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Medical Equipment II
X-ray Imaging
Inas A. Yassine
Associate Professor,
Systems and Biomedical Engineering Department,
Faculty of Engineering - Cairo University
iyassine@eng.cu.edu.eg
Course Content
§ Imaging
§ X-Ray Imaging
§ Computer Tomography (CT)
§ Nuclear Medicine
§ Positron Emission Tomography (PET)
§ Single Positron Emission Computer Tomography (SPECT)
§ Radiotherapy
§ X-ray
§ LINear ACcelerator (LINAC)
§ Cobalt
Machine Learning Spring 2014 Inas A.Yassine 2
Student Evaluation and grading
§ 30% Class work
§ Midterm
§ Study Report
§ Homeworks
§ 70% Term Exam
Machine Learning Spring 2014 Inas A.Yassine 3
Reference Books:
§ Russell K. Hobbie, Bradley J. Roth "Intermediate
Physics and Biology (Chapter 14, 15), Springer,
2007."
§ N. Smith et.Al., "Introduction to Medical Imaging
Physics, Engineering and Clinical Applications“.
2011.
§ P. Mayles et.al.,"Handbook of Radiotherapy
Physics:Theory and Practice", 2007.
Introduction to Atoms and Light
Medical equipment Spring 2015 Inas A.Yassine 5
Nature of light
§ Light travels in a vacuum with a velocity c = 3
×108 m/s
§ When light travels through matter, its speed is less
than this and is given by
n is index of refraction of substance
§ depends on both the composition of substance
and color of light
n
c
cn =
Nature of light
§ A traveling wave of light can be described by f(x −
cnt)
represents a disturbance traveling along the x axis in the
positive direction
§ If wave is sinusoidal, then the period ,T,
frequency,γ , and wavelength, λ, are related by
ln== C
T
c ,
1
Nature of light
§ As light moves from one medium into
another where it travels with a different
speed, frequency remains the same.
§ Wavelength changes as the speed changes.
§ Each particle of light or photon has energy
E given by:
Nature of light
Atomic Energy
§ Energy level: isolated atoms have specific
discrete internal energies
§ An atom can change from one energy level
to another by emitting or absorbing a
photon with an energy equal to the energy
difference between the levels
Atomic Energy Levels
§ Let the energy levels be labeled the energy of the
ith state being Ei.
§ The lowest possible internal energy for each atom
when the atom is in this state, no further energy
loss can take place.
§ If Ei is greater than the lowest energy, then the
atom can lose energy by emitting a photon of
energy Ei −Ef and exist in a lower
energy state Ef
Atomic energy Levels
§ Ionization energy is the smallest amount of energy
required to remove an electron from the atom when the
atom is in its ground state.
Radiation
Ionizing
Non-
Ionizing
Direct Indirect §Microwaves
§Radiofrequency
§Ultrasound
§Infrared
Atomic Energy Level
§ An atom
§ can receive energy from an external source, such as
a collision with another atom or some other
particle.
§ Can absorb a photon of the proper energy.
§ Allows one of its electrons to move to a higher
energy level, as long as that level is not already
occupied.
§ Can get rid of excess energy by emitting a photon
Atomic Energy levels
§ Energy levels given as
Scattering and Absorption of
Radiation
§ Photons in a vacuum travel in a straight line.
§ When they travel through matter
§ are apparently slowed down (n>1)
§ May be scattered or absorbed
§ Visible light does not pass through walls
§ The beam shape is fanning near by the source.
§ At a distant source of photons that travel in straight lines, to
form a nearly parallel beam of photons
Photon Interaction with matter
§ Passing through
§ Scattering
§ Absorption
Photon Interaction with matter
§ Assume N photons passing through a thin layer of
material dz
§ μ is the total linear attenuation coefficient.
§ μs and μa are linear scattering and absorption
coefficients
Imaging tool Full Definition
§ Effect produced
§ Interaction with the body
§ Effect to be Detected
§ Image Construction
X-Rays Imaging
Machine Learning Spring 2014 Inas A.
