Mercury poisoning can occur from exposure to elemental, inorganic, and organic mercury. Elemental mercury exposure is usually from inhalation and causes respiratory and neurological symptoms. Inorganic mercury ingestion can cause gastrointestinal and kidney damage. Organic mercury exposure primarily from contaminated seafood causes delayed neurological effects like tremors and ataxia. Diagnosis is made through blood, urine, hair, and clinical exams. Chelation therapy with BAL or DMSA may be used for significant exposures. Public education is important to prevent mercury exposure and proper disposal.
It is heavy metal and bright silvery in appearance.It is liquid and is non poisonous if swallowed. However, it volatilizes at room temp and inhalation of vapors is toxic. It gets widely distributed throughout the body and causes toxic damage to brain, kidney, peripheral nervous system, mucous membranes etc
Brief ideas about the heavy metals and their poisoning. Actual reasons behind their pollution and contamination. Which type of disease occurred by their exposure. Real scenario of the Bangladesh by the contamination and pollution of heavy metals through their exposure
Toxicity is a function of solubility. Insoluble compounds as well as the metallic forms often exhibit negligible toxicity. The toxicity of any metal depends on its ligands. Heavy metal toxicity can result in damaged or reduced mental and central nervous function, lower energy levels, and damage to blood composition, lungs, kidneys, liver, and other vital organs.
Arsenic and many of its compounds are especially potent poisons. Arsenic disrupts ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by competing with phosphate it uncouples oxidative phosphorylation, thus inhibiting energy-linked reduction of NAD+, mitochondrial respiration, and ATP synthesis. Hydrogen peroxide production is also increased, which might form reactive oxygen species and oxidative stress.
These metabolic interferences lead to death from multi-system organ failure
Arsenic poisoning is a medical condition caused by elevated levels of arsenic in the body. The dominant basis of arsenic poisoning is from ground water that naturally contains high concentrations of arsenic. A 2007 study found that over 137 million people in more than 70 countries are probably affected by arsenic poisoning from drinking water
Ecotoxicity & Risk Assessment of Mercury in the Grand Bay National Estuarine Research Reserve:
Profiling Mercury Distribution in the NERR by Cold Vapor Atomic Absorption Spectrometery
It is heavy metal and bright silvery in appearance.It is liquid and is non poisonous if swallowed. However, it volatilizes at room temp and inhalation of vapors is toxic. It gets widely distributed throughout the body and causes toxic damage to brain, kidney, peripheral nervous system, mucous membranes etc
Brief ideas about the heavy metals and their poisoning. Actual reasons behind their pollution and contamination. Which type of disease occurred by their exposure. Real scenario of the Bangladesh by the contamination and pollution of heavy metals through their exposure
Toxicity is a function of solubility. Insoluble compounds as well as the metallic forms often exhibit negligible toxicity. The toxicity of any metal depends on its ligands. Heavy metal toxicity can result in damaged or reduced mental and central nervous function, lower energy levels, and damage to blood composition, lungs, kidneys, liver, and other vital organs.
Arsenic and many of its compounds are especially potent poisons. Arsenic disrupts ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by competing with phosphate it uncouples oxidative phosphorylation, thus inhibiting energy-linked reduction of NAD+, mitochondrial respiration, and ATP synthesis. Hydrogen peroxide production is also increased, which might form reactive oxygen species and oxidative stress.
These metabolic interferences lead to death from multi-system organ failure
Arsenic poisoning is a medical condition caused by elevated levels of arsenic in the body. The dominant basis of arsenic poisoning is from ground water that naturally contains high concentrations of arsenic. A 2007 study found that over 137 million people in more than 70 countries are probably affected by arsenic poisoning from drinking water
Ecotoxicity & Risk Assessment of Mercury in the Grand Bay National Estuarine Research Reserve:
Profiling Mercury Distribution in the NERR by Cold Vapor Atomic Absorption Spectrometery
Biomagnification and Bioaccumulation Lesson PowerPoint, Food Chain, Pollution...www.sciencepowerpoint.com
This PowerPoint Review Game is one very small part of a larger science unit from www.sciencepowerpoint.com. This unit comes with a bundled homework package, detailed lesson notes, worksheets, review games, and much more.
This unit consists of 1000+ slide PowerPoint presentation, assessment, and class notes that are the road map for an exciting and interactive unit full of lab activities, class notes, discussion questions, project ideas, assessments, modified assessment, class notes, PowerPoint Review Games, answer Keys, video links, and much more (Teaching duration = 3+ Weeks) Everything the unit is editable and can be changed to fit any curriculum or time requirement.
