pivot to the future – Focus on India
May 12, 2020
Rambam Health Care Campus
Haifa, ISRAEL
assis Prof. Michael Halberthal MD, MHA
Director General & CEO

3. Facts & Figures
2019
1042 Beds +57 Day Care
1,226Physicians
1,732Nurses
1,089 Allied health care
professionals
1,259 Household and
administrative staff
=================
5,306 Total employees

4. Facts & Figures
2019
144,447 Emergency Department Visits
83,639 Inpatient Admissions
741,012 Outpatient Visits
39,520 Surgical Pts.
4,698 Births
287,487 Imaging Procedures
1,932 Clinical Research
Studies

5. Rambam Financials: 2019 Budget*
Hospital Health Corporation Total
Income
366 145 511
Salaries & Related Expenses
278 83 361
Operating Expenses
116 61 177
Construction & Buildings Refurbishment
3
5*Amounts are in US$ Million

6. Bloomberg Business
By: Lee J. Miller & Wei Lu September 19,2018
Canada
16
USA
54
France
17
UK
35
Netherlands
28
5.7%
4.3%
9.2%
9.0%
7.4%
7.4%
10.9%
9.4%
6.2%
3.5%
China 5.3%
28
11.1%
10.7%
XX = %GDP
World-10.021% (2016)
9.9%
10.4%
16.8%
India 3.66%

7. Synergy for Success
7
Collaboration & Technology Transfer
Engineers
Physicians
Scientists
Funding

8. Growth per Sector
8

9. Medical knowledge
9

10. MD time consuming
10

11. Medicine: Past Vs. Future
FutureConservative
Concentrating on healthConcentrating on illness
ExponentialSlow
DigitalPersonal
“Customer” Concept“Patient” concept
Tailor madeHerd medicine
Patient owned dataMedical system owned data
Moore’s lawSlow and expensive
Holistic team work AIFamily doctor
Home careHospital care
11

12. Saving the Endangered Physician-Scientist
— A Plan for Accelerating Medical Breakthroughs
Mukesh K. Jain, M.D., Vivian G. Cheung, M.D., Paul J. Utz, M.D., Brian K. Kobilka, M.D., Tadataka Yamada, M.D., and Robert Lefkowitz, M.D.
12
(nejm 381;5 nejm.org August 1, 2019)
Physician – Scientist in USA (4 decades)
4.7% →1.5%

13. Innovation into practice
13

14. Collaborative Communication
14

15. Beyar, R., Zeevi, B., & Rechavi, G. (2017). Israel: a start-up life science
nation. The Lancet, 389(10088), 2563-2569.
Ingredients of Success

17. Rambam Innovation Hub

18. RAMBAM AS IT LEADER
SELF DEVELOPED
Prometheus EMR system
E-mergency
Emergency situation
management
Insight
Information system for
hospital managers
Adam
Computerized
personnel controller

19. BRINGING INNOVATION
TO MARKET

20. WORLDWIDE SUCCESS STORIES
Hybrid SPECT/CT
and PET/CT
Cardiac Electrical
Mapping
PillCam
Given Imaging
MRI / US fusion

21. SUCCESS STORIES | TECH TRANSFER
Robotic-assisted PCI Cardiac Electrical
Mapping
Micro-robotic
Technologies
PUBLICLY TRADED

22. Transapical approach Multiple biopsy FNA
Stem Cells
Technologies
Infant nutrition
Diabetes Retina
protection
Ischemic Stroke Rx
SUCCESS STORIES | TECH TRANSFER
PRE-SALES
SALES

23. BIOBANK
Collection events
Individual donors
Samples
Frozen tissue (tumors + benign)
Bone marrow
Blood (serum, plasma, whole blood)
Within 4 Years
Capability to link between the Bio sample and the patient (EMR)

24. CLINICAL RESEARCH INSTITUTE AT RAMBAM
TRANSLATING MEDICAL NEEDS INTO RESEARCH
Clinical Scientists
Medical expertise
Research Know-how

