The document discusses how organizations can gain a competitive advantage through Lean Six Sigma by satisfying customers and eliminating waste. It reports that Lean Six Sigma has led to improvements like 100% improved labor standards, 90% improved product flow, and 50% reductions in scrap and product development time. The document outlines where to start improving at the enterprise level and lists key success factors like management involvement, executive sponsors, process owners, and using a Lean Six Sigma approach with teamwork and project management. It also explains when to use Lean versus Six Sigma and provides an overview of their approaches and major tools.