Areas of Focus within the Ecology Feeding Levels Unit:
What is Ecology, Concepts in Ecology, Concept-There is no such thing as a free lunch, Energy Comes From the Sun, Food Chains, Trophic Feeding Levels, Producers, Consumers, Decomposers, Aquatic Food Chains, Phytoplankton, Zooplankton, Bioaccumulation, Biomagnification, Animal Dentition and Skull Features, Carnivores, Herbivores, Pyramid of Biomass, Pyramid of Numbers.
Learn more at www.sciencepowerpoint.com
Mercury can be found in many health care devices, including fever thermometers, blood pressure cuffs, and esophageal dilators. It is present in fluorescent lamps. Dental amalgams account for a major contribution to the global mercury load. Mercury is also found in many chemicals and measurement devices used in health care laboratories.
If any of these products are spilled, broken or disposed of improperly, there is a potential for significant harm to human
health and the environment
Presentation on Chemical Hazards in Industry and protection of workers, diagnosis of adverse health effects. Creating their awareness and guidance to Doctors.
Glyphosate research papers - Compiled by Dr.Alex Vasquez and Dr Eva Sirinaths...João Soares
Uma compilação de resumos de artigos científicos sobre os malefícios do glifosato sobre o ambiente, os animais e a saúde pública. Esta compilação foi efectuada pelo Dr. Alex Vasquez e a Dr. Eva Sirinathsinghji, do Instituto de Ciências na Sociedade e contém 245 páginas.
«Glyphosate Research Compilation – Abstracts of studies: Glyphosate’s adverse effects on the environment & on animal & human health - by Dr. Alex Vasquez & Dr. Eva Sirinathsinghji, Institute of Science in Society (245 pages)»
Body Burden of Toxicants - Resources for Healthy Children www.scribd.com/doc/254613619 - For more information, Please see Organic Edible Schoolyards & Gardening with Children www.scribd.com/doc/254613963 - Gardening with Volcanic Rock Dust www.scribd.com/doc/254613846 - Double Food Production from your School Garden with Organic Tech www.scribd.com/doc/254613765 - Free School Gardening Art Posters www.scribd.com/doc/254613694 - Increase Food Production with Companion Planting in your School Garden www.scribd.com/doc/254609890 - Healthy Foods Dramatically Improves Student Academic Success www.scribd.com/doc/254613619 - City Chickens for your Organic School Garden www.scribd.com/doc/254613553 - Huerto Ecológico, Tecnologías Sostenibles, Agricultura Organica www.scribd.com/doc/254613494 - Simple Square Foot Gardening for Schools - Teacher Guide www.scribd.com/doc/254613410 - Free Organic Gardening Publications www.scribd.com/doc/254609890 ~
Unit 8 - Information and Communication Technology (Paper I).pdfThiyagu K
This slides describes the basic concepts of ICT, basics of Email, Emerging Technology and Digital Initiatives in Education. This presentations aligns with the UGC Paper I syllabus.
June 3, 2024 Anti-Semitism Letter Sent to MIT President Kornbluth and MIT Cor...Levi Shapiro
Letter from the Congress of the United States regarding Anti-Semitism sent June 3rd to MIT President Sally Kornbluth, MIT Corp Chair, Mark Gorenberg
Dear Dr. Kornbluth and Mr. Gorenberg,
The US House of Representatives is deeply concerned by ongoing and pervasive acts of antisemitic
harassment and intimidation at the Massachusetts Institute of Technology (MIT). Failing to act decisively to ensure a safe learning environment for all students would be a grave dereliction of your responsibilities as President of MIT and Chair of the MIT Corporation.
This Congress will not stand idly by and allow an environment hostile to Jewish students to persist. The House believes that your institution is in violation of Title VI of the Civil Rights Act, and the inability or
unwillingness to rectify this violation through action requires accountability.
Postsecondary education is a unique opportunity for students to learn and have their ideas and beliefs challenged. However, universities receiving hundreds of millions of federal funds annually have denied
students that opportunity and have been hijacked to become venues for the promotion of terrorism, antisemitic harassment and intimidation, unlawful encampments, and in some cases, assaults and riots.
The House of Representatives will not countenance the use of federal funds to indoctrinate students into hateful, antisemitic, anti-American supporters of terrorism. Investigations into campus antisemitism by the Committee on Education and the Workforce and the Committee on Ways and Means have been expanded into a Congress-wide probe across all relevant jurisdictions to address this national crisis. The undersigned Committees will conduct oversight into the use of federal funds at MIT and its learning environment under authorities granted to each Committee.
• The Committee on Education and the Workforce has been investigating your institution since December 7, 2023. The Committee has broad jurisdiction over postsecondary education, including its compliance with Title VI of the Civil Rights Act, campus safety concerns over disruptions to the learning environment, and the awarding of federal student aid under the Higher Education Act.
