XRHealth is revolutionizing healthcare, bringing patient care into the Metaverse. Includes a description of the TeleHealth Platform. Lessons Learned – Building the clinical Metaverse. Last mile delivery Building a product in the Metaverse is easy – getting people to use it is hard. Virtual Care can’t be based only on XR. HMDs bring friction – Charging, Guardian, Safety, Passwords etc. Expanding virtually in a brick & mortar payer environment. Once you cross the chasm – adherence/ satisfaction/retention goes ballistic. Patient Outcomes- Patients report significant improvement in symptoms following treatment. Adherence - patients follow Home Exercise Plans as prescribed. 92.2% with XRHealth vs 50% with regular treatment. Patient satisfaction - 85 NPS vs 38 NPS in healthcare 93.3% patient retention -complete treatment cycle as prescribed. XRHealth Luna AI Reduces Hot Flashes and Improves Psychological Well-Being in Women with Breast and Ovarian Cancer: A Pilot Study. Virtual reality immersion compared to monitored anesthesia care for hand surgery: A randomized controlled trial. Lessons Learned – Autism Spectrum Disorder. The future of the Mediverse.

1. April 2023
Confidential and Proprietary
Virtual Treatment Rooms
of the Metaverse
Miki Levy
Co-Founder & CTO
miki@xr.health

2. Confidential and Proprietary 2
Confidential and Proprietary
XRHealth is revolutionizing
healthcare, bringing patient
care into the Metaverse
4 fully operational virtual clinics:
MA, FL, MI, Australia
reimbursed by most major payers,
Medicare and private
Fully operational Virtual
Treatment Rooms Platform for
chronic conditions
FDA, AMAR and CE
Registered
6K patients treated
300K VR sessions completed
VR session every 7 mins
Patient Adherence - 92%
Patient retention - 93%
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2
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3. Patient completes an initial evaluation and
is sent a Telehealth XR kit, preloaded
with XR Medical applications and
treatment plan
Telehealth sessions held twice a week.
Clinician uses External Control app to
control patient’s VR headset
Patient uses Mobile App
to track progress and chat with the
clinician. Clinician monitors patient
progress using the Data Portal
Patient’s insurance company is billed
for telehealth visits and Remote
Therapeutic Monitoring
XR Medical
Applications
XR
Telehealth
Kit
Patient
Mobile
App
Clinician
External Control
& Data Portal
Patients Clinicians
3
Confidential and Proprietary
The Platform
Video:
How it
Works

4. Confidential and Proprietary
Confidential and Proprietary
Lessons Learned – Building the clinical Metaverse
Last mile delivery
• Building a product in the Metaverse is easy – getting people to use it is hard
• Virtual Care can’t be based only on XR
• HMDs bring friction – Charging, Guardian, Safety, Passwords etc.
• Expanding virtually in a brick & mortar payer environment
• Once you cross the chasm – adherence/satisfaction/retention goes ballistic
Patient Outcomes
• Patients report significant improvement in symptoms following treatment
• Adherence - patients follow Home Exercise Plans as prescribed. 92.2% with
XRHealth vs 50% with regular treatment
• Patient satisfaction - 85 NPS vs 38 NPS in healthcare
• 93.3% patient retention - complete treatment cycle as prescribed

5. Confidential and Proprietary 5
XRHealth Luna AI Reduces Hot Flashes and Improves Psychological Well-Being in Women
with Breast and Ovarian Cancer: A Pilot Study
Clinical study results:
• Between pre- and post-intervention, participants reported a significant reduction in
the daily frequency of hot flashes, stress, general psychiatric distress, several
domains of QOL, and sleep difficulties, as well as an improvement in illness
perception.
• In addition, they reported very high satisfaction with Luna. Importantly, both age
and baseline levels of psychopathology moderated the effect of Luna on sleep
difficulties.
Methods:
42 women with breast and/or ovarian cancer. The mean age was 47 years. Patients suffered from hot flashes at different frequencies. They used Luna, a
virtual reality (VR) mobile psychological intervention based on elements from both cognitive behavioral therapy and mindfulness-based stress reduction. The
intervention took place in a VR environment, in a winter wonderland setting. Patients were instructed to use Luna at home twice a day (morning and
evening) and when experiencing a hot flash. Participants were asked to use the application for 24 consecutive days. Before and after this 24-day period,
patients completed self-report questionnaires assessing hot flashes, general psychiatric distress, perceived stress, illness perception, sleep quality, and
quality of life.

6. Confidential and Proprietary 6
Virtual reality immersion compared to monitored anesthesia care for hand surgery: A
randomized controlled trial
Clinical study results:
• patients in the VR group received a median of 260 mg less propofol per
case than patients in the usual care control group.
• Despite receiving significantly less propofol sedation, VR group patients
did not have any significant differences compared to usual care group
patients in self-reported assessments.
• VR group patients were discharged from the PACU 22 minutes earlier than
control patients.
• QuickDASH questionnaire assessment of postoperative functional recovery
showed a 20-point difference favoring the VR group.
Methods:
40 adults undergoing hand surgery were randomized to receive either intraoperative VR in addition to Monitored anesthesia care (MAC), or usual
MAC. Patients in both groups received preoperative regional anesthesia at provider discretion. Intraoperatively, the VR group viewed programming of
their choice via a head-mounted display. The primary outcome was intraoperative propofol dose. Secondary outcomes included patient reported pain and
anxiety, overall satisfaction, functional outcome, and post anesthesia care unit (PACU) length of stay.

7. Confidential and Proprietary 7
Lessons Learned – Autism Spectrum Disorder
ASD Overview
• 455 patients (ages 8 and above) enrolled in the last year and a half with Autistic Spectrum Disorder
• Retention of 92%, average of 1 meeting a week, average of 7 months in treatment
• Meeting flow: External Control – Motor, Memory, Mindfulness, Movie story
• 28,400 sessions in VR – mostly motor and cognitive, but also CBT, relaxation, group therapy
• Cast / Mirror capability critical for clinicians and parents
• Most patients are treated both with a psychologist and a PT/OT remotely
Video:
Zack’s
Story
ASD Insights
• Virtual Play Therapy – Helps break the ice, creates interest and engagement, easy access, helps concentrate, energy
discharge
• Proprioception and coordination in VR –dramatic reduction in daily fall incidences
• Immersive stories – help frame conversation on patient, work on five senses, help cope with fears and phobias,
investigate emotions
• Group meetings – 5 patients with 1 clinician, communication skills, eye contact, 360 movies
• Positive side effect – Patients lose weight and get more fit
• Treatment from home – Lowers stress and social anxiety, provides easy access

8. Confidential and Proprietary
Confidential and Proprietary
The future of the Mediverse
• Apple - June 5 & WWDC might be an iPhone moment
• Mixed Reality - New opportunities for Medical use cases, immersive AR
• 5G Networks - Next gen networks and Edge computing to enable Medical XR
• AI and XR - Endless possibilities from content creation to AI clinician
• XRHealth & Amelia Merger - Platform play, healthcare providers need a full solution

9. Confidential and Proprietary 9
Miki Levy
CTO & Co-Founder
miki@xr.health
Thank you!