This document provides an overview of HIV and AIDS. It discusses the background of HIV, including how it attacks the immune system. It describes the stages of HIV infection and provides a brief history of AIDS. The epidemiological triad of agent, host, and environment related to HIV transmission is examined. At-risk groups and behaviors are identified. Global and national statistics on prevalence and distribution are presented. Objectives of preventing and controlling HIV/AIDS through various strategies like education, testing, and treatment are outlined. Key findings around transmission modes, clinical features, and prevention/management approaches are summarized.
Presentation made by Zsuzsanna Jakab, WHO Regional Director for Europe, at the meeting "Health in Action reforming the Greek National Health System to Improve Citizens’ Health", on 5 March 2014, Athens, Greece.
Presentation made by Zsuzsanna Jakab, WHO Regional Director for Europe, at the meeting "Health in Action reforming the Greek National Health System to Improve Citizens’ Health", on 5 March 2014, Athens, Greece.
Description about recent outbreak of Ebola virus in West African countries with history, pathogenesis, clinical signs and prevention measures of Filoviruses are presented in comprehensive manner.
Vector-borne diseases-Malaria, Filariasis, Dengue, JE, YF, Chikungunya, KFD, Leishmaniasis and the national program against vector-borne diseases NVBDCP.
Description about recent outbreak of Ebola virus in West African countries with history, pathogenesis, clinical signs and prevention measures of Filoviruses are presented in comprehensive manner.
Vector-borne diseases-Malaria, Filariasis, Dengue, JE, YF, Chikungunya, KFD, Leishmaniasis and the national program against vector-borne diseases NVBDCP.
HIV (Human Immunodeficiency Virus) infects cells of the immune system and destroys or impairs their function.
Infection progressive deterioration of the immune system breaking down the body's ability to fight out infections & diseases by opportunistic bacteria, viruses and fungi.
AIDS (Acquired Immune Deficiency Syndrome) refers to the most advanced stages of HIV infection and a collection of signs and symptoms caused by more than 20 opportunistic infections or related cancers.
At the end of the session, the students shall be able to
Describe the HIV AIDS introduction, epidemiology of HIV AIDS, diagnosis of HIV AIDS, treatment of HIV AIDS and prevention control of HIV AIDS.
Presentation on HIV/AIDS, public health concern- include cause, symptoms, prevention and appropriate interventions. Also it include the Epidemiological Triangle link between agent, host and environment, Status of the disease in Nepal and in world.
HOT NEW PRODUCT! BIG SALES FAST SHIPPING NOW FROM CHINA!! EU KU DB BK substit...GL Anaacs
Contact us if you are interested:
Email / Skype : kefaya1771@gmail.com
Threema: PXHY5PDH
New BATCH Ku !!! MUCH IN DEMAND FAST SALE EVERY BATCH HAPPY GOOD EFFECT BIG BATCH !
Contact me on Threema or skype to start big business!!
Hot-sale products:
NEW HOT EUTYLONE WHITE CRYSTAL!!
5cl-adba precursor (semi finished )
5cl-adba raw materials
ADBB precursor (semi finished )
ADBB raw materials
APVP powder
5fadb/4f-adb
Jwh018 / Jwh210
Eutylone crystal
Protonitazene (hydrochloride) CAS: 119276-01-6
Flubrotizolam CAS: 57801-95-3
Metonitazene CAS: 14680-51-4
Payment terms: Western Union,MoneyGram,Bitcoin or USDT.
Deliver Time: Usually 7-15days
Shipping method: FedEx, TNT, DHL,UPS etc.Our deliveries are 100% safe, fast, reliable and discreet.
Samples will be sent for your evaluation!If you are interested in, please contact me, let's talk details.
We specializes in exporting high quality Research chemical, medical intermediate, Pharmaceutical chemicals and so on. Products are exported to USA, Canada, France, Korea, Japan,Russia, Southeast Asia and other countries.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
Follow us on: Pinterest
Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
2. CONTENTS
Introduction
Background
Epidemiological
Epidemiological triad
Epidemiological determinant
Statement of problem
Rational of the seminar
Objective
Methodology
Findings
3. Background
HIV stands for Human Immune deficiency Virus.
If it is not treated it can leads to acquired immunodeficiency
syndrome (AIDS).
HIV Specially attacks the body immune system the CD4 cells
(T cells).
Untreated HIV reduces the number of CD$ cells (T cells) in
the body , making the person more likely to get infections or
infection related cancers.
4. Stages of HIV infection
Stage 1 : No AIDS – defining condition
CD4 count of >_ 500 cells /uL of CD4 percentage of total lymphocytes of >_29
Stage 2: No AIDS – definition condition
CD4 count <200 cells/uL or CD4 percentage of total lymphocytes<14
HIV infection ,stage unknow:
No reported information on AIDS-defining condition and no information
available on CD4 count or percentage.
AIDS (Acquired immune deficiency syndrome) is the final stage of HIV
infection , which causes damaged to the immune system.
5. HISTORY
AIDS wad first identified in USA in 1981 when numbers of
gay men started to develop life threatening opportunistic and
cancer.
In 1981 AIDS was first identified among gay men in USA.
