This document summarizes Dr. Larry Smarr's presentation on quantifying physiological data from his own body over the past decade. Some key points: - Smarr has gathered longitudinal time series data on over 200 biomarkers and microbiome samples to study phenotype changes from his autoimmune disease. - Sensors have tracked daily metrics like weight, activity levels, and symptoms, revealing oscillations and episodes of inflammation. - Imaging and biomarker analysis identified the specific location and nature of his Crohn's disease. - Analysis of his microbiome samples over time uncovered a shift in microbial ecology that correlated with changes in drugs and symptoms. - Expanding this type of personalized, quantitative approach could transform medicine by deeply characterizing individuals