Laser stop smoking
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Laser stop smoking therapies include nicotine replacement therapy, nicotine-free medications, and acupuncture. Nicotine replacement therapy supplies nicotine externally through patches, gum, inhalers or other forms to reduce cravings and withdrawal symptoms while avoiding other harmful chemicals in cigarettes. Nicotine-free medications like Varenicline and Bupropion are FDA-approved prescription drugs that can help relieve withdrawal symptoms for those who find it difficult to quit cold turkey. Acupuncture aims to release endorphins and promote feelings of well-being to distract from withdrawal symptoms.
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GASTROINTESTINAL INFECTIONS AND GASTRITIS
Osvaldo Bernardo Muchanga
Gastrointestinal Infections
GASTROINTESTINAL INFECTIONS result from the ingestion of pathogens that cause infections at the level of this tract, generally being transmitted by food, water and hands contaminated by microorganisms such as E. coli, Salmonella, Shigella, Vibrio cholerae, Campylobacter, Staphylococcus, Rotavirus among others that are generally contained in feces, thus configuring a FECAL-ORAL type of transmission.
Among the factors that lead to the occurrence of gastrointestinal infections are the hygienic and sanitary deficiencies that characterize our markets and other places where raw or cooked food is sold, poor environmental sanitation in communities, deficiencies in water treatment (or in the process of its plumbing), risky hygienic-sanitary habits (not washing hands after major and/or minor needs), among others.
These are generally consequences (signs and symptoms) resulting from gastrointestinal infections: diarrhea, vomiting, fever and malaise, among others.
The treatment consists of replacing lost liquids and electrolytes (drinking drinking water and other recommended liquids, including consumption of juicy fruits such as papayas, apples, pears, among others that contain water in their composition).
To prevent this, it is necessary to promote health education, improve the hygienic-sanitary conditions of markets and communities in general as a way of promoting, preserving and prolonging PUBLIC HEALTH.
Gastritis and Gastric Health
Gastric Health is one of the most relevant concerns in human health, with gastrointestinal infections being among the main illnesses that affect humans.
Among gastric problems, we have GASTRITIS AND GASTRIC ULCERS as the main public health problems. Gastritis and gastric ulcers normally result from inflammation and corrosion of the walls of the stomach (gastric mucosa) and are generally associated (caused) by the bacterium Helicobacter pylor, which, according to the literature, this bacterium settles on these walls (of the stomach) and starts to release urease that ends up altering the normal pH of the stomach (acid), which leads to inflammation and corrosion of the mucous membranes and consequent gastritis or ulcers, respectively.
In addition to bacterial infections, gastritis and gastric ulcers are associated with several factors, with emphasis on prolonged fasting, chemical substances including drugs, alcohol, foods with strong seasonings including chilli, which ends up causing inflammation of the stomach walls and/or corrosion. of the same, resulting in the appearance of wounds and consequent gastritis or ulcers, respectively.
Among patients with gastritis and/or ulcers, one of the dilemmas is associated with the foods to consume in order to minimize the sensation of pain and discomfort. Breast cancer: Post menopausal endocrine therapy
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
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The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
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Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
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Discuss and demonstrate the approaches with array and NGS genotyping methods for star allele calling to prep for downstream analysis.
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- 2. 1) Nicotine replacement therapy It is an effective and popular aid for smoking cessation. This particular therapy is aimed at supplying nicotine externally to the body through numerous forms like nicotine patches, gum, inhaler, lozenges, nasal spray and sublingual tablets.
- 3. When the body gets nicotine in such forms it will no longer craves cigarettes, which aside from including nicotine, is also made up of 4,000 additional damaging chemical substances.Therefore, nicotine replacement therapy helps to protect you from the dangerous chemicals and simultaneously reduces your withdrawal discomforts.
- 4. Furthermore, this laser stop smoking therapy will give you an opportunity to escape the smoking habits in your everyday life and offers you a more painless and convenient experience for you to stop smoking. In order to obtain the ideal results from this particular treatment you have to use it along with getting support from family and friends or even a professional counselor.
- 5. 2) Free nicotine medications to quit smoking At present, this is the most highly developed aids for smoking cessation. The nicotine-free medications which can be found in the marketplace consist of VareniclineTartrate (Chantix) and Bupropion Hydrochloride (Zyban). These two medications are authorized by the US Food and drug administration as a prescription drug for smoking cessation.
- 6. These medications are well suited for people who are determined to quit, yet find it difficult to do so through the cold turkey approach because of symptoms of nicotine withdrawal. Those two can help to relieve symptoms of nicotine withdrawal.
- 7. 3) Acupuncture This laser stop smoking therapy aims at discharging endorphins, also called the feel good hormones and this will encourage a sense of well-being and contentment as well as keep the mind from withdrawal symptoms.