• The Committee on Oversight and Accountability is investigating the sources of funding and other support flowing to groups espousing pro-Hamas propaganda and engaged in antisemitic harassment and intimidation of students. The Committee on Oversight and Accountability is the principal oversight committee of the US House of Representatives and has broad authority to investigate “any matter” at “any time” under House Rule X.
• The Committee on Ways and Means has been investigating several universities since November 15, 2023, when the Committee held a hearing entitled From Ivory Towers to Dark Corners: Investigating the Nexus Between Antisemitism, Tax-Exempt Universities, and Terror Financing. The Committee followed the hearing with letters to those institutions on January 10, 202
Palestine last event orientationfvgnh .pptxRaedMohamed3
An EFL lesson about the current events in Palestine. It is intended to be for intermediate students who wish to increase their listening skills through a short lesson in power point.
The French Revolution, which began in 1789, was a period of radical social and political upheaval in France. It marked the decline of absolute monarchies, the rise of secular and democratic republics, and the eventual rise of Napoleon Bonaparte. This revolutionary period is crucial in understanding the transition from feudalism to modernity in Europe.
For more information, visit-www.vavaclasses.com
How to Make a Field invisible in Odoo 17Celine George
It is possible to hide or invisible some fields in odoo. Commonly using “invisible” attribute in the field definition to invisible the fields. This slide will show how to make a field invisible in odoo 17.
Model Attribute Check Company Auto PropertyCeline George
In Odoo, the multi-company feature allows you to manage multiple companies within a single Odoo database instance. Each company can have its own configurations while still sharing common resources such as products, customers, and suppliers.
Read| The latest issue of The Challenger is here! We are thrilled to announce that our school paper has qualified for the NATIONAL SCHOOLS PRESS CONFERENCE (NSPC) 2024. Thank you for your unwavering support and trust. Dive into the stories that made us stand out!
2024.06.01 Introducing a competency framework for languag learning materials ...Sandy Millin
http://sandymillin.wordpress.com/iateflwebinar2024
Published classroom materials form the basis of syllabuses, drive teacher professional development, and have a potentially huge influence on learners, teachers and education systems. All teachers also create their own materials, whether a few sentences on a blackboard, a highly-structured fully-realised online course, or anything in between. Despite this, the knowledge and skills needed to create effective language learning materials are rarely part of teacher training, and are mostly learnt by trial and error.
Knowledge and skills frameworks, generally called competency frameworks, for ELT teachers, trainers and managers have existed for a few years now. However, until I created one for my MA dissertation, there wasn’t one drawing together what we need to know and do to be able to effectively produce language learning materials.
This webinar will introduce you to my framework, highlighting the key competencies I identified from my research. It will also show how anybody involved in language teaching (any language, not just English!), teacher training, managing schools or developing language learning materials can benefit from using the framework.
8. 3 forms of mercury
Organic:
Elemental / inorganic salts organic Hg
Inorganic: Hg + other elements compound or salts
used in industry, cosmetic skin creams
Elemental Hg inorganic Hg in the body
Elemental: quick silver, thermometer, fluorescent light
bulb, electrical switch, dental amalgam
Microorganism in water/ soil
9. How people are exposed to Hg ?
Elemental Hg: breath elemental Hg vapors (dental
office, smelting operation, Hg spilled or released )
Inorganic Hg: Hg salts are used
Organic Hg: seafood consumption (fish, shellfish
contaminated with methylmercury), pass through
the placenta , breast milk
13. Pathophysiology
Binding to sulfur
Replacing hydrogen ion in sulfhydryl groups
React with phosphoryl, carboxyl and amide group
widespread enzymes dysfunction
14. Pathophysiology
Mercury salt poisoning: necrosis of GI mucosa and
proximal renal tubules (shortly after exposure)
Mercurial ointments use: membranous
glomerulonephritis, acrodynia
Methyl mercury poisoning:
– fetal Minamata disease: atrophy of the cerebellar
hemispheres, postcentral gyri, calcarine area ataxia,
sensory neuropathy, visual field constriction
– Less severe in adult
16. Elemental mercury
Common in occupational setting
Max. limit of ambient air concentration 0.9
mg/m3 (0.1 mg/m3)
Children is more sensitive to mercury vapor:
minute ventilation to body size
Direct aspiration of metallic mercury: massive
endotracheal hemorrhage
Vacuuming spilled mercury
18. Amalgam (elemental Hg)
"Amalgam is not a true alloy. It is made up of 50% mercury, which is not locked
into a set filling but escapes continuously during the entire life of the filling in the
form of vapor, ions and abraded particles“
Australasian Society Of Medicine And Toxicology
19. Amalgam: advantages vs disadvantages
Patient
Durable and cheap
Low rate of local side effect
No conclusive evidence for
systemic adverse effect
Environmental & health care
provider
Decreased exposure due to
good conduct and Hg
hygiene protocols
Environmental impact of
dental amalgam is almost
insignificant
J Ir Dent Assoc. 2013 Dec-2014 Jan;59(6):311-7.