Yassine 19
X-ray Imaging
§ The tube – X-rays are produced
§ The body – X-rays interact with the body
§ The image – X-rays interact with film,
Detectors
§ Film processing, Signal analysis
Diagnostic and Therapeutic X-Ray
§ Diagnostic radiology
§ uses low energy X rays for imaging
§ No Tissue Damage Reversible
§ Effect Detection
§ Max Dose calculation
§ Radiotherapy
§ uses high energy X rays to treat tumor.
§ ionizes the water in the cell and induces formation of free
radicals which can damage of genetic material (DNA).
§ Normal cells are also affected adversely by radiation but have
the capacity of repair. reversible.
X-rays
§ Made of photons
§ Travel at speed of light
§ Travels in a straight line
§ Has no mass nor charge (cannot be focused by
magnets)
§ X-ray beam has a mix of energies
§ Diagnostic X-ray range 20-150 kVp
The X-ray tube
X-ray tube
X-ray production
§ Push the “rotor” or
“prep” button
§ Charges the filament –
causes thermionic
emission (e- cloud)
§ Begins rotating the
anode.
§ Push the “exposure” or
“x-ray” button
§ e-’s move toward anode
target to produce x-rays
Coverage Calculation
𝑓 = 𝐹𝑠𝑖𝑛	𝜃
where 𝜃 is the bevel angle and F the width of
the electron beam
𝐶𝑜𝑣𝑒𝑟𝑎𝑔𝑒
= 	2 𝑠𝑜𝑢𝑟𝑐𝑒 − 𝑝𝑎𝑡𝑖𝑒𝑛𝑡	 𝐷𝑖𝑠𝑡𝑎𝑛𝑐𝑒 ∗ 𝑡𝑎𝑛 𝜃
Coverage
Anode Heel Effect
Energy Spectrum of X-ray
Exposure Factors:
§ kVp – kilovoltage peak
§ mA – miliamps (current)
§ s – seconds (duration of exposure)
§ mAs – product of mA and s
Exposure factors are set by
radiographer

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Medical Equipment presentation 1 2

  • 1. Medical Equipment II X-ray Imaging Inas A. Yassine Associate Professor, Systems and Biomedical Engineering Department, Faculty of Engineering - Cairo University iyassine@eng.cu.edu.eg
  • 2. Course Content § Imaging § X-Ray Imaging § Computer Tomography (CT) § Nuclear Medicine § Positron Emission Tomography (PET) § Single Positron Emission Computer Tomography (SPECT) § Radiotherapy § X-ray § LINear ACcelerator (LINAC) § Cobalt Machine Learning Spring 2014 Inas A.Yassine 2
  • 3. Student Evaluation and grading § 30% Class work § Midterm § Study Report § Homeworks § 70% Term Exam Machine Learning Spring 2014 Inas A.Yassine 3
  • 4. Reference Books: § Russell K. Hobbie, Bradley J. Roth "Intermediate Physics and Biology (Chapter 14, 15), Springer, 2007." § N. Smith et.Al., "Introduction to Medical Imaging Physics, Engineering and Clinical Applications“. 2011. § P. Mayles et.al.,"Handbook of Radiotherapy Physics:Theory and Practice", 2007.