26. EARLY PHASE RESEARCH
ONE STOP SHOP
Designated team
Initial consulting on
study design
FIM & Trial execution

27. DISCOVERY TOWER

28. DISCOVERY TOWER
Future home for applied
medical research
Daily interplay between clinicians,
researchers and the industry
Participants
Rambam's physicians-scientists
Researchers from the Technion
and Haifa Uni.
Biomedical industry startups,
strategics

29. RAMBAM MEDTECH )TECHNOLGY TRANSFER(
CREATING VALUE FOR INNOVATORS

30. Co-investor - Managing $40M
[VC and impact 1st investments]
SINCE 2016: 8 active companies.
Goal – 40 companies in 8 years
MINDUP | HAIFA'S DIGITAL HEALTH INCUBATOR
Launchpad to market

31. World Economic Forum:
Global risk report 2020

32. WEF: The global risk landscape
2020

33. 33
Rambam Campus | June 2017

34. Rambam on the
Frontline Fighting
COVID-19
Rambam on the
Frontline Fighting
COVID-19

35. On the Frontline Fighting COVID-19
RHCC Solution for COVID-19
Phase 1: Negative pressure isolation room
Phase 2: “Crown” Department A: 30 patients, 6 ICU
Phase 3: “Crown” Department B: Total 66 patients,
32 ICU (extension 12 ICU)
Phase 4: Sammy Ofer Fortified Underground
Emergency Hospital: 900 patients, 300 ICU

36. Control and Monitoring Systems:
Elbit
Unmet Need:
Controlling staff and patients in challenging surrounding
Solution:
• A military system designated for command and control
• Provides advanced communication
• Management and organizational capabilities – and excellent crisis management tool
• Identification of patients – mode of treatment
On the Frontline Fighting COVID-19

37. Control and Monitoring Systems:
The CoView System
Unmet Need:
Operational data collection and control for
decision makers
Solution:
• Display snapshots of personnel data,
critical equipment tracking, patients’
status
• Build onto online information in existing
hospital systems
• Inter- and intra-
hospital connections
• Administrative system
• logistics system
• attendance system
• Clinical data – monitors & Vents
On the Frontline Fighting COVID-19

38. Control and Monitoring Systems:
Rafael - Rstream
Unmet Need:
Medical equipment collecting monitoring data
Solution:
• Active online system the collects data from
monitors, vents, infusion pumps
• Using picture processing or direct
connection
• Every vendor generic solution
Rafael’s Imaging/Data System
On the Frontline Fighting COVID-19

39. Medical & Hi-Tech Collaboration
• Goal: Optimal patient care
with minimal potential for
staff contamination
• Solution: Implement digital
patient monitoring and
innovative use of pre-existing
equipment
On the Frontline Fighting COVID-19
Digital Monitoring of Patients
Patients can
converse with
staff as
needed

40. Diagnosis: Technion
Unmet Need:
Measure diagnosis of COVID-19 technology during limited lab resources
Solution:
Pooling clinical RNA samples – 32 (64?) samples in one go
On the Frontline Fighting COVID-19

41. Diagnosis
Unmet Need:
Early recognition of respiratory
failure, ARDS in COVID-19 patients
Solution:
• Speech analytics: Analyze
recordings a patient’s voice
• ReDS™ system - measures lung
fluids
On the Frontline Fighting COVID-19

42. Personal Protective Equipment (PPE)
Unmet Need:
Staff protection and
convenience
Solution:
• IDF: New head/neck cover
manufactured and tested at
RHCC
• IDF: Alternative polyester
gown with internal ventilation
On the Frontline Fighting COVID-19

43. Assessment of the protection capabilities of PPE
On the Frontline Fighting COVID-19

44. • Introduction of new face shield that creates
an active protective mask.
• The face covering is attached to a pump
that sends filtered air into the mask,
creating an "air curtain" that prevents
inhalation of viruses and bacteria
• Used together with an N95 mask, provides
close to 100% protection against inhaled
particles (Technion)
Personal Protective Equipment (PPE)

45. Telemedicine - Datos

47. 47
T
h
a
n
k
y
o
u