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measures of central tendency biostastistics
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NANOSPHERES : NANOCRYSTALS : NANOCAPSULES
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PROTEINS POLYSACCHARIDES Gelatin Albumin Lectins Legumin Vicilin Alginate Dextran Chitosan Agarose Pullulan
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PRE-POLYMERIZED (1ST GROUP) POLYMERIZED IN PROCESS (2ND
GROUP) Poly (ε-caprolactone) (PECL) Poly lactic acid (PLA) Poly (lactide-co-glycolide) (PLGA) Polystyrene Poly (isobutylcyanoacrylates) (PICA) Poly (butylcyanoacrylates) (PBCA) Poly hexylcyanoacrylate (PHCA) Poly methyl (methacrylate) (PMMA) Copolymer of amino alkyl methacrylate methyl methacrylate
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POLYMER USED TECHNIQUE
CANDIDATE DRUG Hydrophilic Albumin, gelatin Alginate, Chitosan Dextran Hydrophobic Polyalkylcyanoacrylates Polyesters PLA, PLGA, PECL Heat denaturation & cross- linking in W/O emulsion Desolvation & cross-linking in aqueous medium Cross-linking in aqueous medium Polymer precipitation in organic solvent Emulsion polymerization Interfacial O/W polymerization Solvent extraction – evaporation Solvent displacement Salting out Hydrophilic Hydrophilic & Protein affinity Hydrophilic & Protein affinity Hydrophilic Hydrophilic Hydrophobic Hydrophilic & Hydrophobic Soluble in polar solvent
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Nanocapsules
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