  • 5. Introduction to Atoms and Light Medical equipment Spring 2015 Inas A.Yassine 5
  • 6. Nature of light § Light travels in a vacuum with a velocity c = 3 ×108 m/s § When light travels through matter, its speed is less than this and is given by n is index of refraction of substance § depends on both the composition of substance and color of light n c cn =
  • 7. Nature of light § A traveling wave of light can be described by f(x − cnt) represents a disturbance traveling along the x axis in the positive direction § If wave is sinusoidal, then the period ,T, frequency,γ , and wavelength, λ, are related by ln== C T c , 1
  • 8. Nature of light § As light moves from one medium into another where it travels with a different speed, frequency remains the same. § Wavelength changes as the speed changes. § Each particle of light or photon has energy E given by:
  • 10. Atomic Energy § Energy level: isolated atoms have specific discrete internal energies § An atom can change from one energy level to another by emitting or absorbing a photon with an energy equal to the energy difference between the levels
  • 11. Atomic Energy Levels § Let the energy levels be labeled the energy of the ith state being Ei. § The lowest possible internal energy for each atom when the atom is in this state, no further energy loss can take place. § If Ei is greater than the lowest energy, then the atom can lose energy by emitting a photon of energy Ei −Ef and exist in a lower energy state Ef
  • 12. Atomic energy Levels § Ionization energy is the smallest amount of energy required to remove an electron from the atom when the atom is in its ground state. Radiation Ionizing Non- Ionizing Direct Indirect §Microwaves §Radiofrequency §Ultrasound §Infrared
  • 13. Atomic Energy Level § An atom § can receive energy from an external source, such as a collision with another atom or some other particle. § Can absorb a photon of the proper energy. § Allows one of its electrons to move to a higher energy level, as long as that level is not already occupied. § Can get rid of excess energy by emitting a photon
  • 14. Atomic Energy levels § Energy levels given as
  • 15. Scattering and Absorption of Radiation § Photons in a vacuum travel in a straight line. § When they travel through matter § are apparently slowed down (n>1) § May be scattered or absorbed § Visible light does not pass through walls § The beam shape is fanning near by the source. § At a distant source of photons that travel in straight lines, to form a nearly parallel beam of photons
  • 16. Photon Interaction with matter § Passing through § Scattering § Absorption
  • 17. Photon Interaction with matter § Assume N photons passing through a thin layer of material dz § μ is the total linear attenuation coefficient. § μs and μa are linear scattering and absorption coefficients
  • 18. Imaging tool Full Definition § Effect produced § Interaction with the body § Effect to be Detected § Image Construction
  • 19. X-Rays Imaging Machine Learning Spring 2014 Inas A. Yassine 19
  • 20. X-ray Imaging § The tube – X-rays are produced § The body – X-rays interact with the body § The image – X-rays interact with film, Detectors § Film processing, Signal analysis
  • 21. Diagnostic and Therapeutic X-Ray § Diagnostic radiology § uses low energy X rays for imaging § No Tissue Damage Reversible § Effect Detection § Max Dose calculation § Radiotherapy § uses high energy X rays to treat tumor. § ionizes the water in the cell and induces formation of free radicals which can damage of genetic material (DNA). § Normal cells are also affected adversely by radiation but have the capacity of repair. reversible.
  • 22. X-rays § Made of photons § Travel at speed of light § Travels in a straight line § Has no mass nor charge (cannot be focused by magnets) § X-ray beam has a mix of energies § Diagnostic X-ray range 20-150 kVp
  • 25. X-ray production § Push the “rotor” or “prep” button § Charges the filament – causes thermionic emission (e- cloud) § Begins rotating the anode. § Push the “exposure” or “x-ray” button § e-’s move toward anode target to produce x-rays
  • 26. Coverage Calculation 𝑓 = 𝐹𝑠𝑖𝑛 𝜃 where 𝜃 is the bevel angle and F the width of the electron beam 𝐶𝑜𝑣𝑒𝑟𝑎𝑔𝑒 = 2 𝑠𝑜𝑢𝑟𝑐𝑒 − 𝑝𝑎𝑡𝑖𝑒𝑛𝑡 𝐷𝑖𝑠𝑡𝑎𝑛𝑐𝑒 ∗ 𝑡𝑎𝑛 𝜃
  • 30. Exposure Factors: § kVp – kilovoltage peak § mA – miliamps (current) § s – seconds (duration of exposure) § mAs – product of mA and s Exposure factors are set by radiographer