2. Maball 500mg is a anticancer medicine which
prevents the growth and spread of cancer cells
in the body.
Maball 500mg injection also indicated for the
treatment of Non- Hodgkins lymphoma or chronic
lymphocytic and with combination with another
anticancer drugs like methotrexate is used for
rheumatoid arthritis symptoms in adult
treatment.
Maball 500mg with steroid regimen combination
is given for the treatment of some rare disorders
which cause blood vessels and other tissues
inflammation in the body.
3. Maball 500mg injection and hyaluronidase human
injection are given alone or combination with
another drugs to treat certain types of non-
Hodgkin's lymphoma and chronic lymphocytic
leukemia (cancer start in WBC).
Maball 500mg injection is also used with
methotrexate (Otrexup, Rasuvo, Xatmep, others)
for the treatment rheumatoid arthritis symptoms
in adults that have been already treated with a
some type of regimen known as tumor necrosis
factor (TNF) inhibitor.
Maball 500mg is a type in a classification of
drugs called monoclonal antibodies.
4.
5. new type of "targeted" cancer treatment and an integral
part of the body's immune system. Naturally the body build
antibodies in along with to an antigen which has entered
the body and attach to the antigen for destruction by the
immune system. An essential cells only aimed by
monoclonal antibiotics, they may leads to less toxicity to
healthy cell and it is usually treatment recommended only
for cancers in which antigens (and the respective
antibodies) have been already identified. Maball works by
linking to the CD20 antigen on normal and malignant B-
cells. Hence the body's essential immune security are
initiated to attack and kill the marked B-cells. Stem cells
i.eyoung cells in the bone marrow which will grow into the
various cell types and do not have the CD20 antigen. After
treatment,CD20 antigen allows healthy B-cells to multiply
7. ABSORPTION
Not available
DISTRIBUTION
volume of distribution is 3.1 L
METABOLISM
Maball 500mg metabolized by human antimurine
antibody production.
EXCRETION
not available The half life of NHL is 22 days and
for RA is 18.0 days, GPA and microscopic
polyangitis is 23 days
8. Allgeric condition against Maball 500mg
injection or any other medication informs your
doctor. Concerning your past history of drug used
which include in prescription, non-prescription,
vitamins &supplements, nutritional products just
inform the doctor.
While using Maball 500mg do not take any
vaccination or immunization without taking
advice from doctors.
Avoid use of Maball 500mg injection may affect
the ability to have children in women. Inform
your doctor if you planning to pregnant. It is
unknown whether Maball 500mg passes into
breast milk , avoid breast-feed while on Maball
500mg injection treatment.
9. Allgeric condition against Maball 500mg or any
other medication informs your doctor.
Concerning your past history of drug used which
include in prescription, non-prescription,
vitamins &supplements, nutritional products just
inform the doctor.
While using Maball 500mg injection do not take
any vaccination or immunization without taking
advice from doctors. Avoid use of Maball 500mg
if you are pregnant. It will harm the baby
unborn, while using Maball 500mg use correct
birth control to prevent pregnancy and for at
least 2 weeks after your treatment ends.
10. COMMON EFFECTS
fever and chills (flu lik symptoms)LESS
COMMON SIDE EFFECTS
Weakness; nausea; headache; cough;
dyspnae; pharyngitis
11. Maball 500mg drug interaction has limited
data is available at present. Combination
with fludarabine or cyclophosphamide has no
effects in pharmacokinetics in CLL patients.
Combination with methotrexate had no
effects in pharmacokinetics.
12. Hypersensitivity or murine proteins. Active
severe infectons in rheumatoid arthritis
Uncontrolled cardiac disease.
13. CategoryC : animal studies reproduction
shown an adverse effect on the fetus. The
drug has no sufficient and well controlled
studies in humans, using in pregnant women
benefits by warrant use of the drug.
14. Maball 500mg excreted into human milk is
unknown. Due to the drug belongs to large
protein molecule, no information is
available. Women should not breast feed
during Maball 500mg injection treatment and
12 months following last dose.
15. Store at 2°C – 3°C
Use the drug before expiry date
Protected from direct sunlight
Do not freeze or shake.
Keep away from the childerns
Discard the unused drug by asking the advice
from doctor or pharmacist.
16. If a dose missed to take at the time then
have it suddenly before next dose timing, if
time reach for next dose, then skip missed
dose and continue and continue the regular
schedule. Do not have 2 dose at a same time.