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Class - 11
Why cell Divided ?
• Every organism start their life from a single cell.
• Growth and reproduction are characteristics of cells.
• Every organism repair their body by cell division.
Amitosis
Mitosis
Meiosis
The sequence of events by which a cell duplicates its genome,
synthesizes the other constituents of the cell and eventually
divides into two daughter cells is termed cell cycle.
Phases of Cell Cycle
Mitosis phase Interphase
karyokinesis cytokinesis
G1 phase
G2 phase
S phase
Prophase
Metaphase
Anaphase
Telophase
Daughter Cell
Mature Cell
During the S or synthesis phase DNA synthesis or
replication takes place. In this time the amount of DNA
per cell doubles However, there is no increase in the
chromosome number;
During the G2 phase, proteins are synthesised in
preparation for mitosis while cell growthcontinues.
Karyokinesi
s
Prophase
(1)Chromosomal material
condenses to form compact
mitotic chromosomes.
Chromosomes are seen to be
composed of two chromatids
attached together at the
centromere.
(2) Chromosomes hold spindle
fibre
(3) Nucleolus membrane
Become Disappear
Metaphase -
(1) Spindle fibers attach to kinetochores of chromosomes.
(2) Chromosomes are moved to spindle equator.
(3) Chromatids arms are toward pole.
Anaphase -
(1) Centromeres split and chromatids separate.
(2) Chromatids move to opposite poles
Telophase -
(1) Chromosomes cluster
at opposite spindle poles
and their identity is lost
as discrete elements.
(2) Nuclear membrane
assembles around the
chromosome clusters.
(3) Nucleolus, Golgi
complex and ER reform
Cytokinesis -
(1) After the division of nucleolus cell divided into two daughter cell.
(2) At the time of cytoplasmic division, organelles like mitochondria
and plastids get distributed between the two daughter cells
 The growth of multicellular organisms is due to
mitosis.
 A very significant contribution of mitosis is cell repair.
 The cells of the upper layer of the epidermis, cells of
the lining of the gut, and blood cells are being
constantly replaced.
 Mitotic divisions in the meristematic tissues – the
apical and the lateral cambium, result in a continuous
growth of plants throughout their life
• Meiosis involves two sequential cycles of nuclear and
cell division called meiosis I and meiosis II but only a
single cycle of DNA replication.
• Meiosis I is initiated after the parental chromosomes
have replicated to produce identical sister chromatids at
the S phase.
• Meiosis involves pairing of homologous chromosomes
and recombination between them.
• Four haploid cells are formed at the end of meiosis II.
Meiosis-I
Prophase I: Prophase of the first meiotic division is typically
longer and more complex when compared to prophase of
mitosis. It has been further subdivided into the following
five phases based on chromosomal behavior.
• Leptotene,
• Zygotene,
• Pachytene,
• Diplotene
• Diakinesis
Leptotene - During leptotene stage the chromosomes
become thick and gradually visible under the light
microscope.
Zygotene - During this stage chromosomes start pairing
together and this process of association is called
synapsis. Such paired chromosomes are called
homologous chromosomes
Pachytene- During this stage bivalent chromosomes now
clearly appears as tetrads. This stage is characterized by the
appearance of recombination nodules, the sites at which
crossing over occurs between non-sister chromatids of the
homologous chromosomes. Crossing over is the exchange of
genetic material between two homologous chromosomes
Diplotene - The beginning of diplotene is recognised by the
dissolution of the synaptonemal complex and the tendency of
the recombined homologous chromosomes of the bivalents to
separate from each other except at the sites of crossovers.
These X-shaped structures, are called chiasmata
Diakinesis - Repulsion process start in the homologous
chromosomes. Chromosomes become seprate. By the end of
diakinesis, the nucleolus disappears and the nuclear envelope
also breaks down. Diakinesis represents transition to
metaphase.
Metaphase I: The bivalent chromosomes align on the
equatorial plate. The microtubules from the opposite poles of
the spindle attach to the pair of homologous chromosomes
Anaphase I: The homologous chromosomes separate, while
sister chromatids remain associated at their centromeres.
Telophase I -
(1) Chromosomes cluster at opposite spindle poles and their identity is lost
as discrete elements.
(2) Nuclear membrane assembles around the chromosome clusters.
Meiosis II - Meiosis second division is same as mitosis division. It is also
completed in the following stages, Prophase II, Metaphase II, Anaphase II,
and Telophase II at the end of meiosis division four haploid daughter cell
obtained.
1. Meiosis form gametes that are required for sexual reproduction
2. Meiosis maintains the fixed number of chromosomes in
sexually reproducing organisms by having the same during
gametogenesis
3. In meiosis, paternal and maternal chromosomes assort
independently.
4. Meiosis introduces a new combination of traits or variations.
5. Chromosomal and genomic mutations occur by irregularities of
meiotic division. Some of these mutations are useful to the
organism.
