Water is our most essential resource for life, the economy, and has no substitute. However, water demand is increasing with population growth while supply remains fixed. As water becomes scarcer, political conflicts are likely to emerge. Currently, many people live without access to clean water and infrastructure in the US and elsewhere is failing. Climate change will exacerbate water challenges. By 2050, half the world's population may face water stress. Solutions include conservation, reuse, technology advances, and better management of water as a valued resource rather than a right. Water prices will need to rise to reflect its true cost and value to shape sustainable use.