Mannitol is a non-electrolyte diuretic used to promote diuresis, prevent and treat oliguric acute renal failure, reduce elevated intraocular and intracranial pressure, promote toxic substance excretion, and as a therapeutic measure in cystic fibrosis and asthma tests in children. It has a half-life of 45-100 minutes and onset of action ranges from 15-30 minutes for ICP reduction to 1-3 hours for diuresis. Dosages vary from 50-200g per 24 hours in geriatrics to 1-5g/kg in pediatric patients depending on the condition being treated. Mannitol has many drug interactions and adverse effects that require monitoring like hypersensitivity