P.N. Patidar -

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Cell cycle and division

  • 2. Why cell Divided ? • Every organism start their life from a single cell. • Growth and reproduction are characteristics of cells. • Every organism repair their body by cell division.
  • 6. The sequence of events by which a cell duplicates its genome, synthesizes the other constituents of the cell and eventually divides into two daughter cells is termed cell cycle.
  • 7.
  • 8. Phases of Cell Cycle Mitosis phase Interphase karyokinesis cytokinesis G1 phase G2 phase S phase Prophase Metaphase Anaphase Telophase
  • 10. During the S or synthesis phase DNA synthesis or replication takes place. In this time the amount of DNA per cell doubles However, there is no increase in the chromosome number;
  • 11. During the G2 phase, proteins are synthesised in preparation for mitosis while cell growthcontinues.
  • 12. Karyokinesi s Prophase (1)Chromosomal material condenses to form compact mitotic chromosomes. Chromosomes are seen to be composed of two chromatids attached together at the centromere. (2) Chromosomes hold spindle fibre (3) Nucleolus membrane Become Disappear
  • 13. Metaphase - (1) Spindle fibers attach to kinetochores of chromosomes. (2) Chromosomes are moved to spindle equator. (3) Chromatids arms are toward pole.
  • 14. Anaphase - (1) Centromeres split and chromatids separate. (2) Chromatids move to opposite poles
  • 15. Telophase - (1) Chromosomes cluster at opposite spindle poles and their identity is lost as discrete elements. (2) Nuclear membrane assembles around the chromosome clusters. (3) Nucleolus, Golgi complex and ER reform
  • 16. Cytokinesis - (1) After the division of nucleolus cell divided into two daughter cell. (2) At the time of cytoplasmic division, organelles like mitochondria and plastids get distributed between the two daughter cells
  • 17.
  • 18.  The growth of multicellular organisms is due to mitosis.  A very significant contribution of mitosis is cell repair.  The cells of the upper layer of the epidermis, cells of the lining of the gut, and blood cells are being constantly replaced.  Mitotic divisions in the meristematic tissues – the apical and the lateral cambium, result in a continuous growth of plants throughout their life
  • 19. • Meiosis involves two sequential cycles of nuclear and cell division called meiosis I and meiosis II but only a single cycle of DNA replication. • Meiosis I is initiated after the parental chromosomes have replicated to produce identical sister chromatids at the S phase. • Meiosis involves pairing of homologous chromosomes and recombination between them. • Four haploid cells are formed at the end of meiosis II.
  • 20. Meiosis-I Prophase I: Prophase of the first meiotic division is typically longer and more complex when compared to prophase of mitosis. It has been further subdivided into the following five phases based on chromosomal behavior. • Leptotene, • Zygotene, • Pachytene, • Diplotene • Diakinesis
  • 21. Leptotene - During leptotene stage the chromosomes become thick and gradually visible under the light microscope.
  • 22. Zygotene - During this stage chromosomes start pairing together and this process of association is called synapsis. Such paired chromosomes are called homologous chromosomes
  • 23. Pachytene- During this stage bivalent chromosomes now clearly appears as tetrads. This stage is characterized by the appearance of recombination nodules, the sites at which crossing over occurs between non-sister chromatids of the homologous chromosomes. Crossing over is the exchange of genetic material between two homologous chromosomes
  • 24. Diplotene - The beginning of diplotene is recognised by the dissolution of the synaptonemal complex and the tendency of the recombined homologous chromosomes of the bivalents to separate from each other except at the sites of crossovers. These X-shaped structures, are called chiasmata
  • 25. Diakinesis - Repulsion process start in the homologous chromosomes. Chromosomes become seprate. By the end of diakinesis, the nucleolus disappears and the nuclear envelope also breaks down. Diakinesis represents transition to metaphase.
  • 26. Metaphase I: The bivalent chromosomes align on the equatorial plate. The microtubules from the opposite poles of the spindle attach to the pair of homologous chromosomes
  • 27. Anaphase I: The homologous chromosomes separate, while sister chromatids remain associated at their centromeres.
  • 28. Telophase I - (1) Chromosomes cluster at opposite spindle poles and their identity is lost as discrete elements. (2) Nuclear membrane assembles around the chromosome clusters.
  • 29. Meiosis II - Meiosis second division is same as mitosis division. It is also completed in the following stages, Prophase II, Metaphase II, Anaphase II, and Telophase II at the end of meiosis division four haploid daughter cell obtained.
  • 30. 1. Meiosis form gametes that are required for sexual reproduction 2. Meiosis maintains the fixed number of chromosomes in sexually reproducing organisms by having the same during gametogenesis 3. In meiosis, paternal and maternal chromosomes assort independently. 4. Meiosis introduces a new combination of traits or variations. 5. Chromosomal and genomic mutations occur by irregularities of meiotic division. Some of these mutations are useful to the organism.