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VITAMINS
PREPERAR BY
DIPANJAL BORAH
CHAIDUAR COLLEGE
MLT DEPARTMENT
 retinol, retinal, retinoic acid
 two form retinal and β-carotin
 deficiency cause- night blindness, dry skin
 source- liver, egg
 rods and cons are vitamin A dependent
 Ascorbic acid
 Oxidation- reduction reaction
 collagen formation
 bone formation
 help in iron absorption in stomach
 tryptophan metabolism, Folic acid metabolism
 help in synthesis of corticosteroid hormone
 It has immunological function
 deficiency- Scurvy, loose teeth
Source- Amla, limon, Gerrn vigitable
 two types- 1) Argostrol, 2) 7-dehydroxycholestrol
 7-dehydrocholestrol cholecalciferol
 cholecalciferol vitamin D
 Increase intestinal absorption of calcium & phosphate
 minarilization of bone
 deficiency- rickets
 source- fatty fish, fish liver
 normal name- tocopherol
 natural antioxident
 essential for reproduction
 anti sterility vitamin
Necessary for membrane structure
 proper storage of creatinine in muscle
 Absorbe in small intestine along with fat
 deficiency- Sterility, degenerative change in muscle
 Source- vegetable oil, cotton seed oil, meat
 It has coenzyme function & Fat soluble vitamin
 required for production of blood clotting factor
 3 from of Vitamin K phyloquinanne, menaquinane,
menadiane
 The Factor 2,7,9 and 10 are synthesis in liver in the
help of vitamin K
 General name- Thiamin
 thiamin is a cofactor in dehydrogenises reaction
(removing Co2 and add CoA)
 conversion of pyruvate to (lactate , Acetyle Coa etc).
Thiamin is necessary
 deficiancy- beri beri, warnicke-korsakoff syndrome
 source- brown rice, wheat, liver, egg etc
 General name- Riboflavin
 absorbed in dudanum
 FMN & FAD are co-enzyme in some reaction
 deficiancy- glosssitis, dermotitis
Source- milk and milk product
General name- Niacin, nicotonic acid
 act as a co-enzyme NAD+ & NADP+
 pallagra preventive factor
 60 mg tryptophan= 1mg of niacin
 deficiancy- dermotitis, diarrhea & dementia
Souce- liver, meat
 general name- panthothanic acid
 act as a CoA as acetyle CoA, succnyle CoA
It start TCA cycle, ketogenesis, ketolysis, fatty acid
synthesis
 general name- pyrodoxine, pyrodoxal, pyrodoxamine
 pyrodoxal phosphate presipited the reaction like
transamination and decarboxylation.
PLP convert amino acid to keto acid keto acid get entert
to TCA cycle and produce energy.
 deficiency- neurological symptome, depresion mantel
confusion
 source- Egg yolk, Fish, milk
General name- Biotin
 act as a carrear of Co2 in carboxilation reaction
Pyruvate to oxaloacetet is biotin dependent
Necessary in fatty acid synthesis
 Acetyl CoA (bi) malonyl CoA
Propional CoA (bi) methylmalonyl CoA
 deficiancy- glositis, dermotitis, anaemia
 source- liver, milk, tomato
 general name- Folic acid (folate)
 first conjugate in dudenum & absorbed
 It involve in one carbon metabolism
 coenzyme is tetrahydrofolate(THF)
 deficiancy- impaired DNA synthesis and macrocytic
RBC
 source- green vegetable, Liver, meat etc
 general name- cobalamin, cynacobalamin,
methylcobalamin
 first it bind with intrensic factor in stomach then
absorbed
 vitamin B12 and folic acid together make metel group
Required in DNA synthesis
 deficiancy- megaloblastic anaemia, low Hb, MCV is
increase.
THANKYOU

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vitamins.pptx

  • 2.  retinol, retinal, retinoic acid  two form retinal and β-carotin  deficiency cause- night blindness, dry skin  source- liver, egg  rods and cons are vitamin A dependent
  • 3.  Ascorbic acid  Oxidation- reduction reaction  collagen formation  bone formation  help in iron absorption in stomach  tryptophan metabolism, Folic acid metabolism  help in synthesis of corticosteroid hormone  It has immunological function  deficiency- Scurvy, loose teeth Source- Amla, limon, Gerrn vigitable
  • 4.  two types- 1) Argostrol, 2) 7-dehydroxycholestrol  7-dehydrocholestrol cholecalciferol  cholecalciferol vitamin D  Increase intestinal absorption of calcium & phosphate  minarilization of bone  deficiency- rickets  source- fatty fish, fish liver
  • 5.  normal name- tocopherol  natural antioxident  essential for reproduction  anti sterility vitamin Necessary for membrane structure  proper storage of creatinine in muscle  Absorbe in small intestine along with fat  deficiency- Sterility, degenerative change in muscle  Source- vegetable oil, cotton seed oil, meat
  • 6.  It has coenzyme function & Fat soluble vitamin  required for production of blood clotting factor  3 from of Vitamin K phyloquinanne, menaquinane, menadiane  The Factor 2,7,9 and 10 are synthesis in liver in the help of vitamin K
  • 7.  General name- Thiamin  thiamin is a cofactor in dehydrogenises reaction (removing Co2 and add CoA)  conversion of pyruvate to (lactate , Acetyle Coa etc). Thiamin is necessary  deficiancy- beri beri, warnicke-korsakoff syndrome  source- brown rice, wheat, liver, egg etc
  • 8.  General name- Riboflavin  absorbed in dudanum  FMN & FAD are co-enzyme in some reaction  deficiancy- glosssitis, dermotitis Source- milk and milk product
  • 9. General name- Niacin, nicotonic acid  act as a co-enzyme NAD+ & NADP+  pallagra preventive factor  60 mg tryptophan= 1mg of niacin  deficiancy- dermotitis, diarrhea & dementia Souce- liver, meat
  • 10.  general name- panthothanic acid  act as a CoA as acetyle CoA, succnyle CoA It start TCA cycle, ketogenesis, ketolysis, fatty acid synthesis
  • 11.  general name- pyrodoxine, pyrodoxal, pyrodoxamine  pyrodoxal phosphate presipited the reaction like transamination and decarboxylation. PLP convert amino acid to keto acid keto acid get entert to TCA cycle and produce energy.  deficiency- neurological symptome, depresion mantel confusion  source- Egg yolk, Fish, milk
  • 12. General name- Biotin  act as a carrear of Co2 in carboxilation reaction Pyruvate to oxaloacetet is biotin dependent Necessary in fatty acid synthesis  Acetyl CoA (bi) malonyl CoA Propional CoA (bi) methylmalonyl CoA  deficiancy- glositis, dermotitis, anaemia  source- liver, milk, tomato
  • 13.  general name- Folic acid (folate)  first conjugate in dudenum & absorbed  It involve in one carbon metabolism  coenzyme is tetrahydrofolate(THF)  deficiancy- impaired DNA synthesis and macrocytic RBC  source- green vegetable, Liver, meat etc
  • 14.  general name- cobalamin, cynacobalamin, methylcobalamin  first it bind with intrensic factor in stomach then absorbed  vitamin B12 and folic acid together make metel group Required in DNA synthesis  deficiancy- megaloblastic anaemia, low Hb, MCV is increase.