20. Inorganic mercury
Ingestion: caustic gastroenteritis, grayish
discoloration of mucous membrane, metallic taste
Renal: oliguria (within 3 days) from proximal
tubular necrosis
No report of Hg poisoning form button battery
ingestion
Pediatrics. 1992;89:747–757
23. Thimerosal (inorganic Hg)
0.1% thimerosal or 600 mcg/mL Hg
A preservative in multi-dose vials in areas with in
adequate refrigeration
No longer use in the US for routine childhood
vaccines since 2001
Global Alliance for Vaccines and Immunisation.Report to the GAVI Alliance Board Report of the Chief Executive Officer. 2012.
Immunol Allergy Clin North Am.2003;23:589–603.
24. Organic Hg compound
Almost purely permanent neurologic disease
Associated with methylmercury
Lipophilic property
Delayed neurotoxicity (weeks to months)
Detected in breast milk (30% of blood conc.)
25. Source and route of organic Hg exposure
Seafood
FDA limit: 1 ppm for methyl mercury in fish
EPA limit: 0.1 mcg/kg/day
High blood concentration group in self-reported
high consumers of seafood
High risk groups:
– pregnant women or who may become pregnant
– nursing mother
– young children
26. Minamata
Decreased wt. and muscle tone
Profound developmental delay
Seizure
Deafness and blindness
Severe spasticity
28. Diagnostic testing for Mercury
Whole Blood 24-hour Urine Hair Clinical
Elemental/Inorganic (+) (++) (+) (+)
Acute, transient Confirm exposure Reflects past
exposure and
external adsorption
Poor correlation to
total body burden
(TBB)
Monitor chelation Early detection
Poor correlation to
TBB
Organic (++) (–) (+) (+)
Best reflects TBB
(N-acetyl-β-D-
glucosaminidase, β2-
microglobulin)
Fecal elimination Reflects past
exposure and
external adsorption
Poor correlation to
TBB
Reflects irreversible
CNS toxicity
Early detection
29. Hg concentration
Overlap of Hg concentration found in the normal
population, asymptomatic exposed individuals
No correlation between either whole blood or
urine mercury concentration and mercury toxicity
1.0 μg/L or less for whole blood and 0.5 μg/L for
urine are generally considered to exposure in
non-poisoned individuals
Centers for Disease Control and Prevention. Fourth National Report on Human Exposure to Environmental
Chemicals. July 26, 2012. 2009.
30. General management for elemental Hg
Aspiration: postural drainage, ETT suction
Localized injection: surgical excision
Sweep spilled Hg into tightly sealed container
No vacuum for spilled Hg
Broken CFL bulb: EPA guideline / local
requirements
www.pcd.go.th/info_serv/haz_lamp.htm
Opening window to release vapor
Adhesive tape to pick up fragments
31. General management for inorganic Hg
Activated charcoal (AC): substantial adsorption
(800 mcg mercuric chloride: 1 g AC)
Whole bowl irrigation with PEG
Severe gastroenteritis
– Removal over endoscopic evaluation in suspected
penetrating GI mucosal injury
32. General management for organic Hg
Chronic ingestion of contaminated food
Aggressive decontamination: acute ingestion,
dermal exposure
33. Chelation (BAL, DMSA)
Thiol groups in chelators compete with
endogenous sulfhydryl groups for the binding of
mercury
Preventing inactivation of sulfhydryl-containing
enzymes and other essential proteins
Indication:
– history of significant mercury exposure with
– Presence of typical symptoms of mercury poisoning
Urine or blood concentration: unclear cases,
guide the duration of therapy
34. Summary
3 major forms: elemental, inorganic and organic
Large variety of clinical presentation
Neurologic sequelae esp. from organic Hg
exposures : largely irreversible
Promotion of public education and awareness
regarding
– Danger of Hg
– Avoidance
– Proper disposal
Editor's Notes
Neurasthenia is a symptom complex that includes fatigue, depression, headaches, hypersensitivity to stimuli, psychosomatic complaints, weakness, and loss of concentrating ability
Erethism, derived from the Greek word red, describes the easy blushing and extreme shyness of affected individuals.
acrodynia, or “pink disease,” which is an erythematous, edematous, and hyperkeratotic induration of the palms, soles, and face, and a pink papular rash that was first described in a subset of children exposed to mercurous chloride powders.98