In 1983 discovery of a new retrovirus called
lymphadenopathy-Associated virus (or LAV)
6. HISTORY
In 1983 world health organization first meeting to assess
global AIDS situation.
In 1984 virus was isolated by Gallo and coworkers from
national institution of health in united state human T-call
lymph tropic virus III (HTLV-III).
1985 , the U.S. Food and Drug Administration (FDA
)licensed the first commercial blood test, ELISA, to detect
antibodies to the virus.
7. HISTORY
in 1985 first international AIDS conference in Atlanta Georgia.
In May 1986, the International Committee on the Taxonomy of
Viruses gave a new name called (human immunodeficiency virus)
instead of HTLV-III/LAV.
In 1988, the WHO declared 1st December as the first World AIDS
Day.
Since its identification , HIV/AIDS is devastating disease of
mankind.
11. Agent
HIV 1 HIV 2
HIV-1 more common worldwide HIV-2 found in west Africa , Mozambique , and
Angola,
HIV-1 is more pathogenic hIV-2 is less pathogenic
MTCT is relatively common with HIV-1 Duration of HIV-2 infection is shorter
12.
13. HOST FACTORS
Age: 20-49
Sex: HIV infection people of any sex
Europe And Australia : 51% homosexual or bisexual man
Africa: Sex ratio is equal
Higher Risk group :
• prostitutes (heterosexual)
• Male homosexual and bisexual
• Intravenous drug abuser
• Transfusion recipient of blood and blood products
• Hemophiliacs and clients of STD
15. Factor of HIV AIDS
Behaviors and condition that put individuals at greater risk of
contracting HIV include:
Having unprotected anal or veginal sex:
Having another sexually transmitted infection such as
syphilis, herpes , chlamydia gonorrhea and bacterial vaginosis
16. Risk Factor of HIV AIDS
Sharing contaminated needles, syringe and other injection
equipment and drug solution when injection drugs
Receiving unsafe injection , blood transfusion tissue
transplantation , medical procedure that involve unsterile
cutting or piercing and
Experiencing accidental needle stick injuries including among
Health workers.
18. Determinant for HIV AIDS
Economic status : poverty
Poor education : low literacy regarding HIV and AIDS
Occupation : laborers , migrants , transport workers police
militaries, surgeons
Political system :
conflicts in country resulting in:
19. Determinants for HIV AIDS
Gender inequalities : more in male
Inadequate health care delivery system
Migration and mobility
Alcoholism and drug abuse
Legal framework
Change values : early sex
High population growth and density
20.
21. Statement of Problem
GLOBAL SCENARIO
Prevalence of HIV increased from 29.8 million in 2001 to 36.9
million in 2014
Globally 36.7 million people are living with HIV in 2016
World wide 1.8 million people become newly infected with HIV.
54% of adult and 43% of children living with HIV are
currently receiving lifelong antiretroviral therapy (ART)
22. Global scenario
world wide 1 million people died from AIDS related illness in
2016.
Global ART coverage for pregnant and breastfeeding women
living with HIV is high at 76%.
The WHO African region is the most affected region with
25.6 million people living with HIV in 2016. The African
region also accounts for almost two third of the global total of
new HIV infection.
24. National Scenario
In India , first case of HIV /AIDS was diagnosed in 1989 , by
Dr. Suniti soloman and her student Dr. Sellappan Nirmala in
Chennai.
Prevalence of AIDS in India in 2015 was 0.20% which is
down from 0.41 in 2002.
Number estimated 2.11 million people live with HIV/AIDS in
India in 2015.
27. Rational of the seminar
Recognized as an emerging disease only in the early 1980 ,
AIDS has rapidly established itself throughout the world , and
is likely to ensure and persist well in 21st century.
AIDS has evolved from a mysterious illness to a global
pandemic which has infected tens of million people.
Among the special features of HIV infection are that once
infected , it is probably that a person will be infected for life.
28. Objectives
General objective
To study epidemiology and overview of current policies , strategies
and programs for prevention and control of HIV AIDS
Specific Objectives
To explore epidemiological distribution and determinants of HIV
AIDS.
To review the milestone of HIV AIDS control in India.
29. Objectives
To evaluate the current situation of HIV AIDS control
program.
To discuss on policy and strategies on HIV AIDS.
To explore prevention and control methods of HIV AIDS.
36. Findings
Window period
6 weeks to 3 months
Incubation period
uncertain ( from few months to 10 Yrs from HIV infection
to development of AIDS )
37. Clinical Features
The clinical presentation of HIV and AIDS has been divided
in to four phase of infection.
1. Primary infection
2. Asymptomatic carrier stage
3. AIDS related complex
4. Progression to AIDS
45. Prevention , Control and Treatment
PRIMARY: Primary prevention refers to activity focused on
preventing uninfected people becoming infected.
Health education
Peer group education
School curriculum
Most at risk population
Behavioral modification
Specific protection
47. Tertiary
Tertiary HIV prevention aims to minimize the effects of ill
health experience by someone who is symptomatic with HIV
disease (i.e. the prophylactic use of drug and complementary
Rehabilitation
Economic
Social
vocational